Literature DB >> 25676131

A rare case of Waterhouse-Friderichsen syndrome caused by Capnocytophaga canimorsus in an immunocompetent patient.

Joseph David Cooper1, Robert Patrick Dorion2, Joseph Lorenzo Smith3.   

Abstract

A 53-year-old Caucasian male with hypertension and active tobacco abuse presented to a community hospital with a 2-day history of vague abdominal pain, myalgia and increased lethargy after being bitten on his right hand by the family dog while camping just 3 days prior to symptom onset. He expired within 90 min upon arrival to our intensive care unit. Pre-mortem blood cultures grew a fastidious Gram-negative aerobic rod that was identified as Capnocytophaga canimorsus. Autopsy findings showed multi-organ disseminated intravascular coagulopathy with microthrombi along with bilateral adrenal hemorrhage and necrosis of the adrenal glands consistent with Waterhouse-Friderichsen syndrome. This case contributes to the medical literature as a rare presentation of Capnocytophaga canimorsus infection in an otherwise immunocompetent patient and stresses the importance of a thorough history taking and physical examination by clinicians along with prompt administration of appropriate antibiotics.

Entities:  

Keywords:  Capnocytophaga canimorsus; Dog bite; Waterhouse-Friderichsen syndrome

Mesh:

Year:  2015        PMID: 25676131     DOI: 10.1007/s15010-015-0740-7

Source DB:  PubMed          Journal:  Infection        ISSN: 0300-8126            Impact factor:   3.553


  12 in total

1.  Waterhouse-Friderichsen syndrome secondary to Capnocytophaga canimorsus septicemia and demonstration of bacteremia by peripheral blood smear.

Authors:  I Mirza; J Wolk; L Toth; P Rostenberg; R Kranwinkel; S C Sieber
Journal:  Arch Pathol Lab Med       Date:  2000-06       Impact factor: 5.534

2.  A series of infections due to Capnocytophaga spp in immunosuppressed and immunocompetent patients.

Authors:  H Bonatti; D W Rossboth; D Nachbaur; M Fille; C Aspöck; I Hend; K Hourmont; L White; H Malnick; F J Allerberger
Journal:  Clin Microbiol Infect       Date:  2003-05       Impact factor: 8.067

3.  Acute onset of fever, chills, and lethargy in a 36-year-old woman.

Authors:  Madalina Minciu Macrea; Michael McNamee; Thomas J Martin
Journal:  Chest       Date:  2008-06       Impact factor: 9.410

4.  Susceptibility of dysgonic fermenter 2 to antimicrobial agents in vitro.

Authors:  A Verghese; F Hamati; S Berk; B Franzus; S Berk; J K Smith
Journal:  Antimicrob Agents Chemother       Date:  1988-01       Impact factor: 5.191

5.  Capnocytophaga canimorsus sp. nov. (formerly CDC group DF-2), a cause of septicemia following dog bite, and C. cynodegmi sp. nov., a cause of localized wound infection following dog bite.

Authors:  D J Brenner; D G Hollis; G R Fanning; R E Weaver
Journal:  J Clin Microbiol       Date:  1989-02       Impact factor: 5.948

6.  Fatal dog bite in the absence of significant trauma: Capnocytophaga canimorsus infection and unexpected death.

Authors:  Denise Stiegler; John D Gilbert; Morgyn S Warner; Roger W Byard
Journal:  Am J Forensic Med Pathol       Date:  2010-06       Impact factor: 0.921

7.  "Beware man's best friend".

