Literature DB >> 25664880

Protein disulfide isomerase mediates dengue virus entry in association with lipid rafts.

Drishya Diwaker1, Kamla P Mishra, Lilly Ganju, Shashi B Singh.   

Abstract

Dengue virus (DENV) causes a febrile disease, infecting around 50-100 million people annually. The relationship between DENV proteins and host cellular responses during infection is unclear. This study investigated the interaction of host protein disulfide isomerase (PDI) with DENV proteins and role of lipid rafts in viral immunopathogenesis. Host viral protein interactions were studied by co-immunoprecipitation and co-localization. It was found that PDI interacts with DENV nonstructural protein 1 (NS1) intracellularly as well as on the surface in the lipid raft domain. Disruption of this key interaction between PDI and NS1 could be an important therapeutic strategy to block DENV infection.

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Year:  2015        PMID： 25664880     DOI： 10.1089/vim.2014.0095

Source DB:  PubMed          Journal:  Viral Immunol        ISSN： 0882-8245            Impact factor:   2.257


  16 in total

Review 1.  Stress proteins: the biological functions in virus infection, present and challenges for target-based antiviral drug development.

Authors:  Qianya Wan; Dan Song; Huangcan Li; Ming-Liang He
Journal:  Signal Transduct Target Ther       Date:  2020-07-13

2.  Crystal and solution structures of human protein-disulfide isomerase-like protein of the testis (PDILT) provide insight into its chaperone activity.

Authors:  Huanhuan Li; Kai Yang; Wenjia Wang; Yingbo Niu; Jun Li; Yuhui Dong; Yingfang Liu; Chih-Chen Wang; Lei Wang; Huanhuan Liang
Journal:  J Biol Chem       Date:  2017-12-04       Impact factor: 5.157

3.  ApoA1 Neutralizes Proinflammatory Effects of Dengue Virus NS1 Protein and Modulates Viral Immune Evasion.

Authors:  Diego R Coelho; Pedro H Carneiro; Lucas Mendes-Monteiro; Jonas N Conde; Iamara Andrade; Thu Cao; Diego Allonso; Michael White-Dibiasio; Richard J Kuhn; Ronaldo Mohana-Borges
Journal:  J Virol       Date:  2021-06-10       Impact factor: 5.103

4.  Protein Disulfide Isomerase Inhibitor Suppresses Viral Replication and Production during Antibody-Dependent Enhancement of Dengue Virus Infection in Human Monocytic Cells.

Authors:  Nantapon Rawarak; Aroonroong Suttitheptumrong; Onrapak Reamtong; Kobporn Boonnak; Sa-Nga Pattanakitsakul
Journal:  Viruses       Date:  2019-02-13       Impact factor: 5.048

Review 5.  Hijacking the Host Immune Cells by Dengue Virus: Molecular Interplay of Receptors and Dengue Virus Envelope.

Authors:  Feroza Begum; Sandeepan Das; Debica Mukherjee; Upasana Ray
Journal:  Microorganisms       Date:  2019-09-06

6.  A substrate-driven allosteric switch that enhances PDI catalytic activity.

Authors:  Roelof H Bekendam; Pavan K Bendapudi; Lin Lin; Partha P Nag; Jun Pu; Daniel R Kennedy; Alexandra Feldenzer; Joyce Chiu; Kristina M Cook; Bruce Furie; Mingdong Huang; Philip J Hogg; Robert Flaumenhaft
Journal:  Nat Commun       Date:  2016-08-30       Impact factor: 14.919

Review 7.  The Role of Host Cholesterol During Flavivirus Infection.

Authors:  Juan Fidel Osuna-Ramos; José Manuel Reyes-Ruiz; Rosa Maria Del Ángel
Journal:  Front Cell Infect Microbiol       Date:  2018-11-02       Impact factor: 5.293

8.  Male-Specific Protein Disulphide Isomerase Function is Essential for Plasmodium Transmission and a Vulnerable Target for Intervention.

Authors:  Fiona Angrisano; Katarzyna A Sala; Sofia Tapanelli; George K Christophides; Andrew M Blagborough
Journal:  Sci Rep       Date:  2019-12-04       Impact factor: 4.379

9.  Infectious bronchitis virus entry mainly depends on clathrin mediated endocytosis and requires classical endosomal/lysosomal system.

Authors:  Huan Wang; Xiao Yuan; Yingjie Sun; Xiang Mao; Chunchun Meng; Lei Tan; Cuiping Song; Xusheng Qiu; Chan Ding; Ying Liao
Journal:  Virology       Date:  2018-12-28       Impact factor: 3.616

Review 10.  Analogies Between Cancer-Derived Extracellular Vesicles and Enveloped Viruses with an Emphasis on Human Breast Cancer.

Authors:  Toni M Green; Mark F Santos; Sanford H Barsky; Germana Rappa; Aurelio Lorico
Journal:  Curr Pathobiol Rep       Date:  2016-08-27
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