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Literature DB >> 25677705

Fecal microbiota transplantation for the management of Clostridium difficile infection.

Abstract

This article discusses the use of fecal microbiota transplantation (FMT) for the treatment of recurrent Clostridium difficile infection (CDI). The disruption of the normal gut microbiota is central to the pathogenesis of CDI, and disruption persists in recurrent disease. The use of FMT for recurrent CDI is characterized by a high response rate and short term safety is excellent, although the long-term effects of FMT are as yet unknown.

Entities: Chemical Disease Gene Species

Keywords: Clostridium difficile; Colitis; Fecal microbiota transplantation; Microbiome; Nonantibiotic treatment; Recurrent C difficile infection

Mesh：

Year: 2015 PMID： 25677705 PMCID： PMC4328137 DOI： 10.1016/j.idc.2014.11.009

Source DB: PubMed Journal: Infect Dis Clin North Am ISSN： 0891-5520 Impact factor: 5.982

61 in total

1. Treatment of recurrent Clostridium difficile-associated diarrhea by administration of donated stool directly through a colonoscope.

Authors: S E Persky; L J Brandt
Journal: Am J Gastroenterol Date: 2000-11 Impact factor: 10.864

2. Fecal enema as an adjunct in the treatment of pseudomembranous enterocolitis.

Authors: B EISEMAN; W SILEN; G S BASCOM; A J KAUVAR
Journal: Surgery Date: 1958-11 Impact factor: 3.982

3. Decreased diversity of the fecal Microbiome in recurrent Clostridium difficile-associated diarrhea.

Authors: Ju Young Chang; Dionysios A Antonopoulos; Apoorv Kalra; Adriano Tonelli; Walid T Khalife; Thomas M Schmidt; Vincent B Young
Journal: J Infect Dis Date: 2008-02-01 Impact factor: 5.226

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Journal: Lancet Date: 2001-01-20 Impact factor: 79.321

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Authors: L Clifford McDonald; Bruno Coignard; Erik Dubberke; Xiaoyan Song; Teresa Horan; Preeta K Kutty
Journal: Infect Control Hosp Epidemiol Date: 2007-01-25 Impact factor: 3.254

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Journal: Clin Infect Dis Date: 2003-02-14 Impact factor: 9.079

7. Asymptomatic carriers are a potential source for transmission of epidemic and nonepidemic Clostridium difficile strains among long-term care facility residents.

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Journal: Clin Infect Dis Date: 2007-09-04 Impact factor: 9.079

8. Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial.

Authors: Marc Gh Besselink; Hjalmar C van Santvoort; Erik Buskens; Marja A Boermeester; Harry van Goor; Harro M Timmerman; Vincent B Nieuwenhuijs; Thomas L Bollen; Bert van Ramshorst; Ben Jm Witteman; Camiel Rosman; Rutger J Ploeg; Menno A Brink; Alexander Fm Schaapherder; Cornelis Hc Dejong; Peter J Wahab; Cees Jhm van Laarhoven; Erwin van der Harst; Casper Hj van Eijck; Miguel A Cuesta; Louis Ma Akkermans; Hein G Gooszen
Journal: Lancet Date: 2008-02-14 Impact factor: 79.321

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Journal: Am J Gastroenterol Date: 2002-07 Impact factor: 10.864

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Authors: Thomas J Borody; Eloise F Warren; Sharyn M Leis; Rosa Surace; Ori Ashman; Steven Siarakas
Journal: J Clin Gastroenterol Date: 2004-07 Impact factor: 3.062

24 in total

Review 1. Recurrent Clostridium difficile infection and the microbiome.

Authors: Rowena Almeida; Teklu Gerbaba; Elaine O Petrof
Journal: J Gastroenterol Date: 2015-07-08 Impact factor: 7.527

Review 2. Probiotics for prevention of Clostridium difficile infection.

Authors: John P Mills; Krishna Rao; Vincent B Young
Journal: Curr Opin Gastroenterol Date: 2018-01 Impact factor: 3.287

3. Capsules for Fecal Microbiota Transplantation in Recurrent Clostridium difficile Infection: The New Way Forward or a Tough Pill to Swallow?

Authors: Krishna Rao; Vincent B Young; Preeti N Malani
Journal: JAMA Date: 2017-11-28 Impact factor: 56.272

4. Use of a neutralizing antibody helps identify structural features critical for binding of Clostridium difficile toxin TcdA to the host cell surface.

Authors: Heather K Kroh; Ramyavardhanee Chandrasekaran; Kim Rosenthal; Rob Woods; Xiaofang Jin; Melanie D Ohi; Andrew C Nyborg; G Jonah Rainey; Paul Warrener; Benjamin W Spiller; D Borden Lacy
Journal: J Biol Chem Date: 2017-07-13 Impact factor: 5.157

Review 5. Clinical Practice and Infrastructure Review of Fecal Microbiota Transplantation for Clostridium difficile Infection.

Authors: Brendan J Kelly; Pablo Tebas
Journal: Chest Date: 2017-09-18 Impact factor: 9.410

6. Fecal Microbiota Transplantation Eliminates Clostridium difficile in a Murine Model of Relapsing Disease.

Authors: Anna M Seekatz; Casey M Theriot; Caitlyn T Molloy; Katherine L Wozniak; Ingrid L Bergin; Vincent B Young
Journal: Infect Immun Date: 2015-07-13 Impact factor: 3.441

Review 7. Microbial therapeutic interventions.

Authors: Nicole G Grady; Elaine O Petrof; Erika C Claud
Journal: Semin Fetal Neonatal Med Date: 2016-04-25 Impact factor: 3.926