PURPOSE: Early central venous catheter (CVC) insertion in Ebola virus disease (EVD) is a novel approach and has not previously been described. This report delineates the safety, feasibility and clinical implications of early CVC insertion as the optimum means of vascular access in patients with EVD, in the setting of a deployed military Ebola virus disease treatment unit in Sierra Leone. METHODS: In the gastrointestinal phase of EVD, a 7-French 20-cm triple-lumen CVC was inserted using aseptic technique. Data were collected prospectively on all cases to include baseline and subsequent blood test variables, insertion site and technique, and complications associated with CVC placement. RESULTS: Twenty-three patients underwent CVC insertion as follows: subclavian, 21 (88 %); internal jugular, 2 (8 %); axillary, 1 (4 %). The mean duration of CVC placement was 5 days. There were no significant procedure-related adverse events. Despite coagulopathy being present in 75 % of cases, CVC insertion was safe, and there was only 1 case of significant catheter site bleeding. A total of 152 needle venepunctures were avoided owing to the presence of a CVC, a mean of 7 (±3.8) per case over the average stay. CONCLUSION: The early use of CVCs in Ebola virus disease is safe, effective and facilitates patient care. It should be considered a feasible additional route of venous access, where physician expertise and resources allow.
PURPOSE: Early central venous catheter (CVC) insertion in Ebola virus disease (EVD) is a novel approach and has not previously been described. This report delineates the safety, feasibility and clinical implications of early CVC insertion as the optimum means of vascular access in patients with EVD, in the setting of a deployed military Ebola virus disease treatment unit in Sierra Leone. METHODS: In the gastrointestinal phase of EVD, a 7-French 20-cm triple-lumen CVC was inserted using aseptic technique. Data were collected prospectively on all cases to include baseline and subsequent blood test variables, insertion site and technique, and complications associated with CVC placement. RESULTS: Twenty-three patients underwent CVC insertion as follows: subclavian, 21 (88 %); internal jugular, 2 (8 %); axillary, 1 (4 %). The mean duration of CVC placement was 5 days. There were no significant procedure-related adverse events. Despite coagulopathy being present in 75 % of cases, CVC insertion was safe, and there was only 1 case of significant catheter site bleeding. A total of 152 needle venepunctures were avoided owing to the presence of a CVC, a mean of 7 (±3.8) per case over the average stay. CONCLUSION: The early use of CVCs in Ebola virus disease is safe, effective and facilitates patient care. It should be considered a feasible additional route of venous access, where physician expertise and resources allow.
Authors: Benno Kreuels; Dominic Wichmann; Petra Emmerich; Jonas Schmidt-Chanasit; Geraldine de Heer; Stefan Kluge; Abdourahmane Sow; Thomas Renné; Stephan Günther; Ansgar W Lohse; Marylyn M Addo; Stefan Schmiedel Journal: N Engl J Med Date: 2014-10-22 Impact factor: 91.245
Authors: John S Schieffelin; Jeffrey G Shaffer; Augustine Goba; Michael Gbakie; Stephen K Gire; Andres Colubri; Rachel S G Sealfon; Lansana Kanneh; Alex Moigboi; Mambu Momoh; Mohammed Fullah; Lina M Moses; Bethany L Brown; Kristian G Andersen; Sarah Winnicki; Stephen F Schaffner; Daniel J Park; Nathan L Yozwiak; Pan-Pan Jiang; David Kargbo; Simbirie Jalloh; Mbalu Fonnie; Vandi Sinnah; Issa French; Alice Kovoma; Fatima K Kamara; Veronica Tucker; Edwin Konuwa; Josephine Sellu; Ibrahim Mustapha; Momoh Foday; Mohamed Yillah; Franklyn Kanneh; Sidiki Saffa; James L B Massally; Matt L Boisen; Luis M Branco; Mohamed A Vandi; Donald S Grant; Christian Happi; Sahr M Gevao; Thomas E Fletcher; Robert A Fowler; Daniel G Bausch; Pardis C Sabeti; S Humarr Khan; Robert F Garry Journal: N Engl J Med Date: 2014-10-29 Impact factor: 91.245
