| Literature DB >> 25677521 |
Thomas Thum1, Gianluigi Condorelli2.
Abstract
RNAs not encoding proteins have gained prominence over the last couple of decades as fundamental regulators of cellular function. Not surprisingly, their dysregulation is increasingly being linked to pathology. Here, we review recent reports investigating the pathophysiological relevance of this species of RNA for the cardiovascular system, concentrating mainly on recent findings on long noncoding RNAs and microRNAs in cardiac hypertrophy and failure.Entities:
Keywords: cardiac hypertrophy; cardiac remodelling; heart failure; lncRNAs; microRNAs; myocardial infarction
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Year: 2015 PMID: 25677521 DOI: 10.1161/CIRCRESAHA.116.303549
Source DB: PubMed Journal: Circ Res ISSN: 0009-7330 Impact factor: 17.367