| Literature DB >> 2564418 |
K Butterfield1, C G Fathman, R C Budd.
Abstract
The Pgp-1 glycoprotein (Ly-24 antigen) is acquired by mature murine T lymphocytes at the time of primary antigen stimulation Pgp-1 was previously shown to be a useful cell surface marker for distinguishing antigen-specific memory CD8+ T lymphocytes after immunization. Here we demonstrate that this observation extends to CD4+ T lymphocytes. Antigen-specific CD4+ T cells in mice immunized with sperm whale myoglobin or keyhole limpet hemocyanin were contained nearly exclusively in the minor Pgp-1+ subset.Entities:
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Year: 1989 PMID: 2564418 PMCID: PMC2189224 DOI: 10.1084/jem.169.4.1461
Source DB: PubMed Journal: J Exp Med ISSN: 0022-1007 Impact factor: 14.307