Paul D Baker1, Jacki Bambrough1, John R E Fox1, Simon D Kyle1. 1. Section for Clinical and Health Psychology, University of Manchester, Manchester, UK (P.D.B.); Department of Neuropsychology, Salford Royal NHS Foundation Trust, Salford, UK (J.B.); Department of Psychology, Royal Holloway, University of London, Surrey, UK (J.R.E.F.); Enfield Complex Care Team, Barnet, Enfield and Haringey Mental Health NHS Trust, London, UK (J.R.E.F.); Sleep and Circadian Neuroscience Institute, Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK (S.D.K.).
Abstract
BACKGROUND: The impact of primary malignant brain tumors on patient quality of life and psychological functioning is poorly understood, limiting the development of an evidence base for supportive interventions. We conducted a thorough systematic review and quality appraisal of the relevant literature to identify correlates of health-related quality of life (HRQoL) and psychological functioning (depression, anxiety and distress) in adults with primary malignant brain tumors. METHOD: Twenty-three articles met predefined inclusion criteria from a pool of peer-reviewed literature published between January 1984 and July 2015 (N = 2407). Methodological quality of included studies was assessed using an adapted version of the Newcastle-Ottawa Scale. RESULTS: The overall methodological quality of the literature was moderate. Factors relating consistently with HRQoL and/or psychological functioning were cognitive impairment, corticosteroid use, current or previous mental health difficulties, fatigue, functional impairment, performance status and motor impairment. CONCLUSIONS: Practitioners should remain alert to the presence of these factors as they may indicate patients at greater risk of poor HRQoL and psychological functioning. Attention should be directed towards improving patients' psychological functioning and maximizing functional independence to promote HRQoL. We outline several areas of future research with emphasis on improved methodological rigor.
BACKGROUND: The impact of primary malignant brain tumors on patient quality of life and psychological functioning is poorly understood, limiting the development of an evidence base for supportive interventions. We conducted a thorough systematic review and quality appraisal of the relevant literature to identify correlates of health-related quality of life (HRQoL) and psychological functioning (depression, anxiety and distress) in adults with primary malignant brain tumors. METHOD: Twenty-three articles met predefined inclusion criteria from a pool of peer-reviewed literature published between January 1984 and July 2015 (N = 2407). Methodological quality of included studies was assessed using an adapted version of the Newcastle-Ottawa Scale. RESULTS: The overall methodological quality of the literature was moderate. Factors relating consistently with HRQoL and/or psychological functioning were cognitive impairment, corticosteroid use, current or previous mental health difficulties, fatigue, functional impairment, performance status and motor impairment. CONCLUSIONS: Practitioners should remain alert to the presence of these factors as they may indicate patients at greater risk of poor HRQoL and psychological functioning. Attention should be directed towards improving patients' psychological functioning and maximizing functional independence to promote HRQoL. We outline several areas of future research with emphasis on improved methodological rigor.
Authors: C A Hahn; R H Dunn; P E Logue; J H King; C L Edwards; E C Halperin Journal: Int J Radiat Oncol Biol Phys Date: 2003-03-15 Impact factor: 7.038
Authors: M Klein; M J Taphoorn; J J Heimans; H M van der Ploeg; W P Vandertop; E F Smit; S Leenstra; C A Tulleken; W Boogerd; J S Belderbos; W Cleijne; N K Aaronson Journal: J Clin Oncol Date: 2001-10-15 Impact factor: 44.544
Authors: N Scott Litofsky; Elana Farace; Frederick Anderson; Christina A Meyers; Wei Huang; Edward R Laws Journal: Neurosurgery Date: 2004-02 Impact factor: 4.654
Authors: Thomas F Hack; J Dean Ruether; Marshall Pitz; Brian Thiessen; Lesley F Degner; Dan Chateau Journal: Support Care Cancer Date: 2021-02-17 Impact factor: 3.603
Authors: Julia T Daun; Lauren C Capozzi; Gloria Roldan Urgoiti; Meghan H McDonough; Jacob C Easaw; Margaret L McNeely; George J Francis; Tanya Williamson; Jessica Danyluk; Emma McLaughlin; Paula A Ospina; Marie de Guzman Wilding; Lori Radke; Amy Driga; Christine Lesiuk; S Nicole Culos-Reed Journal: Contemp Clin Trials Commun Date: 2022-05-25
Authors: Quirien Oort; Hanneke Zwinkels; Johan A F Koekkoek; Maaike J Vos; Jaap C Reijneveld; Martin J B Taphoorn; Linda Dirven Journal: Psychooncology Date: 2022-01-28 Impact factor: 3.955