Literature DB >> 25711317

Why START? Reflections that led to the conduct of this large long-term strategic HIV trial.

Jens Lundgren, Abdel Babiker, Fred Gordin, Sean Emery, Gerd Fätkenheuer, Jean-Michel Molina, Robin Wood, James D Neaton.   

Abstract

Entities:  

Keywords:  CD4-guided ART; HIV; START trial; antiretroviral therapy; when to start

Mesh：

Substances：

Year:  2015        PMID： 25711317      PMCID： PMC4347998          DOI： 10.1111/hiv.12227

Source DB:  PubMed          Journal:  HIV Med        ISSN： 1464-2662            Impact factor:   3.180


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  25 in total

1.  Regulatory impediments jeopardizing the conduct of clinical trials in Europe funded by the National Institutes of Health.

Authors:  James D Neaton; Abdel Babiker; Mark Bohnhorst; Janet Darbyshire; Eileen Denning; Arnie Frishman; Jesper Grarup; Gregg Larson; Jens Lundgren
Journal:  Clin Trials       Date:  2010-08-20       Impact factor: 2.486

2.  Timing of HAART initiation and clinical outcomes in human immunodeficiency virus type 1 seroconverters.

Authors: 
Journal:  Arch Intern Med       Date:  2011-09-26

Review 3.  Anti-inflammatory therapies for cardiovascular disease.

Authors:  Paul M Ridker; Thomas F Lüscher
Journal:  Eur Heart J       Date:  2014-05-26       Impact factor: 29.983

4.  Prevention of HIV-1 infection with early antiretroviral therapy.

Authors:  Myron S Cohen; Ying Q Chen; Marybeth McCauley; Theresa Gamble; Mina C Hosseinipour; Nagalingeswaran Kumarasamy; James G Hakim; Johnstone Kumwenda; Beatriz Grinsztejn; Jose H S Pilotto; Sheela V Godbole; Sanjay Mehendale; Suwat Chariyalertsak; Breno R Santos; Kenneth H Mayer; Irving F Hoffman; Susan H Eshleman; Estelle Piwowar-Manning; Lei Wang; Joseph Makhema; Lisa A Mills; Guy de Bruyn; Ian Sanne; Joseph Eron; Joel Gallant; Diane Havlir; Susan Swindells; Heather Ribaudo; Vanessa Elharrar; David Burns; Taha E Taha; Karin Nielsen-Saines; David Celentano; Max Essex; Thomas R Fleming
Journal:  N Engl J Med       Date:  2011-07-18       Impact factor: 91.245

Review 5.  Structured treatment interruptions (STI) in chronic suppressed HIV infection in adults.

Authors:  N P Pai; J P Tulsky; J Lawrence; J M Colford; A L Reingold
Journal:  Cochrane Database Syst Rev       Date:  2005-10-19

6.  Higher levels of CRP, D-dimer, IL-6, and hyaluronic acid before initiation of antiretroviral therapy (ART) are associated with increased risk of AIDS or death.

Authors:  David R Boulware; Katherine Huppler Hullsiek; Camille E Puronen; Adam Rupert; Jason V Baker; Martyn A French; Paul R Bohjanen; Richard M Novak; James D Neaton; Irini Sereti
Journal:  J Infect Dis       Date:  2011-06-01       Impact factor: 5.226

7.  CD4+ count-guided interruption of antiretroviral treatment.

Authors:  W M El-Sadr; J D Lundgren; J D Neaton; F Gordin; D Abrams; R C Arduino; A Babiker; W Burman; N Clumeck; C J Cohen; D Cohn; D Cooper; J Darbyshire; S Emery; G Fätkenheuer; B Gazzard; B Grund; J Hoy; K Klingman; M Losso; N Markowitz; J Neuhaus; A Phillips; C Rappoport
Journal:  N Engl J Med       Date:  2006-11-30       Impact factor: 91.245

