Literature DB >> 2578671

Internal antigen and immune network.

H Kohler, S Muller, C Bona.   

Abstract

The network hypothesis postulates the existence of internal idiotopic structures which mimic nominal antigens. Experimental evidence for idiotope internal antigen is presented and its implication for the Network hypothesis is discussed. The exploitation of the internal idiotope antigens (or preparation of vaccines) is a realistic possibility.

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Year:  1985        PMID: 2578671     DOI: 10.3181/00379727-178-41996a

Source DB:  PubMed          Journal:  Proc Soc Exp Biol Med        ISSN: 0037-9727


  8 in total

1.  Biological mimicry of antigenic stimulation: analysis of the in vivo antibody responses induced by monoclonal anti-idiotypic antibodies.

Authors:  J Y Huang; R E Ward; H Kohler
Journal:  Immunology       Date:  1988-01       Impact factor: 7.397

2.  Discrimination of the determinant specificity of two competitive Semliki Forest virus neutralizing monoclonal antibodies by anti-idiotypic antibodies.

Authors:  T A Oosterlaken; C A Kraaijeveld; A Snijders; M Harmsen; B J Benaissa-Trouw; H Snippe
Journal:  Arch Virol       Date:  1988       Impact factor: 2.574

Review 3.  Cross-reacting idiotypes on cryoprecipitating rheumatoid factor.

Authors:  P P Chen; S Fong; F Goni; G J Silverman; R I Fox; M F Liu; B Frangione; D A Carson
Journal:  Springer Semin Immunopathol       Date:  1988

4.  Development and characterization of an anti-idiotype antibody to the capsular polysaccharide of Neisseria meningitidis serogroup C.

Authors:  M A Westerink; A A Campagnari; M A Wirth; M A Apicella
Journal:  Infect Immun       Date:  1988-05       Impact factor: 3.441

5.  Isolation of alpaca anti-idiotypic heavy-chain single-domain antibody for the aflatoxin immunoassay.

Authors:  Yanru Wang; Peiwu Li; Zuzana Majkova; Candace R S Bever; Hee Joo Kim; Qi Zhang; Julie E Dechant; Shirley J Gee; Bruce D Hammock
Journal:  Anal Chem       Date:  2013-08-21       Impact factor: 6.986

6.  Antiidiotypic antibody vaccine in murine Schistosomiasis mansoni comprising the internal image of antigen.

Authors:  T F Kresina; G R Olds
Journal:  J Clin Invest       Date:  1989-03       Impact factor: 14.808

7.  Idiotypic self binding of a dominant germline idiotype (T15). Autobody activity is affected by antibody valency.

Authors:  C Y Kang; H L Cheng; S Rudikoff; H Kohler
Journal:  J Exp Med       Date:  1987-05-01       Impact factor: 14.307

8.  Immunoglobulin with complementary paratope and idiotope.

Authors:  C Y Kang; H Kohler
Journal:  J Exp Med       Date:  1986-04-01       Impact factor: 14.307

  8 in total

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