Literature DB >> 2575252

Use of somatostatin in the management of pancreatic haemobilia.

M V Tobin1, S A Jenkins, J R Gosney, I T Gilmore.   

Abstract

An elderly man, not previously known to have chronic pancreatitis, presented with haematemesis and melaena which was endoscopically diagnosed as haemobilia. Retrograde cholangiopancreatography showed blood clot in both the common bile duct and the pancreatic duct and the computed tomographic scan appearances were those of gross calcific chronic pancreatitis. Despite active bleeding, it was not possible to demonstrate its source at angiography, thus precluding therapeutic embolization. Thirty six hours after commencing an infusion of somatostatin, repeat endoscopy showed no evidence of active or recent bleeding. The infusion was continued for 5 days during which time he had no further bleeding.

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Year:  1989        PMID: 2575252      PMCID: PMC2429303          DOI: 10.1136/pgmj.65.763.331

Source DB:  PubMed          Journal:  Postgrad Med J        ISSN: 0032-5473            Impact factor:   2.401


  11 in total

1.  Fatal gastrointestinal hemorrhage due to chronic relapsing pancreatitis; report of two cases, one with abscess and one with pseudocyst formation.

Authors:  R BREITENECKER
Journal:  N Engl J Med       Date:  1959-06-04       Impact factor: 91.245

2.  Rupture of a splenic artery aneurysm into the pancreatic duct.

Authors:  J Bowers; P R Koehler; S P Hammar; J A Nelson; K G Tolman
Journal:  Gastroenterology       Date:  1976-06       Impact factor: 22.682

3.  Massive gastrointestinal hemorrhage into the pancreatic duct - diagnosed by duodenoscopy and ERCP.

Authors:  W Rösch; O Schaffner; P Frühmorgen; H Koch
Journal:  Endoscopy       Date:  1977-05       Impact factor: 10.093

4.  Hemobilia: pancreatic pseudocyst hemorrhage demonstrated by endoscopy and arteriography.

Authors:  B B Brintnall; W W Laidlaw; J P Papp
Journal:  Am J Dig Dis       Date:  1974-02

5.  Massive hemorrhage from the celiac axis in pancreatitis.

Authors:  L M Schecter; H E Gordon; E Passaro
Journal:  Am J Surg       Date:  1974-08       Impact factor: 2.565

6.  Effect of somatostatin on splanchnic hemodynamics in patients with cirrhosis of the liver and in normal subjects.

Authors:  G E Sonnenberg; U Keller; A Perruchoud; D Burckhardt; K Gyr
Journal:  Gastroenterology       Date:  1981-03       Impact factor: 22.682

7.  A prospective randomised controlled clinical trial comparing somatostatin and vasopressin in controlling acute variceal haemorrhage.

Authors:  S A Jenkins; J N Baxter; W Corbett; P Devitt; J Ware; R Shields
Journal:  Br Med J (Clin Res Ed)       Date:  1985-01-26

8.  Effects of somatostatin on the exocrine pancreas and the release of duodenal hormones.

Authors:  S Raptis; W Schlegel; E Lehmann; H C Dollinger; C Zoupas
Journal:  Metabolism       Date:  1978-09       Impact factor: 8.694

9.  Visceral vessel erosion associated with pancreatitis. Case reports and a review of the literature.

Authors:  T R Gadacz; D Trunkey; R F Kieffer
Journal:  Arch Surg       Date:  1978-12

10.  [Dosage dependence of the effect of somatostatin on human splanchnic blood flow].

Authors:  U Keller; G E Sonnenberg; L Kayasseh; K Gyr; A Perruchoud
Journal:  Schweiz Med Wochenschr       Date:  1979-04-21
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  1 in total

Review 1.  Hemobilia.

Authors:  Marcus W Chin; Robert Enns
Journal:  Curr Gastroenterol Rep       Date:  2010-04
  1 in total

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