Literature DB >> 25747657

Structural plasticity allows UCH37 to be primed by RPN13 or locked down by INO80G.

Xiang Chen1, Kylie J Walters2.   

Abstract

Two studies in this issue of Molecular Cell,VanderLinden et al. (2015) and Sahtoe et al. (2015),report crystal structures that define how deubiquitinating enzyme UCH37 is switched on or off by proteasome ubiquitin receptor RPN13 or chromatin remodeler component INO80G.
Copyright © 2015 Elsevier Inc. All rights reserved.

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Year:  2015        PMID： 25747657      PMCID： PMC6296220          DOI： 10.1016/j.molcel.2015.02.025

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  13 in total

1.  Structures of Rpn1 T1:Rad23 and hRpn13:hPLIC2 Reveal Distinct Binding Mechanisms between Substrate Receptors and Shuttle Factors of the Proteasome.

Authors:  Xiang Chen; Leah Randles; Ke Shi; Sergey G Tarasov; Hideki Aihara; Kylie J Walters
Journal:  Structure       Date:  2016-07-07       Impact factor: 5.006

2.  The Proteasome Ubiquitin Receptor hRpn13 and Its Interacting Deubiquitinating Enzyme Uch37 Are Required for Proper Cell Cycle Progression.

Authors:  Leah Randles; Ravi K Anchoori; Richard B S Roden; Kylie J Walters
Journal:  J Biol Chem       Date:  2016-02-23       Impact factor: 5.157

Review 3.  Gates, Channels, and Switches: Elements of the Proteasome Machine.

Authors:  Daniel Finley; Xiang Chen; Kylie J Walters
Journal:  Trends Biochem Sci       Date:  2015-11-28       Impact factor: 13.807

Review 4.  Meddling with Fate: The Proteasomal Deubiquitinating Enzymes.

Authors:  Stefanie A H de Poot; Geng Tian; Daniel Finley
Journal:  J Mol Biol       Date:  2017-10-05       Impact factor: 5.469

5.  Structure of hRpn10 Bound to UBQLN2 UBL Illustrates Basis for Complementarity between Shuttle Factors and Substrates at the Proteasome.

Authors:  Xiang Chen; Danielle L Ebelle; Brandon J Wright; Vinidhra Sridharan; Evan Hooper; Kylie J Walters
Journal:  J Mol Biol       Date:  2019-01-18       Impact factor: 5.469

6.  Cryo-EM Reveals Unanchored M1-Ubiquitin Chain Binding at hRpn11 of the 26S Proteasome.

Authors:  Xiang Chen; Zachary Dorris; Dan Shi; Rick K Huang; Htet Khant; Tara Fox; Natalia de Val; Dewight Williams; Ping Zhang; Kylie J Walters
Journal:  Structure       Date:  2020-08-11       Impact factor: 5.006

7.  Development and preclinical validation of a novel covalent ubiquitin receptor Rpn13 degrader in multiple myeloma.

Authors:  Yan Song; Paul M C Park; Lei Wu; Arghya Ray; Sarah Picaud; Deyao Li; Virangika K Wimalasena; Ting Du; Panagis Filippakopoulos; Kenneth C Anderson; Jun Qi; Dharminder Chauhan
Journal:  Leukemia       Date:  2019-04-08       Impact factor: 11.528

Review 8.  The emerging role of deubiquitinating enzymes in genomic integrity, diseases, and therapeutics.

Authors:  Mingjing He; Zhuan Zhou; Anil A Shah; Haojing Zou; Jin Tao; Qianming Chen; Yong Wan
Journal:  Cell Biosci       Date:  2016-12-20       Impact factor: 7.133

9.  Structure of the Rpn13-Rpn2 complex provides insights for Rpn13 and Uch37 as anticancer targets.

Authors:  Xiuxiu Lu; Urszula Nowicka; Vinidhra Sridharan; Fen Liu; Leah Randles; David Hymel; Marzena Dyba; Sergey G Tarasov; Nadya I Tarasova; Xue Zhi Zhao; Jun Hamazaki; Shigeo Murata; Terrence R Burke; Kylie J Walters
Journal:  Nat Commun       Date:  2017-06-09       Impact factor: 14.919

10.  Ubiquitin carboxyl-terminal hydrolase isozyme L5 inhibits human glioma cell migration and invasion via downregulating SNRPF.

Authors:  Jiafeng Ge; Weiwei Hu; Hui Zhou; Juan Yu; Chongran Sun; Weilin Chen
Journal:  Oncotarget       Date:  2017-12-07
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