Literature DB >> 25751122

Downstream processing and chromatography based analytical methods for production of vaccines, gene therapy vectors, and bacteriophages.

Petra Kramberger1, Lidija Urbas, Aleš Štrancar.   

Abstract

Downstream processing of nanoplexes (viruses, virus-like particles, bacteriophages) is characterized by complexity of the starting material, number of purification methods to choose from, regulations that are setting the frame for the final product and analytical methods for upstream and downstream monitoring. This review gives an overview on the nanoplex downstream challenges and chromatography based analytical methods for efficient monitoring of the nanoplex production.

Keywords:  CIM monolithic column; DSP; PAT; USP; VLP; bacteriophage; gene therapy vector; purification; vaccine; virus

Mesh：

Substances：

Year:  2015        PMID： 25751122      PMCID： PMC4514237          DOI： 10.1080/21645515.2015.1009817

Source DB:  PubMed          Journal:  Hum Vaccin Immunother        ISSN： 2164-5515            Impact factor:   3.452


  59 in total

1.  An improved anion-exchange HPLC method for the detection and purification of adenoviral particles.

Authors:  F Blanche; B Cameron; A Barbot; L Ferrero; T Guillemin; S Guyot; S Somarriba; D Bisch
Journal:  Gene Ther       Date:  2000-06       Impact factor: 5.250

2.  Purification of infective baculoviruses by monoliths.

Authors:  Petra Gerster; Eva-Maria Kopecky; Nikolaus Hammerschmidt; Miriam Klausberger; Florian Krammer; Reingard Grabherr; Christa Mersich; Lidija Urbas; Petra Kramberger; Tina Paril; Matthias Schreiner; Katharina Nöbauer; Ebrahim Razzazi-Fazeli; Alois Jungbauer
Journal:  J Chromatogr A       Date:  2013-03-25       Impact factor: 4.759

3.  Purification of Vero cell derived live replication deficient influenza A and B virus by ion exchange monolith chromatography.

Authors:  Marko Banjac; Elisabeth Roethl; Franz Gelhart; Petra Kramberger; Barbara Lah Jarc; Marko Jarc; Aleš Strancar; Thomas Muster; Matjaž Peterka
Journal:  Vaccine       Date:  2014-03-12       Impact factor: 3.641

4.  Optimization of lytic phage manufacturing in bioreactor using monolithic supports.

Authors:  Franc Smrekar; Mateja Ciringer; Janez Jančar; Peter Raspor; Aleš Štrancar; Aleš Podgornik
Journal:  J Sep Sci       Date:  2011-06-06       Impact factor: 3.645

5.  Gradient optimization principles in reversed-phase high-performance liquid chromatography and the separation of influenza virus components.

Authors:  M A Phelan; K A Cohen
Journal:  J Chromatogr       Date:  1983-08-26

6.  Development and application of a reversed-phase high-performance liquid chromatographic method for quantitation and characterization of a Chikungunya virus-like particle vaccine.

Authors:  Anastasija Shytuhina; Pavlo Pristatsky; Jian He; Danilo R Casimiro; Richard M Schwartz; Van M Hoang; Sha Ha
Journal:  J Chromatogr A       Date:  2014-06-19       Impact factor: 4.759

7.  Improving stability of virus-like particles by ion-exchange chromatographic supports with large pore size: advantages of gigaporous media beyond enhanced binding capacity.

Authors:  Mengran Yu; Yan Li; Songping Zhang; Xiunan Li; Yanli Yang; Yi Chen; Guanghui Ma; Zhiguo Su
Journal:  J Chromatogr A       Date:  2014-01-18       Impact factor: 4.759

8.  Particle quantification of influenza viruses by high performance liquid chromatography.

Authors:  Julia Transfiguracion; Aziza P Manceur; Emma Petiot; Christine M Thompson; Amine A Kamen
Journal:  Vaccine       Date:  2014-11-21       Impact factor: 3.641

9.  Validation of a high-performance liquid chromatographic assay for the quantification of adenovirus type 5 particles.

Authors:  J Transfiguracion; A Bernier; N Arcand; P Chahal; A Kamen
Journal:  J Chromatogr B Biomed Sci Appl       Date:  2001-09-25

10.  Isolation of influenza viral proteins by size-exclusion and ion-exchange high-performance liquid chromatography: the influence of conditions on separation.

