BACKGROUND: A 26-year-old female with myasthenic crisis developed transfusion-related acute lung injury (TRALI) after she was treated with intravenous immunoglobulin. METHODS: Case report. RESULTS: Respiratory status markedly worsened with each intravenous immunoglobulin (IVIG) administration and progressing from a need to use bilevel positive airway pressure (BiPAP) to intubation. Pulmonary function tests improved during this episode. CONCLUSIONS: IVIG may cause TRALI and due to subtle clinical findings can be mistaken for neuromuscular respiratory failure.
BACKGROUND: A 26-year-old female with myasthenic crisis developed transfusion-related acute lung injury (TRALI) after she was treated with intravenous immunoglobulin. METHODS: Case report. RESULTS: Respiratory status markedly worsened with each intravenous immunoglobulin (IVIG) administration and progressing from a need to use bilevel positive airway pressure (BiPAP) to intubation. Pulmonary function tests improved during this episode. CONCLUSIONS: IVIG may cause TRALI and due to subtle clinical findings can be mistaken for neuromuscular respiratory failure.
Authors: Francesco Santoro; Elena Carapelle; Sofia Isabel Cieza Ortiz; Francesco Musaico; Armando Ferraretti; Giuseppe d'Orsi; Luigi Maria Specchio; Matteo Di Biase; Natale Daniele Brunetti Journal: Int J Cardiol Date: 2013-04-19 Impact factor: 4.164
Authors: A Stoclin; F Delbos; G Dauriat; O Brugière; N Boeri; A C Métivier; G Thabut; P Camus; H Mal Journal: Vox Sang Date: 2012-09-18 Impact factor: 2.144
Authors: José Roberto Mendes Pegler; Ana Paula Beltran Moschione Castro; Antonio Carlos Pastorino; Mayra de Barros Dorna Journal: Einstein (Sao Paulo) Date: 2020-12-07