Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Nanoscintillator-mediated X-ray inducible photodynamic therapy for in vivo cancer treatment.

Literature DB >> 25756781

Nanoscintillator-mediated X-ray inducible photodynamic therapy for in vivo cancer treatment.

Hongmin Chen^1,2,3,4, Geoffrey D Wang¹, Yen-Jun Chuang⁵, Zipeng Zhen^1,2, Xiaoyuan Chen⁶, Paul Biddinger⁷, Zhonglin Hao⁸, Feng Liu⁵, Baozhong Shen^3,4, Zhengwei Pan⁵, Jin Xie^1,2.

Abstract

Photodynamic therapy is a promising treatment method, but its applications are limited by the shallow penetration of visible light. Here, we report a novel X-ray inducible photodynamic therapy (X-PDT) approach that allows PDT to be regulated by X-rays. Upon X-ray irradiation, the integrated nanosystem, comprised of a core of a nanoscintillator and a mesoporous silica coating loaded with photosensitizers, converts X-ray photons to visible photons to activate the photosensitizers and cause efficient tumor shrinkage.

Entities: CellLine Chemical Disease Gene Species

Keywords: X-PDT; cancer treatment; nanomedicine; nanoscintillator; radioluminescence nanophosphors; singlet oxygen

Mesh：

Substances：

Year: 2015 PMID： 25756781 PMCID： PMC5233724 DOI： 10.1021/nl504044p

Source DB: PubMed Journal: Nano Lett ISSN： 1530-6984 Impact factor: 11.189

35 in total

Review 1. The structural era of endocytosis.

Authors: M Marsh; H T McMahon
Journal: Science Date: 1999-07-09 Impact factor: 47.728

2. Shedding light on the dynamics of endocytosis and viral budding.

Authors: Gang Bao; X Robert Bao
Journal: Proc Natl Acad Sci U S A Date: 2005-07-11 Impact factor: 11.205

3. Photochemistry of singlet oxygen sensor green.

Authors: Sooyeon Kim; Mamoru Fujitsuka; Tetsuro Majima
Journal: J Phys Chem B Date: 2013-10-31 Impact factor: 2.991

4. Biphase stratification approach to three-dimensional dendritic biodegradable mesoporous silica nanospheres.

Authors: Dengke Shen; Jianping Yang; Xiaomin Li; Lei Zhou; Renyuan Zhang; Wei Li; Lei Chen; Rui Wang; Fan Zhang; Dongyuan Zhao
Journal: Nano Lett Date: 2014-01-31 Impact factor: 11.189

Review 5. Exposure, metabolism, and toxicity of rare earths and related compounds.

Authors: S Hirano; K T Suzuki
Journal: Environ Health Perspect Date: 1996-03 Impact factor: 9.031

6. Comparative study of cimetidine and Mylanta II in the 6-week treatment of gastric ulcer.

Authors: R W Sherbaniuk; R H Wensel; R J Bailey; P Kirdeikis; D Fisher; A B Thomson
Journal: J Clin Gastroenterol Date: 1985-06 Impact factor: 3.062

Review 7. Advances in functional X-ray imaging techniques and contrast agents.

Authors: Hongyu Chen; Melissa M Rogalski; Jeffrey N Anker
Journal: Phys Chem Chem Phys Date: 2012-10-21 Impact factor: 3.676

8. Decreased reticuloendothelial system clearance and increased blood half-life and immune cell labeling for nano- and micron-sized superparamagnetic iron-oxide particles upon pre-treatment with Intralipid.

Authors: Li Liu; T Kevin Hitchens; Qing Ye; Yijen Wu; Brent Barbe; Devin E Prior; Wendy F Li; Fang-Cheng Yeh; Lesley M Foley; Daniel J Bain; Chien Ho
Journal: Biochim Biophys Acta Date: 2013-02-08

9. Nanoparticles for Improving Cancer Diagnosis.

Authors: Hongmin Chen; Zipeng Zhen; Trever Todd; Paul K Chu; Jin Xie
Journal: Mater Sci Eng R Rep Date: 2013-03 Impact factor: 36.214

10. Rattle-structured multifunctional nanotheranostics for synergetic chemo-/radiotherapy and simultaneous magnetic/luminescent dual-mode imaging.

