Literature DB >> 25683044

Is immediate reconstruction of the mandible with nonvascularized bone graft following resection of benign pathology a viable treatment option?

Thomas Schlieve1, William Hull2, Michael Miloro3, Antonia Kolokythas4.   

Abstract

PURPOSE: The purpose of this study was to address the following clinical question: Is immediate reconstruction of the mandible with a nonvascularized bone graft after resection of benign pathology a viable treatment option? Another purpose was to determine whether any variables affect the success of this treatment approach.
MATERIALS AND METHODS: The authors implemented a retrospective cohort study from a sample of patients diagnosed with a benign tumor of the mandible who were treated with segmental resection and primary reconstruction with an autogenous nonvascularized bone graft. The predictor variables were age, gender, lesion size, and diagnosis, and the outcome variable was graft success determined by re-establishment of mandibular continuity with sufficient bone for implant placement. The χ(2) test was used for statistical analysis of the categorical data and P values less than .05 were considered statistically significant.
RESULTS: Twenty patients with benign mandibular tumors were treated with transoral resection and immediate reconstruction with nonvascularized bone grafts. The mean age was 28.3 years (range, 9 to 63 yr) and 55% (11 of 20) were men. The most common lesion type was ameloblastoma (13 of 20) and all patients underwent reconstruction with autogenous anterior iliac crest bone grafting. Ninety percent of patients (18 of 20) had successful reconstruction. Ten patients underwent successful implant placement and restoration.
CONCLUSIONS: Using careful patient selection, treatment of benign pathology with transoral resection and immediate reconstruction with a nonvascularized bone graft from the anterior iliac crest can be successful. In addition, the total treatment time from implant restoration to return to preoperative function is minimized. Therefore, this method of treatment is a viable treatment option and an alternative to delayed reconstruction or reconstruction with vascularized bone flaps.
Copyright © 2015 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

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Year:  2014        PMID: 25683044     DOI: 10.1016/j.joms.2014.10.019

Source DB:  PubMed          Journal:  J Oral Maxillofac Surg        ISSN: 0278-2391            Impact factor:   1.895


  8 in total

1.  Nonvascularized Bone Graft Reconstruction of the Irradiated Murine Mandible: An Analogue of Clinical Head and Neck Cancer Treatment.

Authors:  Kevin M Urlaub; Russell E Ettinger; Noah S Nelson; Jessie M Hoxie; Alicia E Snider; Joseph E Perosky; Yekaterina Polyatskaya; Alexis Donneys; Steven R Buchman
Journal:  J Craniofac Surg       Date:  2019 Mar/Apr       Impact factor: 1.046

2.  Reconstruction of tooth-bearing portion of mandible using polyglactin 910 sutures for internal fixation in the third-world: functional and cosmetic outcome.

Authors:  Bayo Aluko-Olokun; Ademola A Olaitan; Oluseun A Aluko-Olokun
Journal:  Oral Maxillofac Surg       Date:  2016-10-29

3.  Non-vascularised iliac crest bone graft for immediate reconstruction of lateral mandibular defect.

Authors:  Eyituoyo Okoturo
Journal:  Oral Maxillofac Surg       Date:  2016-10-10

4.  Immediate reconstruction of segmental mandibular defects via tissue engineering.

Authors:  Robert O Weiss; Patrick E Wong; Likith V Reddy
Journal:  Proc (Bayl Univ Med Cent)       Date:  2022-03-03

5.  Mandibular Reconstruction With Block Iliac Crest: An Institutional Experience.

Authors:  Camila Camarini; Guilherme Spagnol; Manuela Monteiro Pinotti; Alan Motta do Canto; Fernando Alves Maciel; Ronaldo Rodrigues de Freitas
Journal:  Craniomaxillofac Trauma Reconstr       Date:  2020-08-17

6.  Costal Grafting in Mandibular Reconstruction.

Authors:  Jean-Thomas Bachelet; Jerôme Bourlet; Joseph Château; Mathieu Jacquemart; Clémence Dufour; Ali Mojallal; Arnaud Gleizal
Journal:  Plast Reconstr Surg Glob Open       Date:  2015-12-09

7.  Mandibular reconstruction with autogenous non-vascularised bone graft.

Authors:  Ramat Oyebunmi Braimah; Adebayo Aremu Ibikunle; Umar Abubakar; Abdurrazaq Olanrewaju Taiwo; Muhammed Oboirien; Francis Adewale Adejobi; Terry Godwin Ndubuisi; Siddiq Abubakar
Journal:  Afr Health Sci       Date:  2019-09       Impact factor: 0.927

8.  A retrospective study on mandibular reconstruction using iliac crest free flap.

Authors:  Ata Garajei; Ali A Kheradmand; Seyed Roohollah Miri; Azadeh Emami
Journal:  Ann Med Surg (Lond)       Date:  2021-05-05
  8 in total

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