Literature DB >> 25637559

NetExplore: a web server for modeling small network motifs.

Dmitri Papatsenko1, Ihor R Lemischka2.   

Abstract

MOTIVATION: Quantitative and qualitative assessment of biological data often produces small essential recurrent networks, containing 3-5 components called network motifs. In this context, model solutions for small network motifs represent very high interest.
RESULTS: Software package NetExplore has been created in order to generate, classify and analyze solutions for network motifs including up to six network components. NetExplore allows plotting and visualization of the solution's phase spaces and bifurcation diagrams.
AVAILABILITY AND IMPLEMENTATION: The current version of NetExplore has been implemented in Perl-CGI and is accessible at the following locations: http://line.bioinfolab.net/nex/NetExplore.htm and http://nex.autosome.ru/nex/NetExplore.htm.
© The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

Mesh:

Year:  2015        PMID: 25637559      PMCID: PMC4462664          DOI: 10.1093/bioinformatics/btv058

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  16 in total

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5.  A map of the cis-regulatory sequences in the mouse genome.

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Journal:  Nature       Date:  2012-08-02       Impact factor: 49.962

6.  The incoherent feedforward loop can provide fold-change detection in gene regulation.

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7.  Systems-level dynamic analyses of fate change in murine embryonic stem cells.

Authors:  Rong Lu; Florian Markowetz; Richard D Unwin; Jeffrey T Leek; Edoardo M Airoldi; Ben D MacArthur; Alexander Lachmann; Roye Rozov; Avi Ma'ayan; Laurie A Boyer; Olga G Troyanskaya; Anthony D Whetton; Ihor R Lemischka
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8.  The Drosophila gap gene network is composed of two parallel toggle switches.

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9.  Enhancer responses to similarly distributed antagonistic gradients in development.

Authors:  Robert P Zinzen; Dmitri Papatsenko
Journal:  PLoS Comput Biol       Date:  2007-03-29       Impact factor: 4.475

10.  A fast, robust and tunable synthetic gene oscillator.

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  2 in total

Review 1.  Systems Bioinformatics: increasing precision of computational diagnostics and therapeutics through network-based approaches.

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2.  Single-Cell Analyses of ESCs Reveal Alternative Pluripotent Cell States and Molecular Mechanisms that Control Self-Renewal.

Authors:  Dmitri Papatsenko; Henia Darr; Ivan V Kulakovskiy; Avinash Waghray; Vsevolod J Makeev; Ben D MacArthur; Ihor R Lemischka
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  2 in total

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