Literature DB >> 2569366

Histamine 2 receptor blocker in the treatment of protamine related anaphylactoid reactions: two case reports.

J R Kambam1, W H Merrill, B E Smith.   

Abstract

Two case reports are described of acute anaphylactoid reactions following the administration of protamine to reverse the anticoagulation effect of heparin in patients undergoing coronary artery bypass graft surgery. The administration of cimetidine seemed to reverse the anaphylactoid reaction after conventional treatment with epinephrine, H1 receptor blocker, and steroids had failed. We recommend that H2 receptor blockade be included with other drugs in the treatment of anaphylactoid reactions following protamine, and possibly after anaphylactoid reactions associated with other substances.

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Year:  1989        PMID： 2569366     DOI： 10.1007/BF03005349

Source DB:  PubMed          Journal:  Can J Anaesth        ISSN： 0832-610X            Impact factor:   5.063


  11 in total

1.  Prospective evaluation of risk of protamine reactions in patients with NPH insulin-dependent diabetes.

Authors:  J H Levy; J R Zaidan; B Faraj
Journal:  Anesth Analg       Date:  1986-07       Impact factor: 5.108

2.  Hemodynamic changes after the administration of protamine.

Authors:  P A Casthely; K Goodman; P N Fyman; L M Abrams; D Aaron
Journal:  Anesth Analg       Date:  1986-01       Impact factor: 5.108

3.  Catastrophic pulmonary vasoconstriction associated with protamine reversal of heparin.

Authors:  E Lowenstein; W E Johnston; D G Lappas; M N D'Ambra; R C Schneider; W M Daggett; C W Akins; D M Philbin
Journal:  Anesthesiology       Date:  1983-11       Impact factor: 7.892

4.  Sperm autoantibodies as a consequence of vasectomy. I. Within 1 year post-operation.

Authors:  H W Hellema; P Rümke
Journal:  Clin Exp Immunol       Date:  1978-01       Impact factor: 4.330

5.  An anaphylactic reaction to protamine in a patient allergic to fish.

Authors:  J T Knape; J L Schuller; P de Haan; A P de Jong; J G Bovill
Journal:  Anesthesiology       Date:  1981-09       Impact factor: 7.892

6.  Severe circulatory shock following protamine (an anaphylactic reaction).

Authors:  S S Moorthy; W Pond; R G Rowland
Journal:  Anesth Analg       Date:  1980-01       Impact factor: 5.108

7.  Protamine induced arterial hypoxaemia: the relationship to hypoxic pulmonary vasoconstriction.

Authors:  Y D Kim; R Michalik; D E Lees; M Jones; S Hanowell; T E Macnamara
Journal:  Can Anaesth Soc J       Date:  1985-01

8.  Depressed cardiovascular function and altered platelet kinetics following protamine sulfate reversal of heparin activity.

Authors:  T W Wakefield; W M Whitehouse; J C Stanley
Journal:  J Vasc Surg       Date:  1984-03       Impact factor: 4.268

9.  Cardiovascular effects of protamine sulfate in man.

Authors:  N Shapira; H V Schaff; J M Piehler; R D White; J C Still; J R Pluth
Journal:  J Thorac Cardiovasc Surg       Date:  1982-10       Impact factor: 5.209

10.  Cardiovascular effects of protamine sulfate in man.

Authors:  T J Conahan; R W Andrews; H MacVaugh
Journal:  Anesth Analg       Date:  1981-01       Impact factor: 5.108
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  5 in total

Review 1.  Anaphylaxis and food allergy.

Authors:  A W Burks; H A Sampson
Journal:  Clin Rev Allergy Immunol       Date:  1999       Impact factor: 8.667

Review 2.  Treatment of acute anaphylaxis.

Authors:  M Fisher
Journal:  BMJ       Date:  1995-09-16

Review 3.  Anaphylactic shock: mechanisms and treatment.

Authors:  A F Brown
Journal:  J Accid Emerg Med       Date:  1995-06

Review 4.  Critical care pharmacotherapy. A review.

Authors:  M Tryba; P J Kulka
Journal:  Drugs       Date:  1993-03       Impact factor: 9.546

5.  An anaphylactic reaction to protamine sulfate.

Authors:  J A Roelofse; P van der Bijl
Journal:  Anesth Prog       Date:  1991 May-Jun
  5 in total

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