Literature DB >> 25781291

Issues with Consent in Stroke Patients.

J P Mamo1.   

Abstract

BACKGROUND: Consent in stroke management may be required for either treatment, intervention or for research reasons. Consent capacity is an integral element of informed consent to treatment which requires that a patient's consent be voluntary, informed, and competent. Without proper informed consent, medical treatment provided to a patient is a legal and ethical minefield, even if the treatment is benign and intended to benefit the patient.
RESULTS: Recent advances have enabled dramatic recovery in some stroke victims, transforming the previously generally negative outcomes of stroke care, whereas others face varying levels of disability. Explaining and sharing such details with patients and their families is essential. If this is not possible then there are other options such as emergency consent which may be justified in specific scenarios. Stroke may affect various areas of the brain and this may also include the prefrontal cortex which is involved in decision-making. There have been observations that individuals with damage to the ventro-medial prefrontal cortex may be prone to impulsive decision-making in real life and these patients are impaired on laboratory decision- making tasks that require balancing rewards, punishments and risk. This may therefore have an impact on consent decisions made by the patient.
CONCLUSIONS: Ethical clinical research requires balancing several ethical requirements, including the requirement for scientific validity and the requirement to respect individuals by treating them as autonomous agents through the process of informed consent. Opportunities to improve on public awareness about stroke are essential to change the perception of this potentially devastating disorder.

Entities:  

Year:  2014        PMID: 25781291      PMCID: PMC4655695          DOI: 10.7727/wimj.2013.134

Source DB:  PubMed          Journal:  West Indian Med J        ISSN: 0043-3144            Impact factor:   0.171


  16 in total

1.  What has gone wrong in stroke research?

Authors:  S J Ellis; C Matthews
Journal:  Postgrad Med J       Date:  1999-08       Impact factor: 2.401

2.  Informed consent, exploitation and whether it is possible to conduct human subjects research without either one.

Authors:  D Wendler
Journal:  Bioethics       Date:  2000-10       Impact factor: 1.898

3.  Selecting a surrogate to consent to medical research.

Authors:  R Amdur; N Bachir; E Stanton
Journal:  IRB       Date:  2000 Jul-Aug

4.  Different underlying impairments in decision-making following ventromedial and dorsolateral frontal lobe damage in humans.

Authors:  Lesley K Fellows; Martha J Farah
Journal:  Cereb Cortex       Date:  2004-06-24       Impact factor: 5.357

Review 5.  Epidemiology of stroke.

Authors:  C P Warlow
Journal:  Lancet       Date:  1998-10       Impact factor: 79.321

6.  In case of emergency: no need for consent.

Authors:  B A Brody; J Katz; A Dula
Journal:  Hastings Cent Rep       Date:  1997 Jan-Feb       Impact factor: 2.683

7.  Projection in surrogate decisions about life-sustaining medical treatments.

Authors:  A Fagerlin; P H Ditto; J H Danks; R M Houts; W D Smucker
Journal:  Health Psychol       Date:  2001-05       Impact factor: 4.267

8.  Stroke patients' preferences and values about emergency research.

Authors:  C E Blixen; G J Agich
Journal:  J Med Ethics       Date:  2005-10       Impact factor: 2.903

9.  Perceived needs of wives of stroke patients.

Authors:  S G Rosenthal; M J Pituch; L O Greninger; E S Metress
Journal:  Rehabil Nurs       Date:  1993 May-Jun       Impact factor: 1.625

10.  Impact of restricting enrollment in stroke genetics research to adults able to provide informed consent.

Authors:  Donna T Chen; L Douglas Case; Thomas G Brott; Robert D Brown; Scott L Silliman; James F Meschia; Bradford B Worrall
Journal:  Stroke       Date:  2008-02-07       Impact factor: 7.914

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