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Literature DB >> 25712398

Two new stemphol sulfates from the mangrove endophytic fungus Stemphylium sp. 33231.

Xue-Ming Zhou¹, Cai-Juan Zheng¹, Guang-Ying Chen¹, Xiao-Ping Song¹, Chang-Ri Han¹, Xiong-Zhao Tang¹, Rui-Jie Liu¹, Li-Lian Ren¹.

Abstract

Two new stemphol sulfates, stemphol A (1) and stemphol B (2), along with known compound stemphol (3) were isolated from the EtOAc extract of the fermentation of an endophytic Stemphylium sp. 33231. The structures of these compounds were elucidated on the basis of spectroscopic analysis. The isolated compounds exhibited potent antibacterial activities against six terrestrial pathogenic bacteria with MIC values of 0.6-10 μg ml(-1). The inhibitory activities of all compounds against five cancer cell lines were evaluated.

Entities: Chemical Disease Species

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Year: 2015 PMID： 25712398 DOI： 10.1038/ja.2015.16

Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649

10 in total

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6. Natural occurrence of fungi and fungal metabolites in moldy tomatoes.

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7. Antibacterial α-pyrone derivatives from a mangrove-derived fungus Stemphylium sp. 33231 from the South China Sea.

Authors: Xue-Ming Zhou; Cai-Juan Zheng; Xiao-Ping Song; Chang-Ri Han; Wen-Hao Chen; Guang-Ying Chen
Journal: J Antibiot (Tokyo) Date: 2014-02-19 Impact factor: 2.649

8. Bioactive metabolites from the endophytic fungus Stemphylium globuliferum isolated from Mentha pulegium.

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9. Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines.

Authors: D A Scudiero; R H Shoemaker; K D Paull; A Monks; S Tierney; T H Nofziger; M J Currens; D Seniff; M R Boyd
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10. Anticancer effect of altersolanol A, a metabolite produced by the endophytic fungus Stemphylium globuliferum, mediated by its pro-apoptotic and anti-invasive potential via the inhibition of NF-κB activity.

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