Literature DB >> 25675136

Health-promoting effects of the citrus flavanone hesperidin.

Chaoyun Li1, Hermann Schluesener1.   

Abstract

Hesperidin, a member of the flavanone group of flavonoids, can be isolated in large amounts from the rinds of some citrus species. Considering the wide range of pharmacological activities and widespread application of hesperidin, this paper reviews preclinical and clinical trials of hesperidin and its related compounds, including their occurrence, pharmacokinetics, and some marketed products available. Preclinical studies and clinical trials demonstrated therapeutical effects of hesperidin and its aglycone hesperetin in various diseases, such as neurological disorders, psychiatric disorders, and cardiovascular diseases and others, due to its anti-inflammatory, antioxidant, lipid-lowering, and insulin-sensitizing properties.

Entities:  

Keywords:  Hesperidin; hesperitin; pharmacokinetics; pharmacology

Mesh：

Substances：

Year:  2017        PMID： 25675136     DOI： 10.1080/10408398.2014.906382

Source DB:  PubMed          Journal:  Crit Rev Food Sci Nutr        ISSN： 1040-8398            Impact factor:   11.176


  50 in total

Review 1.  Molecular mechanisms of action of hesperidin in cancer: Recent trends and advancements.

Authors:  Vaishali Aggarwal; Hardeep S Tuli; Falak Thakral; Paavan Singhal; Diwakar Aggarwal; Saumya Srivastava; Anjana Pandey; Katrin Sak; Mehmet Varol; Md Asaduzzaman Khan; Gautam Sethi
Journal:  Exp Biol Med (Maywood)       Date:  2020-02-12

2.  Hesperidin Preserves Cognitive Functions and Hippocampus Histological Architecture in Albino Wistar Rats Subjected to Stress Through Enhancement of Brain-Derived Neurotrophic Factor.

Authors:  Ahmed S Ahmed; Marwa M Mona; Rasha A Elsisy; Ehab M Hantash
Journal:  Neurotox Res       Date:  2021-11-26       Impact factor: 3.911

3.  Hesperetin, a Citrus Flavonoid, Ameliorates Inflammatory Cytokine-Mediated Inhibition of Oligodendroglial Cell Morphological Differentiation.

Authors:  Satoshi Nishino; Yoko Fujiki; Takanari Sato; Yukino Kato; Remina Shirai; Hiroaki Oizumi; Masahiro Yamamoto; Katsuya Ohbuchi; Yuki Miyamoto; Kazushige Mizoguchi; Junji Yamauchi
Journal:  Neurol Int       Date:  2022-05-31

Review 4.  Therapeutic Effects of Citrus Flavonoids Neohesperidin, Hesperidin and Its Aglycone, Hesperetin on Bone Health.

Authors:  Adriana de Cássia Ortiz; Simone Ortiz Moura Fideles; Carlos Henrique Bertoni Reis; Márcia Zilioli Bellini; Eliana de Souza Bastos Mazuqueli Pereira; João Paulo Galletti Pilon; Miguel Ângelo de Marchi; Cláudia Rucco Penteado Detregiachi; Uri Adrian Prync Flato; Beatriz Flavia de Moraes Trazzi; Bruna Trazzi Pagani; José Burgos Ponce; Taiane Priscila Gardizani; Fulvia de Souza Veronez; Daniela Vieira Buchaim; Rogerio Leone Buchaim
Journal:  Biomolecules       Date:  2022-04-23

5.  Hesperidin Bioavailability Is Increased by the Presence of 2S-Diastereoisomer and Micronization-A Randomized, Crossover and Double-Blind Clinical Trial.

Authors:  Anna Crescenti; Antoni Caimari; Juan María Alcaide-Hidalgo; Roger Mariné-Casadó; Rosa M Valls; Judit Companys; Patricia Salamanca; Lorena Calderón-Pérez; Laura Pla-Pagà; Anna Pedret; Antoni Delpino-Rius; Pol Herrero; Iris Samarra; Lluís Arola; Rosa Solà; Josep M Del Bas
Journal:  Nutrients       Date:  2022-06-15       Impact factor: 6.706

Review 6.  Hesperidin: A Review on Extraction Methods, Stability and Biological Activities.

Authors:  Krystyna Pyrzynska
Journal:  Nutrients       Date:  2022-06-09       Impact factor: 6.706

7.  Flaxseed and/or hesperidin supplementation in metabolic syndrome: an open-labeled randomized controlled trial.

Authors:  Zahra Yari; Makan Cheraghpour; Azita Hekmatdoost
Journal:  Eur J Nutr       Date:  2020-04-15       Impact factor: 5.614

8.  Protective Effects of Hesperidin (Citrus Flavonone) on High Glucose Induced Oxidative Stress and Apoptosis in a Cellular Model for Diabetic Retinopathy.

Authors:  Wayne Young Liu; Shorong-Shii Liou; Tang-Yao Hong; I-Min Liu
Journal:  Nutrients       Date:  2017-12-02       Impact factor: 5.717

Review 9.  Natural Compounds: A Potential Treatment for Alcoholic Liver Disease?

Authors:  Junbin Yan; Yunmeng Nie; Minmin Luo; Zhiyun Chen; Beihui He
Journal:  Front Pharmacol       Date:  2021-07-05       Impact factor: 5.810

Review 10.  Flavonoids on diabetic nephropathy: advances and therapeutic opportunities.

Authors:  Qichao Hu; Caiyan Qu; Xiaolin Xiao; Wenwen Zhang; Yinxiao Jiang; Zhao Wu; Dan Song; Xi Peng; Xiao Ma; YanLing Zhao
Journal:  Chin Med       Date:  2021-08-07       Impact factor: 5.455
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.