Jack V Tu1, Anna Chu2, Linda R Donovan2, Dennis T Ko2, Gillian L Booth2, Karen Tu2, Laura C Maclagan2, Helen Guo2, Peter C Austin2, William Hogg2, Moira K Kapral2, Harindra C Wijeysundera2, Clare L Atzema2, Andrea S Gershon2, David A Alter2, Douglas S Lee2, Cynthia A Jackevicius2, R Sacha Bhatia2, Jacob A Udell2, Mohammad R Rezai2, Thérèse A Stukel2. 1. From the Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada (J.V.T., A.C., L.R.D., D.T.K., G.L.B., K.T., L.C.M., H.G., P.C.A., W.H., M.K.K., H.C.W., C.L.A., A.S.G., D.A.A., D.S.L., C.A.J., R.S.B., J.A.U., M.R.R., T.A.S.); Division of Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada (J.V.T., D.T.K., H.C.W.); University of Toronto, Toronto, Ontario, Canada (J.V.T., A.C., D.T.K., G.L.B., K.T., P.C.A., M.K.K., H.C.W., C.L.A., A.S.G., D.A.A., D.S.L., C.A.J., R.S.B., J.A.U., T.A.S.); Division of Endocrinology, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada (G.L.B.); Toronto Western Hospital Family Health Team, University Health Network, Toronto, Ontario, Canada (K.T.); Ottawa Research Group for Primary Health Care, Ottawa, Ontario, Canada (W.H.); Department of Family Medicine, University of Ottawa, Ottawa, Ontario, Canada (W.H.); Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, Ontario, Canada (M.K.K.); Division of Emergency Medicine (C.L.A.) and Division of Respirology (A.S.G.), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Toronto Rehabilitation Institute, University Health Network, Toronto, Ontario, Canada (D.A.A.); Division of Cardiology, Peter Munk Cardiac Centre and Joint Department of Medical Imaging, University Health Network, Toronto, Ontario, Canada (D.S.L.); College of Pharmacy, Western University of Health Sciences, Pomona, CA (C.A.J.); Women's College Hospital Institute for Health Systems Solutions and Virtual Care, Toronto, Ontario, Canada (R.S.B.); Cardiovascular Division, Women's College Hospital, Toronto, Ontario, Canada (R.S.B., J.A.U.); and Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, NH (T.A.S.). tu@ices.on.ca. 2. From the Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada (J.V.T., A.C., L.R.D., D.T.K., G.L.B., K.T., L.C.M., H.G., P.C.A., W.H., M.K.K., H.C.W., C.L.A., A.S.G., D.A.A., D.S.L., C.A.J., R.S.B., J.A.U., M.R.R., T.A.S.); Division of Cardiology, Schulich Heart Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada (J.V.T., D.T.K., H.C.W.); University of Toronto, Toronto, Ontario, Canada (J.V.T., A.C., D.T.K., G.L.B., K.T., P.C.A., M.K.K., H.C.W., C.L.A., A.S.G., D.A.A., D.S.L., C.A.J., R.S.B., J.A.U., T.A.S.); Division of Endocrinology, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada (G.L.B.); Toronto Western Hospital Family Health Team, University Health Network, Toronto, Ontario, Canada (K.T.); Ottawa Research Group for Primary Health Care, Ottawa, Ontario, Canada (W.H.); Department of Family Medicine, University of Ottawa, Ottawa, Ontario, Canada (W.H.); Division of General Internal Medicine and Clinical Epidemiology, University Health Network, Toronto, Ontario, Canada (M.K.K.); Division of Emergency Medicine (C.L.A.) and Division of Respirology (A.S.G.), Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; Toronto Rehabilitation Institute, University Health Network, Toronto, Ontario, Canada (D.A.A.); Division of Cardiology, Peter Munk Cardiac Centre and Joint Department of Medical Imaging, University Health Network, Toronto, Ontario, Canada (D.S.L.); College of Pharmacy, Western University of Health Sciences, Pomona, CA (C.A.J.); Women's College Hospital Institute for Health Systems Solutions and Virtual Care, Toronto, Ontario, Canada (R.S.B.); Cardiovascular Division, Women's College Hospital, Toronto, Ontario, Canada (R.S.B., J.A.U.); and Dartmouth Institute for Health Policy and Clinical Practice, Lebanon, NH (T.A.S.).
