Bianca Maceo Heilman1, Fabrice Manns1, Alberto de Castro2, Heather Durkee1, Esdras Arrieta3, Susana Marcos2, Jean-Marie Parel4. 1. Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, Miami, Florida, United States Biomedical Optics and Laser Laboratory, Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, Florida, United States. 2. Instituto de Óptica, Consejo Superior de Investigaciones Científicas, Madrid, Spain. 3. Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, Miami, Florida, United States. 4. Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, Miami, Florida, United States Biomedical Optics and Laser Laboratory, Department of Biomedical Engineering, University of Miami College of Engineering, Coral Gables, Florida, United States Vision Cooperative Research Centre, Brien Holden Vision Institute, University of New South Wales, Sydney, New South Wales, Australia.
Abstract
PURPOSE: The purpose of this study was to quantify accommodation-induced changes in the spherical aberration of cynomolgus monkey lenses. METHODS: Twenty-four lenses from 20 cynomolgus monkeys (Macaca fascicularis; 4.4-16.0 years of age; postmortem time 13.5 ± 13.0 hours) were mounted in a lens stretcher. Lens spherical aberration was measured in the unstretched (accommodated) and stretched (relaxed) states with a laser ray tracing system that delivered 51 equally spaced parallel rays along 1 meridian of the lens over the central 6-mm optical zone. A camera mounted below the lens was used to measure the ray height at multiple positions along the optical axis. For each entrance ray, the change in ray height with axial position was fitted with a third-order polynomial. The effective paraxial focal length and Zernike spherical aberration coefficients corresponding to a 6-mm pupil diameter were extracted from the fitted values. RESULTS: The unstretched lens power decreased with age from 59.3 ± 4.0 diopters (D) for young lenses to 45.7 ± 3.1 D for older lenses. The unstretched lens shifted toward less negative spherical aberration with age, from -6.3 ± 0.7 μm for young lenses to -5.0 ± 0.5 μm for older lenses. The power and spherical aberration of lenses in the stretched state were independent of age, with values of 33.5 ± 3.4 D and -2.6 ± 0.5 μm, respectively. CONCLUSIONS: Spherical aberration is negative in cynomolgus monkey lenses and becomes more negative with accommodation. These results are in good agreement with the predicted values using computational ray tracing in a lens model with a reconstructed gradient refractive index. The spherical aberration of the unstretched lens becomes less negative with age. Copyright 2015 The Association for Research in Vision and Ophthalmology, Inc.
PURPOSE: The purpose of this study was to quantify accommodation-induced changes in the spherical aberration of cynomolgus monkey lenses. METHODS: Twenty-four lenses from 20 cynomolgus monkeys (Macaca fascicularis; 4.4-16.0 years of age; postmortem time 13.5 ± 13.0 hours) were mounted in a lens stretcher. Lens spherical aberration was measured in the unstretched (accommodated) and stretched (relaxed) states with a laser ray tracing system that delivered 51 equally spaced parallel rays along 1 meridian of the lens over the central 6-mm optical zone. A camera mounted below the lens was used to measure the ray height at multiple positions along the optical axis. For each entrance ray, the change in ray height with axial position was fitted with a third-order polynomial. The effective paraxial focal length and Zernike spherical aberration coefficients corresponding to a 6-mm pupil diameter were extracted from the fitted values. RESULTS: The unstretched lens power decreased with age from 59.3 ± 4.0 diopters (D) for young lenses to 45.7 ± 3.1 D for older lenses. The unstretched lens shifted toward less negative spherical aberration with age, from -6.3 ± 0.7 μm for young lenses to -5.0 ± 0.5 μm for older lenses. The power and spherical aberration of lenses in the stretched state were independent of age, with values of 33.5 ± 3.4 D and -2.6 ± 0.5 μm, respectively. CONCLUSIONS: Spherical aberration is negative in cynomolgus monkey lenses and becomes more negative with accommodation. These results are in good agreement with the predicted values using computational ray tracing in a lens model with a reconstructed gradient refractive index. The spherical aberration of the unstretched lens becomes less negative with age. Copyright 2015 The Association for Research in Vision and Ophthalmology, Inc.
Entities:
Keywords:
crystalline lens; laser ray tracing; optics; spherical aberration
Authors: Bianca M Maceo; Fabrice Manns; David Borja; Derek Nankivil; Stephen Uhlhorn; Esdras Arrieta; Arthur Ho; Robert C Augusteyn; Jean-Marie Parel Journal: J Vis Date: 2011-11-30 Impact factor: 2.240
Authors: Bianca Maceo Heilman; Fabrice Manns; Marco Ruggeri; Arthur Ho; Alex Gonzalez; Cor Rowaan; Andres Bernal; Esdras Arrieta; Jean-Marie Parel Journal: Invest Ophthalmol Vis Sci Date: 2018-04-01 Impact factor: 4.799