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Literature DB >> 2567700

Chromosomal localization of the human homeo box-containing genes, EN1 and EN2.

C Logan¹, H F Willard, J M Rommens, A L Joyner.

Abstract

The human homologs of the mouse homeo box-containing genes, En-1 and En-2, which show homology to the Drosophila engrailed gene, have been isolated. The human EN1 gene was mapped to chromosome 2 by analysis of mouse-human somatic cell hybrids. The human EN2 gene was localized to chromosome 7, 7q32-7qter, by analysis of rodent-human somatic cell hybrids and cell lines carrying portions of chromosome 7.

Entities: Gene Species

Mesh：

Year: 1989 PMID： 2567700 DOI： 10.1016/0888-7543(89)90301-7

Source DB: PubMed Journal: Genomics ISSN： 0888-7543 Impact factor: 5.736

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Cited

11 in total

Review 1. Preservation of duplicate genes by complementary, degenerative mutations.

Authors: A Force; M Lynch; F B Pickett; A Amores; Y L Yan; J Postlethwait
Journal: Genetics Date: 1999-04 Impact factor: 4.562

Review 2. Comparative map for mice and humans.

Authors: J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M R Kosowsky; T H Roderick
Journal: Mamm Genome Date: 1992 Impact factor: 2.957

3. Molecular characterization and silk gland expression of Bombyx engrailed and invected genes.

Authors: C C Hui; K Matsuno; K Ueno; Y Suzuki
Journal: Proc Natl Acad Sci U S A Date: 1992-01-01 Impact factor: 11.205

Review 4. Comparative map for mice and humans.

Authors: J H Nadeau; M T Davisson; D P Doolittle; P Grant; A L Hillyard; M Kosowsky; T H Roderick
Journal: Mamm Genome Date: 1991 Impact factor: 2.957

10. Assignment of the locus for Waardenburg syndrome type I to human chromosome 2q37 and possible homology to the Splotch mouse.

Authors: C Foy; V Newton; D Wellesley; R Harris; A P Read
Journal: Am J Hum Genet Date: 1990-06 Impact factor: 11.025

Chromosomal localization of the human homeo box-containing genes, EN1 and EN2.

Review 1. Preservation of duplicate genes by complementary, degenerative mutations.

Review 2. Comparative map for mice and humans.

3. Molecular characterization and silk gland expression of Bombyx engrailed and invected genes.

Review 4. Comparative map for mice and humans.

5. Localization of the reeler gene relative to flanking loci on mouse chromosome 5.

6. Fate of midbrain dopaminergic neurons controlled by the engrailed genes.

7. Localization of the inhibin beta B gene on mouse chromosome 1.

8. Involvement of the EN-2 gene in normal and abnormal development of the human arcuate nucleus.

9. Molecular cytogenetic analysis of patients with holoprosencephaly and structural rearrangements of 7q.

10. Assignment of the locus for Waardenburg syndrome type I to human chromosome 2q37 and possible homology to the Splotch mouse.