Literature DB >> 25700848

Predictors and Moderators of Clinical Outcomes in Adolescents with Severe Mental Disorders After an Assertive Community Treatment.

Sébastien Urben1, Vanessa Baier2, Gregory Mantzouranis3, Eva Pigois2, Caroline Graap2, Fabienne Dutoit2, Mélanie Cherix-Parchet4, Coralie Henz5, Aymeric Faucherand2, Esperanza Senent2, Laurent Holzer2.   

Abstract

Previous studies have shown that stressful life events (SLEs), gender, social functioning and pretreatment severity are some of the predictors and/or moderators of treatment outcome in psychiatric care. The current study explored the effect of these predictors and moderators on the treatment outcome related to assertive community treatment (ACT) proposed to young people with severe mental disorders. 98 patients were assessed for externalizing and emotional difficulties, at admission and then at discharge of an ACT. Analyses revealed significant improvements in terms of symptomatology. In particular, regression analyses showed that pretreatment severity is a significant predictor of the outcome on emotional symptoms and is moderated by SLE on the outcome on externalizing symptoms. Furthermore, higher social functioning proved to predict better outcome on externalizing symptoms. Our results further evidence that these factors can explain inter-individual differences in outcome related to ACT. The theoretical and clinical implications of these results are discussed.

Entities:  

Keywords:  Adolescents; Assertive community treatment; Moderation effect; Pretreatment severity; Psychiatric disorders; Stressful life events; Treatment outcome

Mesh:

Year:  2015        PMID: 25700848     DOI: 10.1007/s10578-015-0537-z

Source DB:  PubMed          Journal:  Child Psychiatry Hum Dev        ISSN: 0009-398X


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  2 in total

1.  Negative symptoms, anxiety, and depression as mechanisms of change of a 12-month trial of assertive community treatment as part of integrated care in patients with first- and multi-episode schizophrenia spectrum disorders (ACCESS I trial).

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Review 2.  The effect of youth assertive community treatment: a systematic PRISMA review.

Authors:  Richard Vijverberg; Robert Ferdinand; Aartjan Beekman; Berno van Meijel
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