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Literature DB >> 2570701

Suppression of histamine-induced skin reactions by loratadine and cetirizine diHCl.

K Kontou-Fili¹, G Paleologos, M Herakleous.

Abstract

The skin reactivity to histamine was measured in 10 healthy and 10 atopic subjects after the ingestion of single doses of loratadine 10 mg, cetirizine diHCl 10 mg and placebo, in a double-blind cross-over randomized study. The anti-H1 effect of cetirizine diHCl proved to be significantly more rapid, more pronounced and longer lasting than that of loratadine.

Entities: Chemical

Mesh：

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Year: 1989 PMID： 2570701 DOI： 10.1007/BF00637746

Source DB: PubMed Journal: Eur J Clin Pharmacol ISSN： 0031-6970 Impact factor: 2.953

11 in total

1. Effect of cetirizine on mast cell-mediator release and cellular traffic during the cutaneous late-phase reaction.

Authors: E N Charlesworth; A Kagey-Sobotka; P S Norman; L M Lichtenstein
Journal: J Allergy Clin Immunol Date: 1989-05 Impact factor: 10.793

2. Inhibitory effect of cetirizine 2HCl on eosinophil migration in vivo.

Authors: R Fadel; N Herpin-Richard; J P Rihoux; E Henocq
Journal: Clin Allergy Date: 1987-07

3. Effect of an H1 blocker, chlorpheniramine, on inhalation tests with histamine and allergen in allergic asthma.

Authors: V T Popa
Journal: Chest Date: 1980-09 Impact factor: 9.410

4. Evaluation of the CNS properties of SCH 29851, a potential non-sedating antihistamine.

Authors: A Barnett; L C Iorio; W Kreutner; S Tozzi; H S Ahn; A Gulbenkian
Journal: Agents Actions Date: 1984-06

5. Comparative study of the peripheral and central effects of terfenadine and cetirizine 2 HCl.

Authors: J P Rihoux; P Dupont
Journal: Ann Allergy Date: 1987-09

6. Receptor effects of cetirizine.

Authors: S H Snyder; A M Snowman
Journal: Ann Allergy Date: 1987-12

7. Cetirizine inhibition of histamine-induced bronchospasm.

Authors: D P Tashkin; A Brik; H Gong
Journal: Ann Allergy Date: 1987-12

8. The effect of H1 and H2 blockade on cutaneous histamine response in man.

Authors: R P Harvey; A L Schocket
Journal: J Allergy Clin Immunol Date: 1980-02 Impact factor: 10.793

9. Antiallergic activity of loratadine, a non-sedating antihistamine.

Authors: W Kreutner; R W Chapman; A Gulbenkian; M I Siegel
Journal: Allergy Date: 1987-01 Impact factor: 13.146

10. Suppression of histamine-induced wheal response by loratadine (SCH 29851) over 28 days in man.

Authors: I J Roman; N Kassem; R P Gural; J Herron
Journal: Ann Allergy Date: 1986-10

7 in total

Review 1. Cetirizine. An updated review of its pharmacological properties and therapeutic efficacy.

Authors: J P Rihoux; S Mariz
Journal: Clin Rev Allergy Date: 1993

Review 2. Clinical pharmacology of new histamine H1 receptor antagonists.

Authors: F E Simons; K J Simons
Journal: Clin Pharmacokinet Date: 1999-05 Impact factor: 6.447

3. Idiopathic histaminergic angioedema without wheals: a case series of 31 patients.

Authors: C Faisant; I Boccon-Gibod; C Mansard; C Dumestre Perard; P Pralong; C Chatain; A Deroux; L Bouillet
Journal: Clin Exp Immunol Date: 2016-04-13 Impact factor: 4.330

Review 4. Cetirizine. A review of its pharmacological properties and clinical potential in allergic rhinitis, pollen-induced asthma, and chronic urticaria.

Authors: D M Campoli-Richards; M M Buckley; A Fitton
Journal: Drugs Date: 1990-11 Impact factor: 9.546