Literature DB >> 6265934

Human cell surface glycoprotein related to cell proliferation is the receptor for transferrin.

I S Trowbridge, M B Omary.   

Abstract

A cell surface glycoprotein antigen with an apparent molecular weight of about 100,000 that is selectively expressed on proliferating cells was purified from deoxycholate-solubilized membranes of a cultured human leukemic thymus-derived (T) cell line by affinity chromatography on a monoclonal antibody-Sepharose column. A conventional xenoantiserum prepared by immunization with the affinity-purified glycoprotein was found to contain antibodies against a serum component that bound tightly to cultured cells. This molecule was shown to be specifically associated with the cell surface glycoprotein purified by immunoprecipitation from lysates of cells. We have identified the serum component as transferrin and conclude that the membrane glycoprotein is the cell surface transferrin receptor.

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Year:  1981        PMID： 6265934      PMCID： PMC319495          DOI： 10.1073/pnas.78.5.3039

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  27 in total

1.  Identification of transferrin receptors on the surface of human cultured cells.

Authors:  T A Hamilton; H G Wada; H H Sussman
Journal:  Proc Natl Acad Sci U S A       Date:  1979-12       Impact factor: 11.205

2.  Modulation of cell surface iron transferrin receptors by cellular density and state of activation.

Authors:  J W Larrick; P Cresswell
Journal:  J Supramol Struct       Date:  1979

3.  Replacement of serum by insulin and transferrin supports growth and differentiation of the human promyelocytic cell line, HL-60.

Authors:  T R Breitman; S J Collins; B R Keene
Journal:  Exp Cell Res       Date:  1980-04       Impact factor: 3.905

Review 4.  Methods for growth of cultured cells in serum-free medium.

Authors:  D Barnes; G Sato
Journal:  Anal Biochem       Date:  1980-03-01       Impact factor: 3.365

5.  Disposition of T200 glycoprotein in the plasma membrane of a murine lymphoma cell line.

Authors:  M B Omary; I S Trowbridge
Journal:  J Biol Chem       Date:  1980-02-25       Impact factor: 5.157

6.  Transferrin receptor in human placental brush border membranes. Studies on the binding of transferrin to placental membrane vesicles and the identification of a placental brush border glycoprotein with high affinity for transferrin.

Authors:  H G Wada; P E Hass; H H Sussman
Journal:  J Biol Chem       Date:  1979-12-25       Impact factor: 5.157

7.  Discrete stages of human intrathymic differentiation: analysis of normal thymocytes and leukemic lymphoblasts of T-cell lineage.

Authors:  E L Reinherz; P C Kung; G Goldstein; R H Levey; S F Schlossman
Journal:  Proc Natl Acad Sci U S A       Date:  1980-03       Impact factor: 11.205

8.  Demonstration of transferrin receptors on human placental trophoblast.

Authors:  G M Galbraith; R M Galbraith; A Temple; W P Faulk
Journal:  Blood       Date:  1980-02       Impact factor: 22.113

9.  Human cell-surface glycoprotein with unusual properties.

Authors:  M B Omary; I S Trowbridge; J Minowada
Journal:  Nature       Date:  1980-08-28       Impact factor: 49.962

10.  Human homologue of murine T200 glycoprotein.

Authors:  M B Omary; I S Trowbridge; H A Battifora
Journal:  J Exp Med       Date:  1980-10-01       Impact factor: 14.307
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  156 in total

1.  Controlling tumor-derived and vascular endothelial cell growth: role of the 4Ff2 cell surface antigen.

Authors:  M Papetti; I M Herman
Journal:  Am J Pathol       Date:  2001-07       Impact factor: 4.307

2.  Burn injury dampens erythroid cell production through reprioritizing bone marrow hematopoietic response.

Authors:  Joseph A Posluszny; Kuzhali Muthumalaiappan; Ameet R Kini; Andrea Szilagyi; Li-Ke He; Yanxia Li; Richard L Gamelli; Ravi Shankar
Journal:  J Trauma       Date:  2011-11

3.  An anti-transferrin receptor-avidin fusion protein exhibits both strong proapoptotic activity and the ability to deliver various molecules into cancer cells.

Authors:  Patrick P Ng; Jay S Dela Cruz; David N Sorour; James M Stinebaugh; Seung-Uon Shin; Daniel S Shin; Sherie L Morrison; Manuel L Penichet
Journal:  Proc Natl Acad Sci U S A       Date:  2002-07-29       Impact factor: 11.205

Review 4.  Proliferation indices in malignant lymphomas.

Authors:  J Crocker
Journal:  Clin Exp Immunol       Date:  1989-09       Impact factor: 4.330

5.  Immunopathology of cutaneous T-cell lymphomas.

Authors:  K Nasu; J Said; E Vonderheid; J Olerud; D Sako; M Kadin
Journal:  Am J Pathol       Date:  1985-06       Impact factor: 4.307

6.  Antigenic stimulation regulates the level of expression of interleukin 2 receptor on human T cells.

Authors:  M E Hemler; M B Brenner; J M McLean; J L Strominger
Journal:  Proc Natl Acad Sci U S A       Date:  1984-04       Impact factor: 11.205

7.  Nuclear proteins TREF1 and TREF2 bind to the transcriptional control element of the transferrin receptor gene and appear to be associated as a heterodimer.

Authors:  M R Roberts; W K Miskimins; F H Ruddle
Journal:  Cell Regul       Date:  1989-11

Review 8.  A systems biology approach to iron metabolism.

Authors:  Julia Chifman; Reinhard Laubenbacher; Suzy V Torti
Journal:  Adv Exp Med Biol       Date:  2014       Impact factor: 2.622

9.  The effect of desferrioxamine on transferrin receptors, the cell cycle and growth rates of human leukaemic cells.

Authors:  A Bomford; J Isaac; S Roberts; A Edwards; S Young; R Williams
Journal:  Biochem J       Date:  1986-05-15       Impact factor: 3.857

10.  Identification of the parasite transferrin receptor of Plasmodium falciparum-infected erythrocytes and its acylation via 1,2-diacyl-sn-glycerol.

Authors:  K Haldar; C L Henderson; G A Cross
Journal:  Proc Natl Acad Sci U S A       Date:  1986-11       Impact factor: 11.205
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