Authors:  D H Calam; J Davidson
Journal:  J Chromatogr       Date:  1984-07-27
View more
  12 in total

1.  The Superiority of Sucrose Cushion Centrifugation to Ultrafiltration and PEGylation in Generating High-Titer Lentivirus Particles and Transducing Stem Cells with Enhanced Efficiency.

Authors:  Mahdi Eskandarian Boroujeni; Mossa Gardaneh
Journal:  Mol Biotechnol       Date:  2018-03       Impact factor: 2.695

2.  Highly Efficient Purification of Recombinant VSV-∆G-Spike Vaccine against SARS-CoV-2 by Flow-Through Chromatography.

Authors:  Elad Lerer; Ziv Oren; Yaron Kafri; Yaakov Adar; Einat Toister; Lilach Cherry; Edith Lupu; Arik Monash; Rona Levy; Eyal Dor; Eyal Epstein; Lilach Levin; Meni Girshengorn; Niva Natan; Ran Zichel; Arik Makovitzki
Journal:  BioTech (Basel)       Date:  2021-10-12

3.  Evaluation of Host Cell Impurity Effects on the Performance of Sterile Filtration Processes for Therapeutic Viruses.

Authors:  Evan Wright; Karina Kawka; Maria Fe C Medina; David R Latulippe
Journal:  Membranes (Basel)       Date:  2022-03-24

4.  At-line multi-angle light scattering detector for faster process development in enveloped virus-like particle purification.

Authors:  Patricia Pereira Aguilar; Irene González-Domínguez; Tobias Amadeus Schneider; Francesc Gòdia; Laura Cervera; Alois Jungbauer
Journal:  J Sep Sci       Date:  2019-06-19       Impact factor: 3.614

Review 5.  Robust Approaches for the Production of Active Ingredient and Drug Product for Human Phage Therapy.

Authors:  Michele Mutti; Lorenzo Corsini
Journal:  Front Microbiol       Date:  2019-10-08       Impact factor: 5.640

Review 6.  Engineering DNA vaccines against infectious diseases.

Authors:  Jihui Lee; Shreedevi Arun Kumar; Yong Yu Jhan; Corey J Bishop
Journal:  Acta Biomater       Date:  2018-08-31       Impact factor: 8.947

Review 7.  Minerals in biology and medicine.

Authors:  Oliver W L Carter; Yingjian Xu; Peter J Sadler
Journal:  RSC Adv       Date:  2021-01-06       Impact factor: 3.361

8.  Genomic analysis and immune response in a murine mastitis model of vB_EcoM-UFV13, a potential biocontrol agent for use in dairy cows.

Authors:  Vinícius da Silva Duarte; Roberto Sousa Dias; Andrew M Kropinski; Stefano Campanaro; Laura Treu; Carolina Siqueira; Marcella Silva Vieira; Isabela da Silva Paes; Gabriele Rocha Santana; Franciele Martins; Josicelli Souza Crispim; André da Silva Xavier; Camila Geovana Ferro; Pedro M P Vidigal; Cynthia Canêdo da Silva; Sérgio Oliveira de Paula
Journal:  Sci Rep       Date:  2018-05-01       Impact factor: 4.379

Review 9.  Polysaccharide-based chromatographic adsorbents for virus purification and viral clearance.

Authors:  Guy-Alain Junter; Laurent Lebrun
Journal:  J Pharm Anal       Date:  2020-01-13

10.  Tangential Flow Filtration for the Concentration of Oncolytic Measles Virus: The Influence of Filter Properties and the Cell Culture Medium.

Authors:  Daniel Loewe; Tanja A Grein; Hauke Dieken; Tobias Weidner; Denise Salzig; Peter Czermak
Journal:  Membranes (Basel)       Date:  2019-11-29
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.