Literature DB >> 25727392

Phenprobamate dependence: a case report.

Bahadir Demir1, Yasemin Demir2, Ihsan Aksoy3, Osman Hasan Tahsin Kilic3, Volkan Gucyetmez3, Haluk A Savas3.   

Abstract

Phenprobamate (3-phenylpropylcarbamate) is a centrally acting muscle relaxant with mild sedative and anticonvulsant effects. Muscle relaxants can enhance and prolong the effect of narcotic drugs and enable to obtain same effect with a smaller amount of alcohol or illicit substance. Almost all of the centrally acting muscle relaxants have varying sedative effects on which their abuse potential mainly depends. Data related to abuse of carisoprodol, meprobamate, baclofen takes place in the literature. However, to our knowledge this is the first case report about abuse of and tolerance to phenprobamate. We aimed to attract attention to important points of prescribing drugs that have abuse potential like in our case who was using up to 16000 mg/day phenprobamate.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Dependence; Phenprobamate

Mesh:

Substances:

Year:  2015        PMID: 25727392     DOI: 10.1016/j.addbeh.2015.01.037

Source DB:  PubMed          Journal:  Addict Behav        ISSN: 0306-4603            Impact factor:   3.913


  2 in total

1.  Something old, something new: a successful case of meprobamate withdrawal.

Authors:  Alexander Owen James; Timothy R Nicholson; Robert Hill; Jennifer Bearn
Journal:  BMJ Case Rep       Date:  2016-02-29

2.  Metabolic engineering of Escherichia coli for de novo production of 3-phenylpropanol via retrobiosynthesis approach.

Authors:  Zhenning Liu; Xue Zhang; Dengwei Lei; Bin Qiao; Guang-Rong Zhao
Journal:  Microb Cell Fact       Date:  2021-06-27       Impact factor: 5.328

  2 in total

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