Literature DB >> 25699291

Semantic Predications for Complex Information Needs in Biomedical Literature.

Delroy Cameron1, Ramakanth Kavuluru2, Olivier Bodenreider, Pablo N Mendes, Amit P Sheth, Krishnaprasad Thirunarayan.   

Abstract

Many complex information needs that arise in biomedical disciplines require exploring multiple documents in order to obtain information. While traditional information retrieval techniques that return a single ranked list of documents are quite common for such tasks, they may not always be adequate. The main issue is that ranked lists typically impose a significant burden on users to filter out irrelevant documents. Additionally, users must intuitively reformulate their search query when relevant documents have not been not highly ranked. Furthermore, even after interesting documents have been selected, very few mechanisms exist that enable document-to-document transitions. In this paper, we demonstrate the utility of assertions extracted from biomedical text (called semantic predications) to facilitate retrieving relevant documents for complex information needs. Our approach offers an alternative to query reformulation by establishing a framework for transitioning from one document to another. We evaluate this novel knowledge-driven approach using precision and recall metrics on the 2006 TREC Genomics Track.

Entities:  

Keywords:  background knowledge; literature-based discovery; question answering; semantic predications; text mining

Year:  2011        PMID: 25699291      PMCID: PMC4330970          DOI: 10.1109/BIBM.2011.23

Source DB:  PubMed          Journal:  IEEE Int Conf Bioinform Biomed Workshops


  7 in total

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Authors:  C Perez-Iratxeta; P Bork; M A Andrade
Journal:  Trends Biochem Sci       Date:  2001-09       Impact factor: 13.807

2.  Biomedical knowledge navigation by literature clustering.

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Journal:  J Biomed Inform       Date:  2006-08-05       Impact factor: 6.317

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Journal:  Nat Biotechnol       Date:  2009-06       Impact factor: 54.908

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Journal:  Perspect Biol Med       Date:  1988       Impact factor: 1.416

5.  Fish oil, Raynaud's syndrome, and undiscovered public knowledge.

Authors:  D R Swanson
Journal:  Perspect Biol Med       Date:  1986       Impact factor: 1.416

6.  Linking estrogen to Alzheimer's disease: an informatics approach.

Authors:  N R Smalheiser; D R Swanson
Journal:  Neurology       Date:  1996-09       Impact factor: 9.910

7.  HubMed: a web-based biomedical literature search interface.

Authors:  Alfred D Eaton
Journal:  Nucleic Acids Res       Date:  2006-07-01       Impact factor: 16.971

  7 in total
  1 in total

1.  A graph-based recovery and decomposition of Swanson's hypothesis using semantic predications.

Authors:  Delroy Cameron; Olivier Bodenreider; Hima Yalamanchili; Tu Danh; Sreeram Vallabhaneni; Krishnaprasad Thirunarayan; Amit P Sheth; Thomas C Rindflesch
Journal:  J Biomed Inform       Date:  2012-09-28       Impact factor: 6.317

  1 in total

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