Literature DB >> 2574594

Failure of terfenadine in relieving the pruritus of atopic dermatitis.

J Berth-Jones1, R A Graham-Brown.   

Abstract

We report the results of a double-blind, placebo-controlled, cross-over study of terfenadine 120 mg twice daily for pruritus in atopic dermatitis. Twenty-eight subjects with chronic atopic dermatitis received both terfenadine 120 mg b.d. and placebo each for a period of 1 week. Response was recorded by the subjects using visual analogue scales for severity of pruritus twice daily for the last 4 days of each treatment phase. There was no benefit from terfenadine.

Entities:  

Mesh:

Substances:

Year:  1989        PMID: 2574594     DOI: 10.1111/j.1365-2133.1989.tb08196.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN: 0007-0963            Impact factor:   9.302


  14 in total

1.  Second-generation antihistamines: a comparative review.

Authors:  J W Slater; A D Zechnich; D G Haxby
Journal:  Drugs       Date:  1999-01       Impact factor: 9.546

Review 2.  Placebo effects on itch: a meta-analysis of clinical trials of patients with dermatological conditions.

Authors:  Antoinette I M van Laarhoven; Ineke M van der Sman-Mauriks; A Rogier T Donders; Mathilde C Pronk; Peter C M van de Kerkhof; Andrea W M Evers
Journal:  J Invest Dermatol       Date:  2014-12-01       Impact factor: 8.551

Review 3.  Pharmacokinetic optimisation of histamine H1-receptor antagonist therapy.

Authors:  F E Simons; K J Simons
Journal:  Clin Pharmacokinet       Date:  1991-11       Impact factor: 6.447

4.  Spontaneous scratching behaviour in DS-Nh mice as a possible model for pruritus in atopic dermatitis.

Authors:  T Yoshioka; I Hikita; M Asakawa; T Hirasawa; M Deguchi; T Matsutani; H Oku; T Horikawa; A Arimura
Journal:  Immunology       Date:  2006-07       Impact factor: 7.397

Review 5.  Management of atopic eczema. Joint Workshop of the British Association of Dermatologists and the Research Unit of the Royal College of Physicians of London.

Authors:  P M McHenry; H C Williams; E A Bingham
Journal:  BMJ       Date:  1995-04-01

Review 6.  Acrivastine. A review of its pharmacological properties and therapeutic efficacy in allergic rhinitis, urticaria and related disorders.

Authors:  R N Brogden; D McTavish
Journal:  Drugs       Date:  1991-06       Impact factor: 9.546

Review 7.  Recent advances in treatment strategies for atopic dermatitis.

Authors:  Thomas Christian Roos; Stefan Geuer; Sabine Roos; Harald Brost
Journal:  Drugs       Date:  2004       Impact factor: 9.546

Review 8.  Oral H1 antihistamines as monotherapy for eczema.

Authors:  Christian J Apfelbacher; Esther J van Zuuren; Zbys Fedorowicz; Aldrin Jupiter; Uwe Matterne; Elke Weisshaar
Journal:  Cochrane Database Syst Rev       Date:  2013-02-28

Review 9.  Pruritus: a practical approach.

Authors:  P J Greco; J Ende
Journal:  J Gen Intern Med       Date:  1992 May-Jun       Impact factor: 5.128

10.  Failure of terfenadine as an antipruritic agent in atopic dogs: results of a double-blinded, placebo-controlled study.

Authors:  D W Scott; W H Miller; S M Cayatte; G A Decker
Journal:  Can Vet J       Date:  1994-05       Impact factor: 1.008

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.