Literature DB >> 25624524

The Diamond Light Source and the challenges ahead for structural biology: some informal remarks.

V Ramakrishnan1.   

Abstract

The remarkable advances in structural biology in the past three decades have led to the determination of increasingly complex structures that lie at the heart of many important biological processes. Many of these advances have been made possible by the use of X-ray crystallography using synchrotron radiation. In this short article, some of the challenges and prospects that lie ahead will be summarized.
© 2015 The Author(s) Published by the Royal Society. All rights reserved.

Entities:  

Keywords:  macromolecular crystallography; structural biology; synchrotron radiation

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Substances:

Year:  2015        PMID: 25624524      PMCID: PMC4308983          DOI: 10.1098/rsta.2013.0156

Source DB:  PubMed          Journal:  Philos Trans A Math Phys Eng Sci        ISSN: 1364-503X            Impact factor:   4.226


  26 in total

1.  Diffraction cartography: applying microbeams to macromolecular crystallography sample evaluation and data collection.

Authors:  Matthew W Bowler; Matias Guijarro; Sebastien Petitdemange; Isabel Baker; Olof Svensson; Manfred Burghammer; Christoph Mueller-Dieckmann; Elspeth J Gordon; David Flot; Sean M McSweeney; Gordon A Leonard
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2010-07-09

2.  Structure of class B GPCR corticotropin-releasing factor receptor 1.

Authors:  Kaspar Hollenstein; James Kean; Andrea Bortolato; Robert K Y Cheng; Andrew S Doré; Ali Jazayeri; Robert M Cooke; Malcolm Weir; Fiona H Marshall
Journal:  Nature       Date:  2013-07-17       Impact factor: 49.962

3.  Automated data collection for macromolecular crystallography.

Authors:  Graeme Winter; Katherine E McAuley
Journal:  Methods       Date:  2011-07-07       Impact factor: 3.608

4.  Selenomethionyl proteins produced for analysis by multiwavelength anomalous diffraction (MAD): a vehicle for direct determination of three-dimensional structure.

Authors:  W A Hendrickson; J R Horton; D M LeMaster
Journal:  EMBO J       Date:  1990-05       Impact factor: 11.598

5.  Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation.

Authors:  Guillaume Lebon; Tony Warne; Patricia C Edwards; Kirstie Bennett; Christopher J Langmead; Andrew G W Leslie; Christopher G Tate
Journal:  Nature       Date:  2011-05-18       Impact factor: 49.962

6.  A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71.

Authors:  Xiangxi Wang; Wei Peng; Jingshan Ren; Zhongyu Hu; Jiwei Xu; Zhiyong Lou; Xumei Li; Weidong Yin; Xinliang Shen; Claudine Porta; Thomas S Walter; Gwyndaf Evans; Danny Axford; Robin Owen; David J Rowlands; Junzhi Wang; David I Stuart; Elizabeth E Fry; Zihe Rao
Journal:  Nat Struct Mol Biol       Date:  2012-03-04       Impact factor: 15.369

7.  In situ macromolecular crystallography using microbeams.

Authors:  Danny Axford; Robin L Owen; Jun Aishima; James Foadi; Ann W Morgan; James I Robinson; Joanne E Nettleship; Raymond J Owens; Isabel Moraes; Elizabeth E Fry; Jonathan M Grimes; Karl Harlos; Abhay Kotecha; Jingshan Ren; Geoff Sutton; Thomas S Walter; David I Stuart; Gwyndaf Evans
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2012-04-17

8.  Automated main-chain model building by template matching and iterative fragment extension.

Authors:  Thomas C Terwilliger
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2002-12-19

9.  Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM.

Authors:  Xueming Li; Paul Mooney; Shawn Zheng; Christopher R Booth; Michael B Braunfeld; Sander Gubbens; David A Agard; Yifan Cheng
Journal:  Nat Methods       Date:  2013-05-05       Impact factor: 28.547

10.  Unusual base pairing during the decoding of a stop codon by the ribosome.

Authors:  Israel S Fernández; Chyan Leong Ng; Ann C Kelley; Guowei Wu; Yi-Tao Yu; V Ramakrishnan
Journal:  Nature       Date:  2013-06-30       Impact factor: 49.962

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