Literature DB >> 25723583

[The German Cartilage Registry (KnorpelRegister DGOU) for evaluation of surgical treatment for cartilage defects: experience after six months including first demographic data].

P Niemeyer1, K Schweigler1, B Grotejohann2, J Maurer2, P Angele3, M Aurich4, C Becher5, J Fay6, R Feil7, S Fickert3, J Fritz8, A Hoburg9, P Kreuz10, T Kolombe11, J Laskowski7, J Lützner12, S Marlovits13, P E Müller14, T Niethammer14, M Pietschmann14, K Ruhnau15, G Spahn16, T Tischer10, W Zinser17, D Albrecht18.   

Abstract

The German Cartilage Registry (KnorpelRegister DGOU) has been introduced in October 2013 and aims on the evaluation of patients who underwent cartilage repair for symptomatic cartilage defects. It represents a nation-wide cohort study which has been introduced by the working group "Tissue Regeneration" of the Germany Society of Orthopaedic Surgery and Traumatology and is technically based upon a web-based remote data entry (RDE) system. The present article describes first experiences with the registry including patient and treatment characteristics. Between October 2013 and April 2014, a total of 230 patients who had undergone surgical cartilage repair for symptomatic full-thickness cartilage defects of the knee has been included in the German Cartilage Registry from 23 cartilage repair centres. Mean age was 37.11 years (SD 13.61) and mean defect size was 3.68 cm(2) (SD 0.23). Since the introduction of the KnorpelRegister DGOU the total number of registered patients has increased steadily up to the most recent figure of 72 patients within one month. Patients were treated mainly according to the recommended therapies. The highest percentage in therapy is represented by the bone marrow stimulation techniques (55.02 %) as well as by the autologous chondrocyte transplantation (34.92 %). Unlike the patient collective in the majority of prospective randomised controlled trials, the patient population within the registry shows a high proportion of patients with accompanying pathologies, with an age of more than 50 years at the time of treatment and with unfavourably assessed accompanying pathologies such as an affection of the opposite cartilage surface or a previously resected meniscus. In summary, the technical platform and forms of documentation of the KnorpelRegister DGOU have proved to be very promising within the first six months. Unlike data from other clinical trials, the previous analysis of the patients' data and therapies reflects successfully the actual medical care situation of patients with cartilage defects of the knee joint. This analysis also provides new information on subgroups of patients that have not yet been recorded in the scientific literature. This will be part of the first analysis of clinical treatment data. An expansion of the KnorpelRegister DGOU to patients with cartilage defects of the ankle and hip joints is already decided upon and initialised. Georg Thieme Verlag KG Stuttgart · New York.

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Year:  2015        PMID: 25723583     DOI: 10.1055/s-0034-1383222

Source DB:  PubMed          Journal:  Z Orthop Unfall        ISSN: 1864-6697            Impact factor:   0.923


  7 in total

Review 1.  Chondral and osteochondral operative treatment in early osteoarthritis.

Authors:  Peter Angele; Philipp Niemeyer; Matthias Steinwachs; Giuseppe Filardo; Andreas H Gomoll; Elizaveta Kon; Johannes Zellner; Henning Madry
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2016-02-27       Impact factor: 4.342

2.  The German Arthroscopy Registry (DART).

Authors:  Ralf Mueller-Rath; Oliver Miltner; Alfred Hochrein; Philipp Niemeyer
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2017-09-18       Impact factor: 4.342

3.  [Surgical treatment of focal cartilage defects in the knee : Indications, techniques, modifications and results].

Authors:  S Anders; J Grifka
Journal:  Orthopade       Date:  2022-02       Impact factor: 1.087

Review 4.  The First Report of the International Cartilage Regeneration and Joint Preservation Society's Global Registry.

Authors:  Leela C Biant; Caitlin W Conley; Michael J McNicholas
Journal:  Cartilage       Date:  2020-02-19       Impact factor: 3.117

5.  A Registry for Evaluation of Efficiency and Safety of Surgical Treatment of Cartilage Defects: The German Cartilage Registry (KnorpelRegister DGOU).

Authors:  Julia Maurer; Birgit Grotejohann; Carolin Jenkner; Carla Schneider; Thomas Flury; Adrian Tassoni; Peter Angele; Jürgen Fritz; Dirk Albrecht; Philipp Niemeyer
Journal:  JMIR Res Protoc       Date:  2016-06-29

6.  Autologous chondrocyte implantation combined with anterior cruciate ligament reconstruction: similar short-term results in comparison with isolated cartilage repair in ligament intact joints.

Authors:  Julian Mehl; Matthias Feucht; Andrea Achtnich; Andreas B Imhoff; Philipp Niemeyer; Peter Angele; Wolfgang Zinser; Gunter Spahn; Ingo Loer; Heino Kniffler; Gunnar Schauf; Andreas Schmitt
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2021-10-09       Impact factor: 4.114

7.  The German Arthroscopy Registry DART: what has happened after 5 years?

Authors:  Maximilian Hinz; Christoph Lutter; Ralf Mueller-Rath; Philipp Niemeyer; Oliver Miltner; Thomas Tischer
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2022-09-25       Impact factor: 4.114

  7 in total

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