Authors:  Caroline Cleuziou; Aymeric Binard; Valérie Devauchelle-Pensec; Genevieve Héry-Arnaud; Sandrine Jousse-Joulin; Alain Saraux
Journal:  Spine (Phila Pa 1976)       Date:  2010-12-01       Impact factor: 3.468

8.  Intracellular multiplication and toxic destruction of cultured macrophages by Capnocytophaga canimorsus.

Authors:  L J Fischer; R S Weyant; E H White; F D Quinn
Journal:  Infect Immun       Date:  1995-09       Impact factor: 3.441

9.  Waterhouse-Friderichsen syndrome caused by a DF-2 bacterium in a splenectomised patient.

Authors:  A K Chaudhuri; R B Hartley; A C Maddocks
Journal:  J Clin Pathol       Date:  1981-02       Impact factor: 3.411

10.  Resistance of Capnocytophaga canimorsus to killing by human complement and polymorphonuclear leukocytes.

Authors:  Hwain Shin; Manuela Mally; Salome Meyer; Chantal Fiechter; Cécile Paroz; Ulrich Zaehringer; Guy R Cornelis
Journal:  Infect Immun       Date:  2009-03-23       Impact factor: 3.441

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  8 in total

1.  Urticarial exanthem associated with Capnocytophaga canimorsus bacteremia after a dog bite.

Authors:  Christian S Jordan; Una Miniter; Kevin Yarbrough; Stephanie J Mengden
Journal:  JAAD Case Rep       Date:  2016-03-03

2.  Capnocytophaga canimorsus sepsis in a methotrexate-treated patient with rheumatoid arthritis.

Authors:  Shinobu Tamura; Asumi Koyama; Yusuke Yamashita; Chieko Shiotani; Hiromichi Nakamoto; Chiaki Nakamoto; Michio Suzuki; Yoshio Nakano; Koichi Imaoka; Takashi Sonoki; Tokuzo Fujimoto
Journal:  IDCases       Date:  2017-08-05

3.  A unique fatal case of Waterhouse-Friderichsen syndrome caused by Proteus mirabilis in an immunocompetent subject: Case report and literature analysis.

Authors:  Elvira Ventura Spagnolo; Cristina Mondello; Salvatore Roccuzzo; Chiara Stassi; Luigi Cardia; Angela Grieco; Cataldo Raffino
Journal:  Medicine (Baltimore)       Date:  2019-08       Impact factor: 1.817

4.  Capnocytophaga canimorsus infection led to progressively fatal septic shock in an immunocompetent patient.

Authors:  Ryuichi Nakayama; Shuichi Miyamoto; Toshihiro Tawara; Arisa Aoyagi; Takeo Oguro; Nobumichi Kobayashi; Michio Suzuki; Yoshihiro Takeyama
Journal:  Acute Med Surg       Date:  2022-02-19

5.  [Sepsis caused by Capnocytophaga canimorsus in an immunocompetent patient].

Authors:  D Fernández Vecilla; F E Calvo Muro; F Renzi; J L Díaz de Tuesta Del Arco
Journal:  Rev Esp Quimioter       Date:  2022-04-26       Impact factor: 2.515

6.  Lethal Waterhouse-Friderichsen syndrome caused by Capnocytophaga canimorsus in an asplenic patient.

Authors:  Franziska Schuler; Jan-Sören Padberg; Carsten Hullermann; Philipp Kümpers; Johannes Lepper; Miriam Schulte; Andreas Uekötter; Frieder Schaumburg; Barbara C Kahl
Journal:  BMC Infect Dis       Date:  2022-08-17       Impact factor: 3.667

7.  A case of septic arthritis caused by Capnocytophaga canimorsus in an HIV patient.

Authors:  Domingo Fernández Vecilla; Cristina Aspichueta Vivanco; Itziar Angulo López; Josu Mirena Baraia-Etxaburu Artetxe; Francesco Renzi; José Luis Díaz de Tuesta Del Arco
Journal:  Access Microbiol       Date:  2022-06-15

8.  Purpura Fulminans and Septic Shock due to Capnocytophaga Canimorsus after Dog Bite: A Case Report and Review of the Literature.

Authors:  Elena Mantovani; Stefano Busani; Emanuela Biagioni; Claudia Venturelli; Lucia Serio; Massimo Girardis
Journal:  Case Rep Crit Care       Date:  2018-08-26
  8 in total

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