Literature DB >> 25677521

Long noncoding RNAs and microRNAs in cardiovascular pathophysiology.

Thomas Thum1, Gianluigi Condorelli2.   

Abstract

RNAs not encoding proteins have gained prominence over the last couple of decades as fundamental regulators of cellular function. Not surprisingly, their dysregulation is increasingly being linked to pathology. Here, we review recent reports investigating the pathophysiological relevance of this species of RNA for the cardiovascular system, concentrating mainly on recent findings on long noncoding RNAs and microRNAs in cardiac hypertrophy and failure.
© 2015 American Heart Association, Inc.

Entities:  

Keywords:  cardiac hypertrophy; cardiac remodelling; heart failure; lncRNAs; microRNAs; myocardial infarction

Mesh:

Substances:

Year:  2015        PMID: 25677521     DOI: 10.1161/CIRCRESAHA.116.303549

Source DB:  PubMed          Journal:  Circ Res        ISSN: 0009-7330            Impact factor:   17.367


  153 in total

1.  Linc-POU3F3 promotes cell proliferation in gastric cancer via increasing T-reg distribution.

Authors:  Guanying Xiong; Lihua Yang; Yun Chen; Zhining Fan
Journal:  Am J Transl Res       Date:  2015-11-15       Impact factor: 4.060

2.  Harnessing fetal and adult genetic reprograming for therapy of heart disease.

Authors:  Shyam Sundar Nandi; Paras Kumar Mishra
Journal:  J Nat Sci       Date:  2015-04

Review 3.  Inhibition of hypertrophy is a good therapeutic strategy in ventricular pressure overload.

Authors:  Gabriele G Schiattarella; Joseph A Hill
Journal:  Circulation       Date:  2015-04-21       Impact factor: 29.690

4.  Blood Leukocyte DNA Methylation Predicts Risk of Future Myocardial Infarction and Coronary Heart Disease.

Authors:  Golareh Agha; Michael M Mendelson; Cavin K Ward-Caviness; Roby Joehanes; TianXiao Huan; Rahul Gondalia; Elias Salfati; Jennifer A Brody; Giovanni Fiorito; Jan Bressler; Brian H Chen; Symen Ligthart; Simonetta Guarrera; Elena Colicino; Allan C Just; Simone Wahl; Christian Gieger; Amy R Vandiver; Toshiko Tanaka; Dena G Hernandez; Luke C Pilling; Andrew B Singleton; Carlotta Sacerdote; Vittorio Krogh; Salvatore Panico; Rosario Tumino; Yun Li; Guosheng Zhang; James D Stewart; James S Floyd; Kerri L Wiggins; Jerome I Rotter; Michael Multhaup; Kelly Bakulski; Steven Horvath; Philip S Tsao; Devin M Absher; Pantel Vokonas; Joel Hirschhorn; M Daniele Fallin; Chunyu Liu; Stefania Bandinelli; Eric Boerwinkle; Abbas Dehghan; Joel D Schwartz; Bruce M Psaty; Andrew P Feinberg; Lifang Hou; Luigi Ferrucci; Nona Sotoodehnia; Giuseppe Matullo; Annette Peters; Myriam Fornage; Themistocles L Assimes; Eric A Whitsel; Daniel Levy; Andrea A Baccarelli
Journal:  Circulation       Date:  2019-08-19       Impact factor: 29.690

5.  My heart will go on-beneficial effects of anti-MiR-30 after myocardial infarction.

Authors:  Yuhuang Li; Lars Maegdefessel
Journal:  Ann Transl Med       Date:  2016-04

Review 6.  Epigenetic modifications and noncoding RNAs in cardiac hypertrophy and failure.

Authors:  Carolina M Greco; Gianluigi Condorelli
Journal:  Nat Rev Cardiol       Date:  2015-05-12       Impact factor: 32.419

Review 7.  Circular RNAs: A Novel Class of Functional RNA Molecules with a Therapeutic Perspective.

Authors:  Laura Santer; Christian Bär; Thomas Thum
Journal:  Mol Ther       Date:  2019-07-09       Impact factor: 11.454

8.  MicroRNA and hyperglycemic memory in the diabetic heart.

Authors:  Shinji Ogawa; Yasuhide Okawa; Koshi Sawada; Yoshihiro Goto; Soh Hosoba; Syunsuke Fukaya
Journal:  J Thorac Dis       Date:  2016-11       Impact factor: 2.895

9.  HOTAIR functions as a competing endogenous RNA to regulate PTEN expression by inhibiting miR-19 in cardiac hypertrophy.

Authors:  Yanjun Lai; Shuai He; Liming Ma; Hong Lin; Biyun Ren; Jing Ma; Xinyu Zhu; Shifang Zhuang
Journal:  Mol Cell Biochem       Date:  2017-03-18       Impact factor: 3.396

Review 10.  Non-coding RNAs in cardiovascular diseases: diagnostic and therapeutic perspectives.

Authors:  Wolfgang Poller; Stefanie Dimmeler; Stephane Heymans; Tanja Zeller; Jan Haas; Mahir Karakas; David-Manuel Leistner; Philipp Jakob; Shinichi Nakagawa; Stefan Blankenberg; Stefan Engelhardt; Thomas Thum; Christian Weber; Benjamin Meder; Roger Hajjar; Ulf Landmesser
Journal:  Eur Heart J       Date:  2018-08-01       Impact factor: 29.983

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