Abstract
BACKGROUND: The CArdiovascular HEalth in Ambulatory care Research Team (CANHEART) is conducting a unique, population-based observational research initiative aimed at measuring and improving cardiovascular health and the quality of ambulatory cardiovascular care provided in Ontario, Canada. A particular focus will be on identifying opportunities to improve the primary and secondary prevention of cardiovascular events in Ontario's diverse multiethnic population. METHODS AND RESULTS: A population-based cohort comprising 9.8 million Ontario adults ≥20 years in 2008 was assembled by linking multiple electronic survey, health administrative, clinical, laboratory, drug, and electronic medical record databases using encoded personal identifiers. The cohort includes ≈9.4 million primary prevention patients and ≈400,000 secondary prevention patients. Follow-up on clinical events is achieved through record linkage to comprehensive hospitalization, emergency department, and vital statistics administrative databases. Profiles of cardiovascular health and preventive care will be developed at the health region level, and the cohort will be used to study the causes of regional variation in the incidence of major cardiovascular events and other important research questions. CONCLUSIONS: Linkage of multiple databases will enable the CANHEART study cohort to serve as a powerful big data resource for scientific research aimed at improving cardiovascular health and health services delivery. Study findings will be shared with clinicians, policy makers, and the public to facilitate population health interventions and quality improvement initiatives.
BACKGROUND: The CArdiovascular HEalth in Ambulatory care Research Team (CANHEART) is conducting a unique, population-based observational research initiative aimed at measuring and improving cardiovascular health and the quality of ambulatory cardiovascular care provided in Ontario, Canada. A particular focus will be on identifying opportunities to improve the primary and secondary prevention of cardiovascular events in Ontario's diverse multiethnic population. METHODS AND RESULTS: A population-based cohort comprising 9.8 million Ontario adults ≥20 years in 2008 was assembled by linking multiple electronic survey, health administrative, clinical, laboratory, drug, and electronic medical record databases using encoded personal identifiers. The cohort includes ≈9.4 million primary prevention patients and ≈400,000 secondary prevention patients. Follow-up on clinical events is achieved through record linkage to comprehensive hospitalization, emergency department, and vital statistics administrative databases. Profiles of cardiovascular health and preventive care will be developed at the health region level, and the cohort will be used to study the causes of regional variation in the incidence of major cardiovascular events and other important research questions. CONCLUSIONS: Linkage of multiple databases will enable the CANHEART study cohort to serve as a powerful big data resource for scientific research aimed at improving cardiovascular health and health services delivery. Study findings will be shared with clinicians, policy makers, and the public to facilitate population health interventions and quality improvement initiatives.
Authors: Jack V Tu; Laura C Maclagan; Dennis T Ko; Clare L Atzema; Gillian L Booth; Sharon Johnston; Karen Tu; Douglas S Lee; Arlene Bierman; Ruth Hall; R Sacha Bhatia; Andrea S Gershon; Sheldon W Tobe; Claudia Sanmartin; Peter Liu; Anna Chu Journal: CMAJ Open Date: 2017-04-25
Authors: Hong Chen; Jeffrey C Kwong; Ray Copes; Paul J Villeneuve; Mark S Goldberg; Sherry L Ally; Scott Weichenthal; Aaron van Donkelaar; Michael Jerrett; Randall V Martin; Jeffrey R Brook; Alexander Kopp; Richard T Burnett Journal: Int J Epidemiol Date: 2017-04-01 Impact factor: 7.196
Authors: Dennis T Ko; Atul Sivaswamy; Maneesh Sud; Gynter Kotrri; Paymon Azizi; Maria Koh; Peter C Austin; Douglas S Lee; Idan Roifman; George Thanassoulis; Karen Tu; Jacob A Udell; Harindra C Wijeysundera; Todd J Anderson Journal: CMAJ Date: 2020-04-27 Impact factor: 8.262
Authors: Jack V Tu; Anna Chu; Laura Maclagan; Peter C Austin; Sharon Johnston; Dennis T Ko; Ingrid Cheung; Clare L Atzema; Gillian L Booth; R Sacha Bhatia; Douglas S Lee; Cynthia A Jackevicius; Moira K Kapral; Karen Tu; Harindra C Wijeysundera; David A Alter; Jacob A Udell; Douglas G Manuel; Prosanta Mondal; William Hogg Journal: CMAJ Date: 2017-04-03 Impact factor: 8.262
Authors: Douglas G Manuel; Meltem Tuna; Carol Bennett; Deirdre Hennessy; Laura Rosella; Claudia Sanmartin; Jack V Tu; Richard Perez; Stacey Fisher; Monica Taljaard Journal: CMAJ Date: 2018-07-23 Impact factor: 8.262
Authors: Derrick Y Tam; Rodolfo V Rocha; Jiming Fang; Maral Ouzounian; Joanna Chikwe; Jennifer Lawton; Dennis T Ko; Peter C Austin; Mario Gaudino; Stephen E Fremes Journal: Heart Date: 2020-10-20 Impact factor: 5.994
Authors: Rajan Sacha Bhatia; Dennis T Ko; Cherry Chu; Ruth Croxford; Zachary Bouck; Tharmegan Tharmaratnam; Paul Dorian; Heather Ross; Peter C Austin; Kaveh Shojania; Shaun G Goodman Journal: CJC Open Date: 2021-02-09