Literature DB >> 25638306

Predictors of distress and poorer quality of life in High Grade Glioma patients.

Georgia K B Halkett1, Elizabeth A Lobb2, Michelle M Rogers3, Thérèse Shaw4, Anne P Long5, Helen R Wheeler6, Anna K Nowak7.   

Abstract

OBJECTIVE: To determine High Grade Glioma (HGG) patients' levels of distress and QOL during combined chemoradiotherapy, explore predictors of distress and QOL and prioritize patients' supportive care needs.
METHODS: Patients diagnosed with HGG who were referred for combined chemoradiotherapy were recruited. Participants completed demographics and questionnaires assessing distress, function, and supportive care needs. Descriptive statistics, correlation coefficients, t-tests and linear and logistic regression analyses were performed.
RESULTS: 116 participants completed the questionnaire. Participants scored lower for QOL in physical, functional and emotional domains than the general Australian population. Poor physical function, lower education levels, loss of employment and financial impact associated with diagnosis were consistently linked with multiple domains of distress, poor QOL and high unmet needs. Having a carer who was their partner predicted lower emotional well-being.
CONCLUSION: Patients with HGG experience a poor QOL, increased levels of distress and high unmet needs when commencing chemoradiotherapy. Patients who experience a financial impact and those with lower education levels may report higher levels of distress and increased unmet needs. PRACTICE IMPLICATIONS: Poor function, lower education and limited financial resources may help identify those who require additional screening and may benefit from additional information and psychological support at this time.
Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Distress; High Grade Glioma; Quality of life; Questionnaire; Supportive care needs

Mesh:

Year:  2015        PMID: 25638306     DOI: 10.1016/j.pec.2015.01.002

Source DB:  PubMed          Journal:  Patient Educ Couns        ISSN: 0738-3991


  27 in total

1.  Feasibility Testing and Refinement of a Supportive Educational Intervention for Carers of Patients with High-Grade Glioma - a Pilot Study.

Authors:  Georgia K B Halkett; Elizabeth A Lobb; Lisa Miller; Thérèse Shaw; Rachael Moorin; Anne Long; Anne King; Jenny Clarke; Stephanie Fewster; Anna K Nowak
Journal:  J Cancer Educ       Date:  2018-10       Impact factor: 2.037

2.  Do carer's levels of unmet needs change over time when caring for patients diagnosed with high-grade glioma and how are these needs correlated with distress?

Authors:  G K B Halkett; E A Lobb; T Shaw; M M Sinclair; L Miller; E Hovey; A K Nowak
Journal:  Support Care Cancer       Date:  2017-08-14       Impact factor: 3.603

3.  Distress and psychological morbidity do not reduce over time in carers of patients with high-grade glioma.

Authors:  Georgia K B Halkett; Elizabeth A Lobb; Thèrése Shaw; Michelle M Sinclair; Lisa Miller; Elizabeth Hovey; Anna K Nowak
Journal:  Support Care Cancer       Date:  2016-11-14       Impact factor: 3.603

Review 4.  Determining priority signs and symptoms for use as clinical outcomes assessments in trials including patients with malignant gliomas: Panel 1 Report.

Authors:  Terri S Armstrong; Allison M Bishof; Paul D Brown; Martin Klein; Martin J B Taphoorn; Christina Theodore-Oklota
Journal:  Neuro Oncol       Date:  2016-03       Impact factor: 12.300

5.  Factors associated with supportive care needs in glioma patients in the neuro-oncological outpatient setting.

Authors:  Mirjam Renovanz; Marlene Hechtner; Mareile Janko; Karoline Kohlmann; Jan Coburger; Minou Nadji-Ohl; Jochem König; Florian Ringel; Susanne Singer; Anne-Katrin Hickmann
Journal:  J Neurooncol       Date:  2017-05-19       Impact factor: 4.130

6.  Health-related quality of life in patients with high-grade gliomas: a quantitative longitudinal study.

Authors:  K Piil; J Jakobsen; K B Christensen; M Juhler; M Jarden
Journal:  J Neurooncol       Date:  2015-05-31       Impact factor: 4.130

7.  Evaluation of the psychological burden during the early disease trajectory in patients with intracranial tumors by the ultra-brief Patient Health Questionnaire for Depression and Anxiety (PHQ-4).

Authors:  Mirjam Renovanz; Sari Soebianto; Helena Tsakmaklis; Naureen Keric; Minou Nadji-Ohl; Manfred Beutel; Florian Ringel; Daniel Wollschläger; Anne-Katrin Hickmann
Journal:  Support Care Cancer       Date:  2019-03-23       Impact factor: 3.603

Review 8.  Health-related quality of life and psychological functioning in patients with primary malignant brain tumors: a systematic review of clinical, demographic and mental health factors.

Authors:  Paul D Baker; Jacki Bambrough; John R E Fox; Simon D Kyle
Journal:  Neurooncol Pract       Date:  2015-10-23

9.  Carers of patients with high-grade glioma report high levels of distress, unmet needs, and psychological morbidity during patient chemoradiotherapy.

Authors:  Anne Long; Georgia K B Halkett; Elizabeth A Lobb; Thérèse Shaw; Elizabeth Hovey; Anna K Nowak
Journal:  Neurooncol Pract       Date:  2015-10-15

10.  Compliance with patient-reported outcome assessment in glioma patients: predictors for drop out.

Authors:  Mirjam Renovanz; Marlene Hechtner; Karoline Kohlmann; Mareile Janko; Minou Nadji-Ohl; Susanne Singer; Florian Ringel; Jan Coburger; Anne-Katrin Hickmann
Journal:  Neurooncol Pract       Date:  2017-10-31
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