Literature DB >> 25641402

Influence of socioeconomic status on allograft and patient survival following kidney transplantation.

Frank L Ward1, Patrick O'Kelly, Fionnuala Donohue, Coilin ÓhAiseadha, Trutz Haase, Jonathan Pratschke, Declan G deFreitas, Howard Johnson, Peter J Conlon, Conall M O'Seaghdha.   

Abstract

AIM: Whether socioeconomic status confers worse outcomes after kidney transplantation is unknown. Its influence on allograft and patient survival following kidney transplantation in Ireland was examined.
METHODS: A retrospective, observational cohort study of adult deceased-donor first kidney transplant recipients from 1990 to 2009 was performed. Those with a valid Irish postal address were assigned a socioeconomic status score based on the Pobal Hasse-Pratschke deprivation index and compared in quartiles. Cox proportional hazards models and Kaplan-Meier survival analysis were used to investigate any significant association of socioeconomic status with patient and allograft outcomes.
RESULTS: A total of 1944 eligible kidney transplant recipients were identified. The median follow-up time was 8.2 years (interquartile range 4.4-13.3 years). Socioeconomic status was not associated with uncensored or death-censored allograft survival (hazard ratio (HR) 1.0, 95% confidence interval (CI) 0.99-1.00, P = 0.33 and HR 1.0, 95% CI 0.99-1.00, P = 0.37, respectively). Patient survival was not associated with socioeconomic status quartile (HR 1.0, 95% CI 0.93-1.08, P = 0.88). There was no significant difference among quartiles for uncensored or death-censored allograft survival at 5 and 10 years.
CONCLUSION: There was no socioeconomic disparity in allograft or patient outcomes following kidney transplantation, which may be partly attributable to the Irish healthcare model. This may give further impetus to calls in other jurisdictions for universal healthcare and medication coverage for kidney transplant recipients.
© 2015 Asian Pacific Society of Nephrology.

Entities:  

Keywords:  allograft survival; kidney transplantation; patient survival; socioeconomic status

Mesh:

Year:  2015        PMID: 25641402     DOI: 10.1111/nep.12410

Source DB:  PubMed          Journal:  Nephrology (Carlton)        ISSN: 1320-5358            Impact factor:   2.506


  2 in total

1.  County socioeconomic characteristics and pediatric renal transplantation outcomes.

Authors:  Rebecca Miller; Clifford Akateh; Noelle Thompson; Dmitry Tumin; Don Hayes; Sylvester M Black; Joseph D Tobias
Journal:  Pediatr Nephrol       Date:  2018-03-12       Impact factor: 3.714

2.  Association between social deprivation and incidence of first seizures and epilepsy: A prospective population-based cohort.

Authors:  Eimer M Maloney; Paul Corcoran; Daniel J Costello; Éilis J O'Reilly
Journal:  Epilepsia       Date:  2022-06-10       Impact factor: 6.740

  2 in total

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