Literature DB >> 25767429

Phenolization and coralline hydroxyapatite grafting following meticulous curettage for the treatment of enchondroma of the hand. A case series of 82 patients with 5-year follow-up.

Dimitrios Georgiannos1, Vasilios Lampridis2, Ilias Bisbinas2.   

Abstract

BACKGROUND: Enchondromas are benign cartilaginous tumours. The most common location is in the long bones of the hand. Treatment methods fall into a broad spectrum ranging from conservative, medical therapies, to a variety of surgical procedures, which may or may not employ the use of local adjuvant treatment or bone grafting. The purpose of this study was to report our experience and evaluate the long-term results of patients with enchondroma of the hand, treated in our department with meticulous curettage, phenolization and coralline hydroxyapatite grafting.
METHODS: We present 82 patients with hand enchondromas treated surgically in our department during the last 10 years. The patients were treated operatively with meticulous curettage of the bone lesion, with use of phenol 5 % as local adjuvant and coralline hydroxyapatite bone graft to fill in the remaining cavity.
RESULTS: At a minimum of 5-year follow-up, radiographs and clinical examination showed adequate bone formation at the site of enchondroma excavation and no evidence of recurrence, fracture, infection or other complication related to the procedure.
CONCLUSION: We concluded that the combination of meticulous curettage of the lesion, with the use of phenol as local adjuvant and coralline hydroxyapatite graft is a safe technique that prevents recurrence and allows adequate and uncomplicated local new bone formation.

Entities:  

Keywords:  Adjuvant therapy; Coralline hydroxyapatite; Enchondroma; Phenol; Recurrence; Surgical treatment

Year:  2015        PMID: 25767429      PMCID: PMC4349847          DOI: 10.1007/s11552-014-9674-2

Source DB:  PubMed          Journal:  Hand (N Y)        ISSN: 1558-9447


  32 in total

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Journal:  Am J Orthop (Belle Mead NJ)       Date:  2001-07

2.  The treatment of enchondromas in the hand by endoscopic curettage without bone grafting.

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3.  The use of cryosurgery in the treatment of low and medium grade chondrosarcoma. A preliminary report.

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4.  Phenol as an adjuvant for local control in the treatment of giant cell tumour of the bone.

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Journal:  Eur J Surg Oncol       Date:  1999-12       Impact factor: 4.424

5.  Coralline hydroxyapatite bone graft substitute: A review of experimental studies and biomedical applications.

Authors:  E Damien; P A Revell
Journal:  J Appl Biomater Biomech       Date:  2004 May-Aug

6.  Curettage and calcium phosphate bone cement injection for the treatment of enchondroma of the finger.

Authors:  Jae Kwang Kim; Nam Ki Kim
Journal:  Hand Surg       Date:  2012

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Journal:  Clin Orthop Relat Res       Date:  1985-12       Impact factor: 4.176

8.  Tumours of the hand presenting as pathological fractures.

Authors:  Ravikiran Shenoy; Anand Pillai; Robin Reid
Journal:  Acta Orthop Belg       Date:  2007-04       Impact factor: 0.500

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Journal:  J Bone Joint Surg Br       Date:  1979-11

10.  Curettage of benign bone tumors without grafts gives sufficient bone strength.

Authors:  Takashi Yanagawa; Hideomi Watanabe; Tetsuya Shinozaki; Kenji Takagishi
Journal:  Acta Orthop       Date:  2009-02       Impact factor: 3.717

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  4 in total

1.  Surgical treatment for symptomatic non-ossifying fibromas of the lower extremity with calcium sulfate grafts in skeletally immature patients.

Authors:  Antonio Andreacchio; Flavia Alberghina; Gianluca Testa; Federico Canavese
Journal:  Eur J Orthop Surg Traumatol       Date:  2017-08-17

2.  A New Self-Healing Hydrogel Containing hucMSC-Derived Exosomes Promotes Bone Regeneration.

Authors:  Li Wang; Jian Wang; Xiangbin Zhou; Jie Sun; Biao Zhu; Cuimi Duan; Peng Chen; Ximin Guo; Tong Zhang; Hongyan Guo
Journal:  Front Bioeng Biotechnol       Date:  2020-09-10

3.  The healing of alveolar bone defects with novel bio-implants composed of Ad-BMP9-transfected rDFCs and CHA scaffolds.

Authors:  Li Nie; Xia Yang; Liang Duan; Enyi Huang; Zhou Pengfei; Wenping Luo; Yan Zhang; Xingqi Zeng; Ye Qiu; Ting Cai; Conghua Li
Journal:  Sci Rep       Date:  2017-07-25       Impact factor: 4.379

4.  Enchondromas of the Hand: A 20-year Experience.

Authors:  Claudio Sollaci; Gabriel Costa Serrão de Araújo
Journal:  Rev Bras Ortop (Sao Paulo)       Date:  2019-10-09
  4 in total

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