8.  The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis.

Authors:  Daniel I Swerdlow; Michael V Holmes; Karoline B Kuchenbaecker; Jorgen E L Engmann; Tina Shah; Reecha Sofat; Yiran Guo; Christina Chung; Anne Peasey; Roman Pfister; Simon P Mooijaart; Helen A Ireland; Maarten Leusink; Claudia Langenberg; Ka Wah Li; Jutta Palmen; Philip Howard; Jackie A Cooper; Fotios Drenos; John Hardy; Michael A Nalls; Yun Rose Li; Gordon Lowe; Marlene Stewart; Suzette J Bielinski; Julian Peto; Nicholas J Timpson; John Gallacher; Malcolm Dunlop; Richard Houlston; Ian Tomlinson; Ioanna Tzoulaki; Jian'an Luan; Jolanda M A Boer; Nita G Forouhi; N Charlotte Onland-Moret; Yvonne T van der Schouw; Renate B Schnabel; Jaroslav A Hubacek; Ruzena Kubinova; Migle Baceviciene; Abdonas Tamosiunas; Andrzej Pajak; Roman Topor-Madry; Sofia Malyutina; Damiano Baldassarre; Bengt Sennblad; Elena Tremoli; Ulf de Faire; Luigi Ferrucci; Stefania Bandenelli; Toshiko Tanaka; James F Meschia; Andrew Singleton; Gerjan Navis; Irene Mateo Leach; Stephan J L Bakker; Ron T Gansevoort; Ian Ford; Stephen E Epstein; Mary Susan Burnett; Joe M Devaney; J Wouter Jukema; Rudi G J Westendorp; Gert Jan de Borst; Yolanda van der Graaf; Pim A de Jong; Anke-Hilse Mailand-van der Zee; Olaf H Klungel; Anthonius de Boer; Pieter A Doevendans; Jeffrey W Stephens; Charles B Eaton; Jennifer G Robinson; JoAnn E Manson; F Gerry Fowkes; Timonthy M Frayling; Jackie F Price; Peter H Whincup; Richard W Morris; Debbie A Lawlor; George Davey Smith; Yoav Ben-Shlomo; Susan Redline; Leslie A Lange; Meena Kumari; Nick J Wareham; W M Monique Verschuren; Emelia J Benjamin; John C Whittaker; Anders Hamsten; Frank Dudbridge; J A Chris Delaney; Andrew Wong; Diana Kuh; Rebecca Hardy; Berta Almoguera Castillo; John J Connolly; Pim van der Harst; Eric J Brunner; Michael G Marmot; Christina L Wassel; Steve E Humphries; Philippa J Talmud; Mika Kivimaki; Folkert W Asselbergs; Mikhail Voevoda; Martin Bobak; Hynek Pikhart; James G Wilson; Hakon Hakonarson; Alex P Reiner; Brendan J Keating; Naveed Sattar; Aroon D Hingorani; Juan Pablo Casas
Journal:  Lancet       Date:  2012-03-14       Impact factor: 79.321

9.  When to initiate combined antiretroviral therapy to reduce mortality and AIDS-defining illness in HIV-infected persons in developed countries: an observational study.

Authors:  Lauren E Cain; Roger Logan; James M Robins; Jonathan A C Sterne; Caroline Sabin; Loveleen Bansi; Amy Justice; Joseph Goulet; Ard van Sighem; Frank de Wolf; Heiner C Bucher; Viktor von Wyl; Anna Esteve; Jordi Casabona; Julia del Amo; Santiago Moreno; Remonie Seng; Laurence Meyer; Santiago Perez-Hoyos; Roberto Muga; Sara Lodi; Emilie Lanoy; Dominique Costagliola; Miguel A Hernan
Journal:  Ann Intern Med       Date:  2011-04-19       Impact factor: 25.391

10.  Markers of inflammation and activation of coagulation are associated with anaemia in antiretroviral-treated HIV disease.

Authors:  Álvaro H Borges; Jeffrey I Weitz; Gary Collins; Jason V Baker; Yves Lévy; Richard T Davey; Andrew N Phillips; James D Neaton; Jens D Lundgren; Steven G Deeks
Journal:  AIDS       Date:  2014-07-31       Impact factor: 4.177
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  8 in total

1.  Evaluating the Impact of a HIV Low-Risk Express Care Task-Shifting Program: A Case Study of the Targeted Learning Roadmap.

