INTRODUCTION: There is a strong association between obesity and gastroesophageal reflux disease (GERD). GERD-related questionnaires have been developed in order to objectify symptoms. However, none of them has been tested in obese population. PURPOSE: The purpose of this study is to evaluate if GERD score and GERD-Health-Related Quality of Life (HRQL) can reflect severity of the disease and screen obese patients for GERD preoperatively. GERD's impact on the quality of life of obese patients is being assessed with the use of EORTC-QLQ C30. PATIENTS- METHODS: Obese patients during their preoperative evaluation were recruited regardless of the presence of GERD symptoms. A targeted GERD symptom history was obtained. Patients completed GERD score, GERD-HRQL, and EORTC-QLQ C30, and then, a 24-h multichannel intraluminal impedance pHmetry (MIIpH) was conducted. RESULTS: Forty-seven consecutive obese patients with mean age 39.91 years and mean BMI 46.94 kg/m(2) were included in the study. GERD score and GERD-HRQL have a positive linear correlation with DeMeester score (p = 0.001 and p < 0.001, respectively). EORTC QLQ-C30 does not correlate with DeMeester score. CONCLUSIONS: GERD-related questionnaires could be used in obese population as preoperative screening tool for GERD. However, our results indicate that the quality of life of obese patients is not affected by the existence of GERD.
INTRODUCTION: There is a strong association between obesity and gastroesophageal reflux disease (GERD). GERD-related questionnaires have been developed in order to objectify symptoms. However, none of them has been tested in obese population. PURPOSE: The purpose of this study is to evaluate if GERD score and GERD-Health-Related Quality of Life (HRQL) can reflect severity of the disease and screen obesepatients for GERD preoperatively. GERD's impact on the quality of life of obesepatients is being assessed with the use of EORTC-QLQ C30. PATIENTS- METHODS:Obesepatients during their preoperative evaluation were recruited regardless of the presence of GERD symptoms. A targeted GERD symptom history was obtained. Patients completed GERD score, GERD-HRQL, and EORTC-QLQ C30, and then, a 24-h multichannel intraluminal impedance pHmetry (MIIpH) was conducted. RESULTS: Forty-seven consecutive obesepatients with mean age 39.91 years and mean BMI 46.94 kg/m(2) were included in the study. GERD score and GERD-HRQL have a positive linear correlation with DeMeester score (p = 0.001 and p < 0.001, respectively). EORTC QLQ-C30 does not correlate with DeMeester score. CONCLUSIONS: GERD-related questionnaires could be used in obese population as preoperative screening tool for GERD. However, our results indicate that the quality of life of obesepatients is not affected by the existence of GERD.
Authors: Peter J Kahrilas; Nicholas J Shaheen; Michael F Vaezi; Stephen W Hiltz; Edgar Black; Irvin M Modlin; Steve P Johnson; John Allen; Joel V Brill Journal: Gastroenterology Date: 2008-10 Impact factor: 22.682
Authors: Carlos A S Madalosso; Richard R Gurski; Sidia M Callegari-Jacques; Daniel Navarini; Victor Thiesen; Fernando Fornari Journal: Ann Surg Date: 2010-02 Impact factor: 12.969
Authors: Alexandra Argyrou; Evangelia Legaki; Christos Koutserimpas; Maria Gazouli; Ioannis Papaconstantinou; George Gkiokas; George Karamanolis Journal: World J Clin Cases Date: 2018-08-16 Impact factor: 1.337