Literature DB >> 25653942

Lead poisoning mimicking acute porphyria!

Akshatha L N1, Rukmini M S2, Mamatha T Shenoy1, Sadashiva Rao P3, Prashanth B4.   

Abstract

We are presenting a case of a 13-year-old autistic boy whose urine porphyrin test came positive on three separate occasions. The child was brought to emergency department of Kasturba Medical College Hospital, Attavar, Mangalore, India, with fever and acute abdominal pain, with no previous history of any serious illness. Investigations revealed thalassemia trait,microcytic hypochromic anaemia while the other biochemical and haematological parameters were normal. False positive urine porphyrin test may be seen in porphyria induced by liver cancer, hepatitis and heavy metal poisoning such as lead, arsenic and mercury. Blood lead (PbB) level was 59.5μg/dl. Further evaluation revealed a daily consumption of native medicine in the form of syrup.

Entities:  

Keywords:  Lead poisoning; Porphyria

Year:  2014        PMID: 25653942      PMCID: PMC4316248          DOI: 10.7860/JCDR/2014/10597.5315

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  7 in total

1.  Editorial role of a clinical biochemist in evaluating the impact of lead poisoning.

Authors:  Thuppil Venkatesh
Journal:  Indian J Clin Biochem       Date:  2013-01

2.  Drugs and false-positive screening tests for porphyria.

Authors:  J McEwen; C Paterson
Journal:  Br Med J       Date:  1972-02-12

3.  Clinical aspects of porphyrin measurement, other than lead poisoning.

Authors:  J M Lamon
Journal:  Clin Chem       Date:  1977-02       Impact factor: 8.327

Review 4.  Epigenetics of early-life lead exposure and effects on brain development.

Authors:  Marie-Claude Senut; Pablo Cingolani; Arko Sen; Adele Kruger; Asra Shaik; Helmut Hirsch; Steven T Suhr; Douglas Ruden
Journal:  Epigenomics       Date:  2012-12       Impact factor: 4.778

5.  Lead poisoning: clinical, biochemical, and haematological aspects of a recent outbreak.

Authors:  A Pagliuca; G J Mufti; D Baldwin; A N Lestas; R M Wallis; A J Bellingham
Journal:  J Clin Pathol       Date:  1990-04       Impact factor: 3.411

6.  Analysis of lead toxicity in human cells.

Authors:  Bruce S Gillis; Zarema Arbieva; Igor M Gavin
Journal:  BMC Genomics       Date:  2012-07-27       Impact factor: 3.969

7.  What caused hemolytic anemia and colicky abdominal pain? Lead!

Authors:  Se Heon Chang; Seon Bin Yoon; Jae Woong Lee; Duk Joo Lee
Journal:  Korean J Intern Med       Date:  2013-07-01       Impact factor: 2.884

  7 in total
  1 in total

1.  Occupational Lead Poisoning in a Patient with Acute Abdomen and Normocytic Anemia.

Authors:  Masahiko Kaneko; Takurou Kazatani; Hisaharu Shikata
Journal:  Intern Med       Date:  2020-06-15       Impact factor: 1.271

  1 in total

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