Authors: J C Hockenhull; K Dwan; A Boland; G Smith; A Bagust; Y Dündar; C Gamble; C McLeod; T Walley; R Dickson Journal: Health Technol Assess Date: 2008-04 Impact factor: 4.014
Authors: Bruce Aylward; Philippe Barboza; Luke Bawo; Eric Bertherat; Pepe Bilivogui; Isobel Blake; Rick Brennan; Sylvie Briand; Jethro Magwati Chakauya; Kennedy Chitala; Roland M Conteh; Anne Cori; Alice Croisier; Jean-Marie Dangou; Boubacar Diallo; Christl A Donnelly; Christopher Dye; Tim Eckmanns; Neil M Ferguson; Pierre Formenty; Caroline Fuhrer; Keiji Fukuda; Tini Garske; Alex Gasasira; Stephen Gbanyan; Peter Graaff; Emmanuel Heleze; Amara Jambai; Thibaut Jombart; Francis Kasolo; Albert Mbule Kadiobo; Sakoba Keita; Daniel Kertesz; Moussa Koné; Chris Lane; Jered Markoff; Moses Massaquoi; Harriet Mills; John Mike Mulba; Emmanuel Musa; Joel Myhre; Abdusalam Nasidi; Eric Nilles; Pierre Nouvellet; Deo Nshimirimana; Isabelle Nuttall; Tolbert Nyenswah; Olushayo Olu; Scott Pendergast; William Perea; Jonathan Polonsky; Steven Riley; Olivier Ronveaux; Keita Sakoba; Ravi Santhana Gopala Krishnan; Mikiko Senga; Faisal Shuaib; Maria D Van Kerkhove; Rui Vaz; Niluka Wijekoon Kannangarage; Zabulon Yoti Journal: N Engl J Med Date: 2014-09-22 Impact factor: 91.245
Authors: G R Cellarier; J Bordes; L Karkowski; N Gagnon; M Billhot; J M Cournac; C Rousseau; T De Greslan; C Mac Nab; P Dubrous; S Duron; S Moroge; B Quentin Journal: Intensive Care Med Date: 2015-05-08 Impact factor: 17.440
Authors: Julien Bordes; Nicolas Gagnon; Ludovic Karkowsky; Jean Marie Cournac; Claire Rousseau; Magalie Billhot; Thierry de Greslan; Sophie Moroge; Gilles Cellarier Journal: Intensive Care Med Date: 2015-05-14 Impact factor: 17.440
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Authors: Corrado Cancedda; Sheila M Davis; Kerry L Dierberg; Jonathan Lascher; J Daniel Kelly; Mohammed Bailor Barrie; Alimamy Philip Koroma; Peter George; Adikali Alpha Kamara; Ronald Marsh; Manso S Sumbuya; Cameron T Nutt; Kirstin W Scott; Edgar Thomas; Katherine Bollbach; Andrew Sesay; Ahmidu Barrie; Elizabeth Barrera; Kathryn Barron; John Welch; Nahid Bhadelia; Raphael G Frankfurter; Ophelia M Dahl; Sarthak Das; Rebecca E Rollins; Bryan Eustis; Amanda Schwartz; Piero Pertile; Ilias Pavlopoulos; Allan Mayfield; Regan H Marsh; Yusupha Dibba; Danielle Kloepper; Andrew Hall; Karin Huster; Michael Grady; Kimberly Spray; David A Walton; Fodei Daboh; Cora Nally; Sahr James; Gabriel S Warren; Joyce Chang; Michael Drasher; Gina Lamin; Sherry Bangura; Ann C Miller; Annie P Michaelis; Ryan McBain; M Jana Broadhurst; Megan Murray; Eugene T Richardson; Ted Philip; Gary L Gottlieb; Joia S Mukherjee; Paul E Farmer Journal: J Infect Dis Date: 2016-09-28 Impact factor: 5.226
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Authors: S J Dickson; K A Clay; M Adam; C Ardley; M S Bailey; D S Burns; A T Cox; D G Craig; M Espina; I Ewington; G Fitchett; J Grindrod; D E Hinsley; S Horne; E Hutley; A M Johnston; R L C Kao; L E Lamb; S Lewis; D Marion; A J Moore; T C Nicholson-Roberts; A Phillips; J Praught; P S Rees; I Schoonbaert; T Trinick; D R Wilson; A J Simpson; D Wang; M K O'Shea; T E Fletcher Journal: J Infect Date: 2017-12-14 Impact factor: 6.072