Takuji Matsumoto1, Muneharu Ando, Shunji Sasaki. 1. Department of Orthopedic Surgery, Nokami Kosei General Hospital, 198 Kobata, Kimino-Cho, Kaisou-Gun, Wakayama, 640-1141, Japan, matsumoto_t@nokami-hospital.jp.
Abstract
INTRODUCTION: We herein describe a case of delayed union of a lumbar spine fracture in a 70-year-old patient with diffuse idiopathic skeletal hyperostosis (DISH). CLINICAL COURSE AND RESULT: Because he decided not to undergo surgical treatment, we provided conservative treatment with teriparatide (TPTD). Union was obtained in 2 months, and no adverse events were observed during treatment. Six months after starting the TPTD, further bone formation was observed and the lumbar instability had resolved. CONCLUSION: This is the first report of successful use of TPTD to treat delayed union of a spine fracture in a patient with DISH without surgical intervention.
INTRODUCTION: We herein describe a case of delayed union of a lumbar spine fracture in a 70-year-old patient with diffuse idiopathic skeletal hyperostosis (DISH). CLINICAL COURSE AND RESULT: Because he decided not to undergo surgical treatment, we provided conservative treatment with teriparatide (TPTD). Union was obtained in 2 months, and no adverse events were observed during treatment. Six months after starting the TPTD, further bone formation was observed and the lumbar instability had resolved. CONCLUSION: This is the first report of successful use of TPTD to treat delayed union of a spine fracture in a patient with DISH without surgical intervention.
Authors: Robert Lindsay; Hua Zhou; Felicia Cosman; Jeri Nieves; David W Dempster; Anthony B Hodsman Journal: J Bone Miner Res Date: 2007-04 Impact factor: 6.741
Authors: Robert Lindsay; Wim H Scheele; Robert Neer; Gerhardt Pohl; Silvano Adami; Carlos Mautalen; Jean-Yves Reginster; Jan J Stepan; Stephen L Myers; Bruce H Mitlak Journal: Arch Intern Med Date: 2004-10-11