Doulami Georgia1, Triantafyllou Stamatina2, Natoudi Maria3, Albanopoulos Konstantinos3, Filis Konstantinos4, Leandros Emmanouil3, Zografos Georgios4, Theodorou Dimitrios2. 1. Foregut Department, 1st Propaedeutic Surgical Department, Hippokration General Hospital of Athens, National and Kapodistrian University of Athens, 114 Vas Sofias Av, 115 27, Athens, Greece. tzinagb@yahoo.gr. 2. Foregut Department, 1st Propaedeutic Surgical Department, Hippokration General Hospital of Athens, National and Kapodistrian University of Athens, 114 Vas Sofias Av, 115 27, Athens, Greece. 3. Bariatric Surgery Department, 1st Propaedeutic Surgical Department, Hippokration General Hospital of Athens, National and Kapodistrian University of Athens, Athens, Greece. 4. 1st Propaedeutic Surgical Department, Hippokration General Hospital of Athens, National and Kapodistrian University of Athens, Athens, Greece.
Abstract
INTRODUCTION: It is not yet clear if laparoscopic sleeve gastrectomy (LSG) causes newly onset gastroesophageal reflux (GERD) or worsens already existing GERD. This is due to the absence of prospective studies using objective assessment measures of GERD such as pH monitoring. Our study aims at assessing GERD 1-year post-LSG procedure for obesity. MATERIALS AND METHODS: Twelve asymptomatic obese patients were studied prospectively by using 24-h multichannel intraluminal impedance-pHmetry (MIIpH) pre- and 12 months post-LSG. RESULTS: Of patients' 1-year post-LSG, 83.33 % of patients' suffer from GERD (either newly onset or worsening of already existing) as indicated by abnormal DeMeester score. Mean DeMeester score 1-year post LSG was 47, almost 2.5 times higher than the preoperative score (p = 0.072). The percentage of total time with pH lower than four was statistically significant higher postoperatively (13.27 % vs 3.87 %, p = 0.048). CONCLUSION: This study is one of the few assessing GERD post-LSG by using 24-h MIIpH. The majority of patients suffer from GERD 12 months postoperatively, implying that close postoperative monitor for GERD with the use of pH testing and upper gastrointestinal endoscopy in order to early diagnose GERD and identify possible mucosal injury and also a prophylactic proton pump inhibitor use may be of great importance.
INTRODUCTION: It is not yet clear if laparoscopic sleeve gastrectomy (LSG) causes newly onset gastroesophageal reflux (GERD) or worsens already existing GERD. This is due to the absence of prospective studies using objective assessment measures of GERD such as pH monitoring. Our study aims at assessing GERD 1-year post-LSG procedure for obesity. MATERIALS AND METHODS: Twelve asymptomatic obesepatients were studied prospectively by using 24-h multichannel intraluminal impedance-pHmetry (MIIpH) pre- and 12 months post-LSG. RESULTS: Of patients' 1-year post-LSG, 83.33 % of patients' suffer from GERD (either newly onset or worsening of already existing) as indicated by abnormal DeMeester score. Mean DeMeester score 1-year post LSG was 47, almost 2.5 times higher than the preoperative score (p = 0.072). The percentage of total time with pH lower than four was statistically significant higher postoperatively (13.27 % vs 3.87 %, p = 0.048). CONCLUSION: This study is one of the few assessing GERD post-LSG by using 24-h MIIpH. The majority of patients suffer from GERD 12 months postoperatively, implying that close postoperative monitor for GERD with the use of pH testing and upper gastrointestinal endoscopy in order to early diagnose GERD and identify possible mucosal injury and also a prophylactic proton pump inhibitor use may be of great importance.
Authors: Raul J Rosenthal; Alberto Aceves Diaz; Dag Arvidsson; Randal S Baker; Nicola Basso; Drake Bellanger; Camilo Boza; Haicam El Mourad; Michael France; Michel Gagner; Manoel Galvao-Neto; Kelvin D Higa; Jacques Himpens; Colleen M Hutchinson; Moises Jacobs; John O Jorgensen; Gregg Jossart; Muffazal Lakdawala; Ninh T Nguyen; David Nocca; Gerhard Prager; Alfons Pomp; Almino Cardoso Ramos; Raul J Rosenthal; Shashank Shah; Michel Vix; Alan Wittgrove; Natan Zundel Journal: Surg Obes Relat Dis Date: 2011-11-10 Impact factor: 4.734
Authors: David Benaiges; Antonio Más-Lorenzo; Albert Goday; José M Ramon; Juan J Chillarón; Juan Pedro-Botet; Juana A Flores-Le Roux Journal: World J Gastroenterol Date: 2015-11-07 Impact factor: 5.742
Authors: Jan S Burgerhart; Charlotte A I Schotborgh; Erik J Schoon; Johannes F Smulders; Paul C van de Meeberg; Peter D Siersema; André J P M Smout Journal: Obes Surg Date: 2014-09 Impact factor: 4.129
Authors: Givan F Paulus; Loes E G de Vaan; Froukje J Verdam; Nicole D Bouvy; Ton A W Ambergen; L W Ernest van Heurn Journal: Obes Surg Date: 2015-05 Impact factor: 4.129
Authors: Mario Musella; Mervyn Deitel; K S Kular; Miguel-A Carbajo; Karl P Rheinwalt; Chetan Parmar; Arun Prasad; Enrique Luque-de-Leon; Gurvinder Jammu; Roger Luciani; David Hargroder; Cesare Pereaglie; Jean Marc Chevallier Journal: Obes Surg Date: 2019-02 Impact factor: 4.129
Authors: L Ulas Biter; Michiel M A van Buuren; Guido H H Mannaerts; Jan A Apers; Martin Dunkelgrün; Guy H E J Vijgen Journal: Obes Surg Date: 2017-10 Impact factor: 4.129
Authors: Fabrizio Rebecchi; Marco E Allaix; Marco G Patti; Francisco Schlottmann; Mario Morino Journal: World J Gastroenterol Date: 2017-04-07 Impact factor: 5.742
Authors: Veeravich Jaruvongvanich; Reem Matar; Karthik Ravi; M Hassan Murad; Kornpong Vantanasiri; Nicha Wongjarupong; Patompong Ungprasert; Eric J Vargas; Daniel B Maselli; Larry J Prokop; Barham K Abu Dayyeh Journal: Clin Transl Gastroenterol Date: 2020-08 Impact factor: 4.396