Literature DB >> 25631077

Modulation of flavivirus population diversity by RNA interference.

Doug E Brackney1, Erin E Schirtzinger2, Thomas D Harrison3, Gregory D Ebel3, Kathryn A Hanley2.   

Abstract

To test the hypothesis that RNA interference (RNAi) imposes diversifying selection on RNA virus genomes, we quantified West Nile virus (WNV) quasispecies diversity after passage in Drosophila cells in which RNAi was left intact, depleted, or stimulated against WNV. As predicted, WNV diversity was significantly lower in RNAi-depleted cells and significantly greater in RNAi-stimulated cells relative to that in controls. These findings reveal that an innate immune defense can shape viral population structure.
Copyright © 2015, American Society for Microbiology. All Rights Reserved.

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Year:  2015        PMID： 25631077      PMCID： PMC4403385          DOI： 10.1128/JVI.02612-14

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  36 in total

1.  Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity.

Authors:  Aimee L Jackson; Julja Burchard; Janell Schelter; B Nelson Chau; Michele Cleary; Lee Lim; Peter S Linsley
Journal:  RNA       Date:  2006-05-08       Impact factor: 4.942

2.  Essential function in vivo for Dicer-2 in host defense against RNA viruses in drosophila.

Authors:  Delphine Galiana-Arnoux; Catherine Dostert; Anette Schneemann; Jules A Hoffmann; Jean-Luc Imler
Journal:  Nat Immunol       Date:  2006-03-23       Impact factor: 25.606

3.  Acute emergence and reversion of influenza A virus quasispecies within CD8+ T cell antigenic peptides.

Authors:  Sophie A Valkenburg; Sergio Quiñones-Parra; Stephanie Gras; Naomi Komadina; Jodie McVernon; Zhongfang Wang; Hanim Halim; Pina Iannello; Catherine Cole; Karen Laurie; Anne Kelso; Jamie Rossjohn; Peter C Doherty; Stephen J Turner; Katherine Kedzierska
Journal:  Nat Commun       Date:  2013       Impact factor: 14.919

4.  Population variation of West Nile virus confers a host-specific fitness benefit in mosquitoes.

Authors:  Kelly A Fitzpatrick; Eleanor R Deardorff; Kendra Pesko; Doug E Brackney; Bo Zhang; Edward Bedrick; Pei-Yong Shi; Gregory D Ebel
Journal:  Virology       Date:  2010-08-15       Impact factor: 3.616

5.  Epitope-specific CD8+ T lymphocytes cross-recognize mutant simian immunodeficiency virus (SIV) sequences but fail to contain very early evolution and eventual fixation of epitope escape mutations during SIV infection.

Authors:  Evan M Cale; Peter Hraber; Elena E Giorgi; Will Fischer; Tanmoy Bhattacharya; Thomas Leitner; Wendy W Yeh; Cheryl Gleasner; Lance D Green; Cliff S Han; Bette Korber; Norman L Letvin
Journal:  J Virol       Date:  2011-02-09       Impact factor: 5.103

6.  Transport of dsRNA into cells by the transmembrane protein SID-1.

Authors:  Evan H Feinberg; Craig P Hunter
Journal:  Science       Date:  2003-09-12       Impact factor: 47.728

7.  RNA interference modulates replication of dengue virus in Drosophila melanogaster cells.

Authors:  Swati Mukherjee; Kathryn A Hanley
Journal:  BMC Microbiol       Date:  2010-04-27       Impact factor: 3.605

8.  Alphavirus-derived small RNAs modulate pathogenesis in disease vector mosquitoes.

Authors:  Kevin M Myles; Michael R Wiley; Elaine M Morazzani; Zach N Adelman
Journal:  Proc Natl Acad Sci U S A       Date:  2008-12-01       Impact factor: 11.205

9.  The outcome of hepatitis C virus infection is predicted by escape mutations in epitopes targeted by cytotoxic T lymphocytes.

Authors:  A L Erickson; Y Kimura; S Igarashi; J Eichelberger; M Houghton; J Sidney; D McKinney; A Sette; A L Hughes; C M Walker
Journal:  Immunity       Date:  2001-12       Impact factor: 31.745

Review 10.  The role of innate immunity in conditioning mosquito susceptibility to West Nile virus.

Authors:  Abhishek N Prasad; Doug E Brackney; Gregory D Ebel
Journal:  Viruses       Date:  2013-12-13       Impact factor: 5.048
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  25 in total

Review 1.  Arbovirus-mosquito interactions: RNAi pathway.

Authors:  Ken E Olson; Carol D Blair
Journal:  Curr Opin Virol       Date:  2015-12-06       Impact factor: 7.090

2.  Mosquitoes Transmit Unique West Nile Virus Populations during Each Feeding Episode.

Authors:  Nathan D Grubaugh; Joseph R Fauver; Claudia Rückert; James Weger-Lucarelli; Selene Garcia-Luna; Reyes A Murrieta; Alex Gendernalik; Darci R Smith; Doug E Brackney; Gregory D Ebel
Journal:  Cell Rep       Date:  2017-04-25       Impact factor: 9.423

Review 3.  Host-parasite co-evolution and its genomic signature.

Authors:  Dieter Ebert; Peter D Fields
Journal:  Nat Rev Genet       Date:  2020-08-28       Impact factor: 53.242

Review 4.  How Do Virus-Mosquito Interactions Lead to Viral Emergence?

Authors:  Claudia Rückert; Gregory D Ebel
Journal:  Trends Parasitol       Date:  2018-01-02

5.  Mutagen resistance and mutation restriction of St. Louis encephalitis virus.

Authors:  Sara B Griesemer; Laura D Kramer; Greta A Van Slyke; Janice D Pata; David W Gohara; Craig E Cameron; Alexander T Ciota
Journal:  J Gen Virol       Date:  2017-02       Impact factor: 3.891

Review 6.  Dynamics of West Nile virus evolution in mosquito vectors.

Authors:  Nathan D Grubaugh; Gregory D Ebel
Journal:  Curr Opin Virol       Date:  2016-10-24       Impact factor: 7.090

Review 7.  Promiscuous viruses-how do viruses survive multiple unrelated hosts?

Authors:  Gregory D Ebel
Journal:  Curr Opin Virol       Date:  2017-05-31       Impact factor: 7.090

8.  West Nile Virus fidelity modulates the capacity for host cycling and adaptation.

Authors:  Haley S Caldwell; Kiet Ngo; Janice D Pata; Laura D Kramer; Alexander T Ciota
Journal:  J Gen Virol       Date:  2020-02-18       Impact factor: 3.891

9.  Genetic Drift during Systemic Arbovirus Infection of Mosquito Vectors Leads to Decreased Relative Fitness during Host Switching.

Authors:  Nathan D Grubaugh; James Weger-Lucarelli; Reyes A Murrieta; Joseph R Fauver; Selene M Garcia-Luna; Abhishek N Prasad; William C Black; Gregory D Ebel
Journal:  Cell Host Microbe       Date:  2016-03-31       Impact factor: 21.023

10.  Breeding for Virus Resistance and Its Effects on Deformed Wing Virus Infection Patterns in Honey Bee Queens.

Authors:  David Claeys Bouuaert; Lina De Smet; Dirk C de Graaf
Journal:  Viruses       Date:  2021-06-04       Impact factor: 5.048
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