Literature DB >> 25643657

The critical role of peptide chemistry in the life sciences.

Stephen B H Kent1.   

Abstract

Peptide chemistry plays a key role in the synthesis and study of protein molecules and their functions. Modern ligation methods enable the total synthesis of enzymes and the systematic dissection of the chemical basis of enzyme catalysis. Predicted developments in peptide science are described.
Copyright © 2015 European Peptide Society and John Wiley & Sons, Ltd.

Keywords:  Analytical characterization of synthetic peptides; Chemical protein synthesis; Enzymes; Novel protein covalent topologies; Post-translational modifications; Synthetic peptide vaccines

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Year:  2015        PMID: 25643657     DOI: 10.1002/psc.2754

Source DB:  PubMed          Journal:  J Pept Sci        ISSN: 1075-2617            Impact factor:   1.905


  6 in total

1.  Convenient synthesis of collagen-related tripeptides for segment condensation.

Authors:  Aubrey J Ellison; Brett VanVeller; Ronald T Raines
Journal:  Biopolymers       Date:  2015-11       Impact factor: 2.505

Review 2.  Novel protein science enabled by total chemical synthesis.

Authors:  Stephen B H Kent
Journal:  Protein Sci       Date:  2018-12-18       Impact factor: 6.725

3.  Sequence Diversification by Divergent C-Terminal Elongation of Peptides.

Authors:  Christine A Arbour; Ramona E Stamatin; Jennifer L Stockdill
Journal:  J Org Chem       Date:  2018-01-25       Impact factor: 4.354

4.  Design, synthesis and characterization of structurally dynamic cyclic N,S-acetals.

Authors:  Emily K Kirkeby; Andrew G Roberts
Journal:  Chem Commun (Camb)       Date:  2020-07-22       Impact factor: 6.222

5.  Extendable stapling of unprotected peptides by crosslinking two amines with o-phthalaldehyde.

Authors:  Bo Li; Lan Wang; Xiangxiang Chen; Xin Chu; Hong Tang; Jie Zhang; Gang He; Li Li; Gong Chen
Journal:  Nat Commun       Date:  2022-01-14       Impact factor: 14.919

6.  Characterization and Recombinant Expression of Terebrid Venom Peptide from Terebra guttata.

Authors:  John Moon; Juliette Gorson; Mary Elizabeth Wright; Laurel Yee; Samer Khawaja; Hye Young Shin; Yasmine Karma; Rajeeva Lochan Musunri; Michelle Yun; Mande Holford
Journal:  Toxins (Basel)       Date:  2016-03-03       Impact factor: 4.546

  6 in total

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