Literature DB >> 25763882

Proteo-lipobeads for the oriented encapsulation of membrane proteins.

Pinar Frank1, Bernhard Siebenhofer1, Theresa Hanzer1, Andreas F Geiss1, Florian Schadauer1, Ciril Reiner-Rozman1, Bill Durham2, Leslie M Loew3, Bernd Ludwig4, Oliver-M H Richter4, Christoph Nowak5, Renate L C Naumann2.   

Abstract

As a surrogate of live cells, proteo-lipobeads are presented, encapsulating functional membrane proteins in a strict orientation into a lipid bilayer. Assays can be performed just as on live cells, for example using fluorescence measurements. As a proof of concept, we have demonstrated proton transport through cytochrome c oxidase.

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Year:  2015        PMID： 25763882      PMCID： PMC4387127          DOI： 10.1039/c4sm02646b

Source DB:  PubMed          Journal:  Soft Matter        ISSN： 1744-683X            Impact factor:   3.679


  11 in total

1.  Cell-based assays and instrumentation for screening ion-channel targets.

Authors: 
Journal:  Drug Discov Today       Date:  1999-09       Impact factor: 7.851

2.  Paramagnetic proteoliposomes containing a pure, native, and oriented seven-transmembrane segment protein, CCR5.

Authors:  T Mirzabekov; H Kontos; M Farzan; W Marasco; J Sodroski
Journal:  Nat Biotechnol       Date:  2000-06       Impact factor: 54.908

3.  Net proton uptake is preceded by multiple proton transfer steps upon electron injection into cytochrome c oxidase.

Authors:  Kristina Kirchberg; Hartmut Michel; Ulrike Alexiev
Journal:  J Biol Chem       Date:  2012-01-11       Impact factor: 5.157

4.  A multitechnique study of liposome adsorption on Au and lipid bilayer formation on SiO2.

Authors:  E Reimhult; M Zäch; F Höök; B Kasemo
Journal:  Langmuir       Date:  2006-03-28       Impact factor: 3.882

5.  A membrane-reconstituted multisubunit functional proton pump on mesoporous silica particles.

Authors:  Gustav Nordlund; Jovice Boon Sing Ng; Lennart Bergström; Peter Brzezinski
Journal:  ACS Nano       Date:  2009-09-22       Impact factor: 15.881

6.  Drug-target network.

Authors:  Muhammed A Yildirim; Kwang-Il Goh; Michael E Cusick; Albert-László Barabási; Marc Vidal
Journal:  Nat Biotechnol       Date:  2007-10       Impact factor: 54.908

7.  In vitro expressed GPCR inserted in polymersome membranes for ligand-binding studies.

Authors:  Sylvia May; Mirjam Andreasson-Ochsner; Zhikang Fu; Ying Xiu Low; Darren Tan; Hans-Peter M de Hoog; Sandra Ritz; Madhavan Nallani; Eva-Kathrin Sinner
Journal:  Angew Chem Int Ed Engl       Date:  2012-11-19       Impact factor: 15.336

8.  The protein-tethered lipid bilayer: a novel mimic of the biological membrane.

Authors:  Frank Giess; Marcel G Friedrich; Joachim Heberle; Renate L Naumann; Wolfgang Knoll
Journal:  Biophys J       Date:  2004-08-31       Impact factor: 4.033

9.  Orientated binding of photosynthetic reaction centers on gold using Ni-NTA self-assembled monolayers.

Authors:  Scott A Trammell; Leyu Wang; Joseph M Zullo; Ranganathan Shashidhar; Nikolai Lebedev
Journal:  Biosens Bioelectron       Date:  2004-07-15       Impact factor: 10.618

10.  Spectra, membrane binding, and potentiometric responses of new charge shift probes.

Authors:  E Fluhler; V G Burnham; L M Loew
Journal:  Biochemistry       Date:  1985-10-08       Impact factor: 3.162
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  3 in total

1.  pH and Potential Transients of the bc1 Complex Co-Reconstituted in Proteo-Lipobeads with the Reaction Center from Rb. sphaeroides.

Authors:  Andreas F Geiss; Raghav Khandelwal; Dieter Baurecht; Christina Bliem; Ciril Reiner-Rozman; Michael Boersch; G Matthias Ullmann; Leslie M Loew; Renate L C Naumann
Journal:  J Phys Chem B       Date:  2017-01-04       Impact factor: 2.991

Review 2.  Biomimetic Membranes for Multi-Redox Center Proteins.

Authors:  Renate L C Naumann; Andreas F Geiss; Christoph Steininger; Wolfgang Knoll
Journal:  Int J Mol Sci       Date:  2016-03-03       Impact factor: 5.923

Review 3.  Compartmentalization and Transport in Synthetic Vesicles.

Authors:  Christine Schmitt; Anna H Lippert; Navid Bonakdar; Vahid Sandoghdar; Lars M Voll
Journal:  Front Bioeng Biotechnol       Date:  2016-02-29
  3 in total

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