Literature DB >> 25750327

Operation for preservation of lung parenchyma in central lung cancer--in vivo and ex situ reimplantation techniques.

Christos Emmanouilides1, Stavros Tryfon2, Sofia Baka3, Hercules Titopoulos4, Albert Dager5, Dimitrios Filippou5.   

Abstract

BACKGROUND/AIM: Lobar reimplantation techniques enable the safe resection of lung cancer when pneumonectomy is not desirable or not feasible. We report our experience with this procedure. PATIENTS AND METHODS: Patients with difficult to resect upper/middle lobe non-small cell lung cancer were included. In situ reimplantation technique requires the reanastomosis of the pulmonary vein of the healthy lower lobe to the upper lobe stump; bench surgery reimplantation involves the ex vivo surgical treatment of the whole excised lung and subsequent reimplantation of the healthy remnant.
RESULTS: Nine patients with upper-middle lobe lung cancer underwent in situ reimplantation, mean age=70.7±4.2 years; 6 patients underwent ex situ resection, mean age=64.3±18.4 years. One obese patient succumbed due to thrombosis of the anastomosed pulmonary vein. One patient developed a stroke.
CONCLUSION: The procedure was in general well-tolerated and enables for curative resection of otherwise unresectable lung cancer. Copyright
© 2015 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

Entities:  

Keywords:  Non-small-cell lung cancer; autotransplantation; bench surgery; ex situ; in vivo; reimplantation

Mesh:

Year:  2015        PMID: 25750327

Source DB:  PubMed          Journal:  Anticancer Res        ISSN: 0250-7005            Impact factor:   2.480


  3 in total

1.  Extended resections for the treatment of patients with T4 stage IIIA non-small cell lung cancer (NSCLC) (T4N0-1M0) with or without cardiopulmonary bypass: a 15-year two-center experience.

Authors:  Dimitrios Filippou; Athanasios Kleontas; Vasilios Tentzeris; Christos Emmanouilides; Stavros Tryfon; Sofia Baka; Ioanna Filippou; Kostas Papagiannopoulos
Journal:  J Thorac Dis       Date:  2019-12       Impact factor: 2.895

2.  Lung autotransplantation for bronchial necrosis after radiotherapy: a case report.

Authors:  Yuya Nobori; Masaaki Sato; Mizuki Morota; Yoshikazu Shinohara; Daisuke Yoshida; Takahiro Karasaki; Kentaro Kitano; Jun Nakajima
Journal:  Surg Case Rep       Date:  2021-04-01

3.  [Efficacy of Lung Autotransplantation for Central Non-small Cell Lung Cancer].

Authors:  Yijun Mo; Lina Lin; Zhixin Li; Chenghua Zhong; Jun Yan; Jun Kuang; Guoxiong Yang; Jianhua Zhang
Journal:  Zhongguo Fei Ai Za Zhi       Date:  2020-08-20
  3 in total

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