Authors:  Linh Tran; Constantin T Yiannoutsos; Beverly S Musick; Kara K Wools-Kaloustian; Abraham Siika; Sylvester Kimaiyo; Mark J van der Laan; Maya Petersen
Journal:  Epidemiol Methods       Date:  2016-11-10

2.  Risk of Suicidal Behavior With Use of Efavirenz: Results from the Strategic Timing of Antiretroviral Treatment Trial.

Authors:  Alejandro Arenas-Pinto; Birgit Grund; Shweta Sharma; Esteban Martinez; Nathan Cummins; Julie Fox; Karin L Klingman; Dalibor Sedlacek; Simon Collins; Patricia M Flynn; William M Chasanov; Eynat Kedem; Christine Katlama; Juan Sierra-Madero; Claudia Afonso; Pim Brouwers; David A Cooper
Journal:  Clin Infect Dis       Date:  2018-07-18       Impact factor: 9.079

Review 3.  Serious Non-AIDS Conditions in HIV: Benefit of Early ART.

Authors:  Jens D Lundgren; Alvaro H Borges; James D Neaton
Journal:  Curr HIV/AIDS Rep       Date:  2018-04       Impact factor: 5.071

4.  Challenges, successes and patterns of enrolment in the INSIGHT Strategic Timing of AntiRetroviral Treatment (START) trial.

Authors:  J Grarup; C Rappoport; N W Engen; C Carey; F Hudson; E Denning; S Sharma; E Florence; M J Vjecha
Journal:  HIV Med       Date:  2015-04       Impact factor: 3.180

5.  Meeting the WHO 90% target: antiretroviral treatment efficacy in Poland is associated with baseline clinical patient characteristics.

Authors:  Milosz Parczewski; Ewa Siwak; Magdalena Leszczyszyn-Pynka; Iwona Cielniak; Ewa Burkacka; Piotr Pulik; Adam Witor; Karolina Muller; Ewelina Zasik; Anna Grzeszczuk; Maria Jankowska; Małgorzata Lemańska; Anita Olczak; Edyta Grąbczewska; Aleksandra Szymczak; Jacek Gąsiorowski; Bartosz Szetela; Monika Bociąga-Jasik; Paweł Skwara; Magdalena Witak-Jędra; Elżbieta Jabłonowska; Kamila Wójcik-Cichy; Juliusz Kamerys; Małgorzata Janczarek; Dagny Krankowska; Tomasz Mikuła; Katarzyna Kozieł; Dariusz Bielec; Justyna Stempkowska; Aleksandra Kocbach; Wiesława Błudzin; Andrzej Horban
Journal:  J Int AIDS Soc       Date:  2017-07-17       Impact factor: 5.396

6.  The Presence of Human Immunodeficiency Virus-Associated Neurocognitive Disorders Is Associated With a Lower Adherence to Combined Antiretroviral Treatment.

Authors:  Susan Kamal; Isabella Locatelli; Gilles Wandeler; Asemaneh Sehhat; Olivier Bugnon; Melanie Metral; Renaud Du Pasquier; Klemens Gutbrod; Matthias Cavassini; Marie P Schneider
Journal:  Open Forum Infect Dis       Date:  2017-04-06       Impact factor: 3.835

7.  Cascade of care and factors associated with virological suppression among HIV-positive persons linked to care in the Test and Keep in Care (TAK) project.

Authors:  Justyna D Kowalska; Magdalena Ankiersztejn-Bartczak; Leah Shepherd; Amanda Mocroft
Journal:  Infection       Date:  2018-05-21       Impact factor: 3.553

8.  A study on the dynamics of temporary HIV treatment to assess the controversial outcomes of clinical trials: An in-silico approach.

Authors:  Emiliano Mancini; Rick Quax; Andrea De Luca; Sarah Fidler; Wolfgang Stohr; Peter M A Sloot
Journal:  PLoS One       Date:  2018-07-18       Impact factor: 3.240
  8 in total

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