Literature DB >> 25707708

Changes in non-opioid substitution treatment episodes for pharmaceutical opioids and heroin from 2002 to 2011.

S Nielsen1, A Roxburgh2, R Bruno3, N Lintzeris4, A Jefferson5, L Degenhardt2.   

Abstract

BACKGROUND: There has been a well-documented increase in the non-medical use of pharmaceutical opioids (PO) worldwide. However, there has been little detailed examination of treatment demand, or the characteristics of those presenting for treatment, particularly for treatments other than opioid substitution.
METHODS: Data from closed drug and alcohol treatment episodes from the Alcohol and Other Drug Treatment Services National Minimum Data Set (AODTS-NMDS, representing non-opioid substitution treatment) in Australia for 2002-2003 to 2010-2011 were examined. In the four jurisdictions where detailed data were available, episodes where heroin was the principal drug of concern were compared to episodes for the four most frequently reported pharmaceutical opioids (morphine, codeine, fentanyl and oxycodone).
RESULTS: In 2002-2003, most (93%) opioid treatment was related to heroin with seven percent of all opioid treatment episodes reporting a PO as the principal drug of concern. In 2010-2011, 20% of all opioid treatment episodes were attributed to POs. Distinct changes over time were observed for different opioids. There was an increase in the average age at the start of treatment for heroin and oxycodone episodes, and a reduction in the proportion of females for codeine episodes, with 67% in 2002-2003 compared with 44% in 2010-2011. Codeine and oxycodone episodes had the lowest current or past injection rates.
CONCLUSIONS: Clear differences were observed over time and between different opioids. Monitoring these emerging patterns will be important to inform treatment needs, particularly in light of different patterns of poly drug use, different routes of administration and changing demographic characteristics.
Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Codeine; Fentanyl; Oxycodone; Prescription opioid; Treatment

Mesh:

Substances:

Year:  2015        PMID: 25707708     DOI: 10.1016/j.drugalcdep.2015.02.004

Source DB:  PubMed          Journal:  Drug Alcohol Depend        ISSN: 0376-8716            Impact factor:   4.492


  4 in total

1.  An ecological study of the extent and factors associated with the use of prescription and over-the-counter codeine in Australia.

Authors:  Natasa Gisev; Suzanne Nielsen; Elena Cama; Briony Larance; Raimondo Bruno; Louisa Degenhardt
Journal:  Eur J Clin Pharmacol       Date:  2015-12-22       Impact factor: 2.953

2.  Development of a Brief Patient-Administered Screening Tool for Prescription Opioid Dependence for Primary Care Settings.

Authors:  Suzanne Nielsen; Louisa Picco; Gabrielle Campbell; Nicholas Lintzeris; Briony Larance; Michael Farrell; Louisa Degenhardt; Raimondo Bruno
Journal:  Pain Med       Date:  2020-02-01       Impact factor: 3.750

Review 3.  Opioid agonist treatment for people who are dependent on pharmaceutical opioids.

Authors:  Suzanne Nielsen; Wai Chung Tse; Briony Larance
Journal:  Cochrane Database Syst Rev       Date:  2022-09-05

4.  Misuse of Over the Counter and Prescription Only Medication by Adults Accessing Specialist Treatment Services in the UK: A Narrative Synthesis.

Authors:  Rosalind Gittins; Louise Missen; Ian Maidment
Journal:  Subst Abuse       Date:  2022-07-11
  4 in total

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