Literature DB >> 25693666

Evaluation of whole body Ultralow-Dose CT for the assessment of ventriculoperitoneal shunt complications: an experimental ex-vivo study in a swine model.

Ahmed Othman1, Hussam A Hamou, Rastislav Pjontek, Saif Afat, Hans Clusmann, Martin Wiesmann, Marc A Brockmann.   

Abstract

OBJECTIVE: To evaluate the suitability of whole body Ultralow-dose CT (ULD-CT) as a diagnostic tool for the evaluation of ventriculoperitoneal shunt (VP-shunt) complications with special regards to radiation dose and image quality.
METHODS: Fourteen VP-shunts were implanted in 7 swine cadavers (weight: 55-70 kg). Twenty-two mechanical complications (extracranial and extraperitoneal malpositioning, breakages, disconnections) were induced in nine VP-shunts. Ten ULD-CT scans with different parameters (tube voltage: 80, 100, 120 kV; tube current: 20 or 50 mAs; Pitch (P): 1 or 1.5) were acquired; the combination of 120 kV and 50 mAs was omitted. Radiation dose estimation, blinded readings, and quantitative and qualitative assessment of the CT-data were performed.
RESULTS: Effective radiation doses varied between 0.44 ± 0.06 and 2.55 ± 0.35 mSv. ULD-CT protocols provided a mean sensitivity (i.e., correctly detected shunt complications) of 98.2 %. Unnoticed or incorrectly identified complications did not exceed one complication (4.5 %) in any ULD-CT protocol. Diagnostic confidence was sufficient for all ULD-CT protocols except for protocols with 80 kV and 20 mAs.
CONCLUSIONS: ULD-CT allows accurate detection of VP-shunt complications at radiation doses similar or lower than reported for a radiographic shunt series. At the tested radiation dose levels, ULD-CT thus provides an alternative to a radiographic shunt series. KEY POINTS: • Ultralow-dose CT accurately detects Ventriculoperitoneal Shunt complications. • Radiation dosage is similar or lower than reported for a radiographic shunt series. • Ultralow-dose CT potentially shortens the diagnostic process when shunt complications are suspected.

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Year:  2015        PMID: 25693666     DOI: 10.1007/s00330-015-3653-z

Source DB:  PubMed          Journal:  Eur Radiol        ISSN: 0938-7994            Impact factor:   5.315


  15 in total

1.  Risk of cancer from diagnostic X-rays: estimates for the UK and 14 other countries.

Authors:  Amy Berrington de González; Sarah Darby
Journal:  Lancet       Date:  2004-01-31       Impact factor: 79.321

Review 2.  Diagnostic imaging of ventriculoperitoneal shunt malfunctions and complications.

Authors:  C D Goeser; M S McLeary; L W Young
Journal:  Radiographics       Date:  1998 May-Jun       Impact factor: 5.333

3.  Estimated risks of radiation-induced fatal cancer from pediatric CT.

Authors:  D Brenner; C Elliston; E Hall; W Berdon
Journal:  AJR Am J Roentgenol       Date:  2001-02       Impact factor: 3.959

4.  Iterative reconstruction techniques for computed tomography part 2: initial results in dose reduction and image quality.

Authors:  Martin J Willemink; Tim Leiner; Pim A de Jong; Linda M de Heer; Rutger A J Nievelstein; Arnold M R Schilham; Ricardo P J Budde
Journal:  Eur Radiol       Date:  2013-01-16       Impact factor: 5.315

5.  How far can the radiation dose be lowered in head CT with iterative reconstruction? Analysis of imaging quality and diagnostic accuracy.

Authors:  Tung-Hsin Wu; Sheng-Che Hung; Jing-Yi Sun; Chung-Jung Lin; Chung-Hsien Lin; Chen Fen Chiu; Min-Jsuan Liu; Michael Mu Huo Teng; Wan-Yuo Guo; Cheng-Yen Chang
Journal:  Eur Radiol       Date:  2013-05-04       Impact factor: 5.315

6.  Dose reduction in standard head CT: first results from a new scanner using iterative reconstruction and a new detector type in comparison with two previous generations of multi-slice CT.

Authors:  C Ozdoba; J Slotboom; G Schroth; S Ulzheimer; R Kottke; H Watzal; C Weisstanner
Journal:  Clin Neuroradiol       Date:  2014-01-31       Impact factor: 3.649

7.  Detection of ventricular shunt malfunction in the ED: relative utility of radiography, CT, and nuclear imaging.

Authors:  Bruce E Lehnert; Habib Rahbar; Annemarie Relyea-Chew; David H Lewis; Michael L Richardson; James R Fink
Journal:  Emerg Radiol       Date:  2011-04-27

8.  Low-dose protocol for head CT in monitoring hydrocephalus in children.

Authors:  Krzysztof Rybka; Anna Maria Staniszewska; Tadeusz Biegański
Journal:  Med Sci Monit       Date:  2007-05

Review 9.  Cancer risks following diagnostic and therapeutic radiation exposure in children.

Authors:  Ruth A Kleinerman
Journal:  Pediatr Radiol       Date:  2006-09

10.  A low radiation computed tomography protocol for monitoring shunted hydrocephalus.

Authors:  Kuriakose J George; Deb Roy
Journal:  Surg Neurol Int       Date:  2012-09-13
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  1 in total

1.  Development and implementation of an ultralow-dose CT protocol for the assessment of cerebrospinal shunts in adult hydrocephalus.

Authors:  David J Ryan; Richard G Kavanagh; Stella Joyce; Mika O'Callaghan Maher; Niamh Moore; Aisling McMahon; Deirdre Hussey; Michael G J O'Sullivan; Gerald Wyse; Noel Fanning; Owen J O'Connor; Michael M Maher
Journal:  Eur Radiol Exp       Date:  2021-06-28
  1 in total

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