Authors: Wenpei Fan; Bo Shen; Wenbo Bu; Feng Chen; Kuaile Zhao; Shengjian Zhang; Liangping Zhou; Weijun Peng; Qingfeng Xiao; Huaiyong Xing; Jianan Liu; Dalong Ni; Qianjun He; Jianlin Shi
Journal: J Am Chem Soc Date: 2013-04-19 Impact factor: 15.419

67 in total

1. Optimized Scintillator YAG:Pr Nanoparticles for X-ray Inducible Photodynamic Therapy.

Authors: Ajay A Sapre; Ekaterina Novitskaya; Ved Vakharia; Alejandro Cota; Wolfgang Wrasidlo; Stephen M Hanrahan; Stephen Derenzo; Milan T Makale; Olivia A Graeve
Journal: Mater Lett Date: 2018-05-20 Impact factor: 3.423

2. X-ray-Based Techniques to Study the Nano-Bio Interface.

Authors: Carlos Sanchez-Cano; Ramon A Alvarez-Puebla; John M Abendroth; Tobias Beck; Robert Blick; Yuan Cao; Frank Caruso; Indranath Chakraborty; Henry N Chapman; Chunying Chen; Bruce E Cohen; Andre L C Conceição; David P Cormode; Daxiang Cui; Kenneth A Dawson; Gerald Falkenberg; Chunhai Fan; Neus Feliu; Mingyuan Gao; Elisabetta Gargioni; Claus-C Glüer; Florian Grüner; Moustapha Hassan; Yong Hu; Yalan Huang; Samuel Huber; Nils Huse; Yanan Kang; Ali Khademhosseini; Thomas F Keller; Christian Körnig; Nicholas A Kotov; Dorota Koziej; Xing-Jie Liang; Beibei Liu; Sijin Liu; Yang Liu; Ziyao Liu; Luis M Liz-Marzán; Xiaowei Ma; Andres Machicote; Wolfgang Maison; Adrian P Mancuso; Saad Megahed; Bert Nickel; Ferdinand Otto; Cristina Palencia; Sakura Pascarelli; Arwen Pearson; Oula Peñate-Medina; Bing Qi; Joachim Rädler; Joseph J Richardson; Axel Rosenhahn; Kai Rothkamm; Michael Rübhausen; Milan K Sanyal; Raymond E Schaak; Heinz-Peter Schlemmer; Marius Schmidt; Oliver Schmutzler; Theo Schotten; Florian Schulz; A K Sood; Kathryn M Spiers; Theresa Staufer; Dominik M Stemer; Andreas Stierle; Xing Sun; Gohar Tsakanova; Paul S Weiss; Horst Weller; Fabian Westermeier; Ming Xu; Huijie Yan; Yuan Zeng; Ying Zhao; Yuliang Zhao; Dingcheng Zhu; Ying Zhu; Wolfgang J Parak
Journal: ACS Nano Date: 2021-03-02 Impact factor: 15.881

Nanoscintillator-mediated X-ray inducible photodynamic therapy for in vivo cancer treatment.

Review 1. The structural era of endocytosis.

2. Shedding light on the dynamics of endocytosis and viral budding.

3. Photochemistry of singlet oxygen sensor green.

4. Biphase stratification approach to three-dimensional dendritic biodegradable mesoporous silica nanospheres.

Review 5. Exposure, metabolism, and toxicity of rare earths and related compounds.

6. Comparative study of cimetidine and Mylanta II in the 6-week treatment of gastric ulcer.

Review 7. Advances in functional X-ray imaging techniques and contrast agents.

8. Decreased reticuloendothelial system clearance and increased blood half-life and immune cell labeling for nano- and micron-sized superparamagnetic iron-oxide particles upon pre-treatment with Intralipid.

9. Nanoparticles for Improving Cancer Diagnosis.

10. Rattle-structured multifunctional nanotheranostics for synergetic chemo-/radiotherapy and simultaneous magnetic/luminescent dual-mode imaging.

1. Optimized Scintillator YAG:Pr Nanoparticles for X-ray Inducible Photodynamic Therapy.

2. X-ray-Based Techniques to Study the Nano-Bio Interface.

3. Nanoscale Metal-Organic Layers for Deeply Penetrating X-ray-Induced Photodynamic Therapy.

4. Activatable Singlet Oxygen Generation from Lipid Hydroperoxide Nanoparticles for Cancer Therapy.

Review 5. Optical and x-ray technology synergies enabling diagnostic and therapeutic applications in medicine.

6. Harnessing the Power of Nanotechnology for Enhanced Radiation Therapy.

7. Activating Photodynamic Therapy in vitro with Cerenkov Radiation Generated from Yttrium-90.

Review 8. Applications of functionalized nanomaterials in photodynamic therapy.

Review 9. Recent advances in photodynamic therapy for cancer and infectious diseases.

10. X-ray induced photodynamic therapy with copper-cysteamine nanoparticles in mice tumors.