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Literature DB >> 25628394

Reply to "breakpoints and drug exposure are inevitably closely linked".

Tawanda Gumbo¹, Jotam G Pasipanodya¹, Peter Wash², André Burger², Helen McIlleron³.

Abstract

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Year: 2015 PMID： 25628394 PMCID： PMC4335911 DOI： 10.1128/AAC.04688-14

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

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10 in total

1. Breakpoints and drug exposure are inevitably closely linked.

Authors: J W C Alffenaar; O W Akkerman; M S Bolhuis; M J Boeree; W C M de Lange; T S van der Werf
Journal: Antimicrob Agents Chemother Date: 2015-02 Impact factor: 5.191

2. Redefining multidrug-resistant tuberculosis based on clinical response to combination therapy.

Authors: Tawanda Gumbo; Jotam G Pasipanodya; Peter Wash; André Burger; Helen McIlleron
Journal: Antimicrob Agents Chemother Date: 2014-08-04 Impact factor: 5.191

3. Impact of nonlinear interactions of pharmacokinetics and MICs on sputum bacillary kill rates as a marker of sterilizing effect in tuberculosis.

Authors: Emmanuel Chigutsa; Jotam G Pasipanodya; Marianne E Visser; Paul D van Helden; Peter J Smith; Frederick A Sirgel; Tawanda Gumbo; Helen McIlleron
Journal: Antimicrob Agents Chemother Date: 2014-10-13 Impact factor: 5.191

4. Serum drug concentrations predictive of pulmonary tuberculosis outcomes.

Authors: Jotam G Pasipanodya; Helen McIlleron; André Burger; Peter A Wash; Peter Smith; Tawanda Gumbo
Journal: J Infect Dis Date: 2013-07-29 Impact factor: 5.226

5. Isoniazid bactericidal activity and resistance emergence: integrating pharmacodynamics and pharmacogenomics to predict efficacy in different ethnic populations.

Authors: Tawanda Gumbo; Arnold Louie; Weiguo Liu; David Brown; Paul G Ambrose; Sujata M Bhavnani; George L Drusano
Journal: Antimicrob Agents Chemother Date: 2007-04-16 Impact factor: 5.191

6. New susceptibility breakpoints for first-line antituberculosis drugs based on antimicrobial pharmacokinetic/pharmacodynamic science and population pharmacokinetic variability.

Authors: Tawanda Gumbo
Journal: Antimicrob Agents Chemother Date: 2010-01-19 Impact factor: 5.191

Reply to "breakpoints and drug exposure are inevitably closely linked".

1. Breakpoints and drug exposure are inevitably closely linked.

2. Redefining multidrug-resistant tuberculosis based on clinical response to combination therapy.

3. Impact of nonlinear interactions of pharmacokinetics and MICs on sputum bacillary kill rates as a marker of sterilizing effect in tuberculosis.

4. Serum drug concentrations predictive of pulmonary tuberculosis outcomes.

5. Isoniazid bactericidal activity and resistance emergence: integrating pharmacodynamics and pharmacogenomics to predict efficacy in different ethnic populations.

6. New susceptibility breakpoints for first-line antituberculosis drugs based on antimicrobial pharmacokinetic/pharmacodynamic science and population pharmacokinetic variability.

7. Isoniazid pharmacokinetics-pharmacodynamics in an aerosol infection model of tuberculosis.

8. Concentration-dependent Mycobacterium tuberculosis killing and prevention of resistance by rifampin.

9. Pharmacokinetics-pharmacodynamics of rifampin in an aerosol infection model of tuberculosis.

10. The pyrazinamide susceptibility breakpoint above which combination therapy fails.