Gâlea Carmen1, Gabriel Hancu2. 1. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University "Lucian Blaga", Sibiu, Romania. 2. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Medicine and Pharmacy, Târgu Mureş, Romania.
Abstract
PURPOSE: The antiseptic qualities of aromatic and medicinal plants and their extracts have been recognized since antiquity, while attempts to characterize these properties in the laboratory date back the beginning of the XX(th) century. In the current study essential oils obtained from Pelargonium roseum (Geraniacea) were analyzed for their antibacterial and antifungal activities. METHODS: The antimicrobial activity of the Pelargonium essential oil was tested against Gram-negative bacteria (Pseudomonas aeruginosa, Proteus mirabilis, Escherichia coli), Gram-positive bacteria (Staphylococcus aureus, Enterococcus faecalis) and fungi (Candida albicans). Disc diffusion method was used to study antimicrobial activity. RESULTS: Inhibition zones showed that the studied essential oils were active against all of the studied bacteria. In the case of Candida albicans, the complete inhibition of the fungus's development was observed. In the cases of Pseudomonas aeruginosa and Staphylococcus aureus we observed an inhibition comparable to that obtained by the use of an appropriate antimicrobial substance. CONCLUSION: The volatile oils exhibited considerable inhibitory effects against all the organisms under test, in some cases comparable with those of the reference antibiotics. There were no considerable differences between the antimicrobial activities of the oil obtained by distillation and commercially available Pelargonium oils.
PURPOSE: The antiseptic qualities of aromatic and medicinal plants and their extracts have been recognized since antiquity, while attempts to characterize these properties in the laboratory date back the beginning of the XX(th) century. In the current study essential oils obtained from Pelargonium roseum (Geraniacea) were analyzed for their antibacterial and antifungal activities. METHODS: The antimicrobial activity of the Pelargonium essential oil was tested against Gram-negative bacteria (Pseudomonas aeruginosa, Proteus mirabilis, Escherichia coli), Gram-positive bacteria (Staphylococcus aureus, Enterococcus faecalis) and fungi (Candida albicans). Disc diffusion method was used to study antimicrobial activity. RESULTS: Inhibition zones showed that the studied essential oils were active against all of the studied bacteria. In the case of Candida albicans, the complete inhibition of the fungus's development was observed. In the cases of Pseudomonas aeruginosa and Staphylococcus aureus we observed an inhibition comparable to that obtained by the use of an appropriate antimicrobial substance. CONCLUSION: The volatile oils exhibited considerable inhibitory effects against all the organisms under test, in some cases comparable with those of the reference antibiotics. There were no considerable differences between the antimicrobial activities of the oil obtained by distillation and commercially available Pelargonium oils.
Authors: Samantha Coronado-López; Stefany Caballero-García; Miguel Angel Aguilar-Luis; Fernando Mazulis; Juana Del Valle-Mendoza Journal: Int J Dent Date: 2018-11-28