Literature DB >> 25622699

The Hepatitis C treatment experience: Patients' perceptions of the facilitators of and barriers to uptake, adherence and completion.

Victoria A Sublette1, Sian K Smith, Jacob George, Kirsten McCaffery, Mark W Douglas.   

Abstract

OBJECTIVE: This study explores the perceptions of patients receiving treatment for Hepatitis C to determine what factors influence their decision to commence treatment, ability to maintain adherence and complete their treatment program.
DESIGN: Semi-structured interview techniques were used in a qualitative study of 20 patients undergoing treatment for Chronic Hepatitis C (CHC). MAIN OUTCOME MEASURES: To explore patients' perceived barriers and facilitators of Hepatitis C treatment adherence and completion.
RESULTS: Analysis of patient interviews identified four key themes: (1) motivations for commencing CHC treatment - fear of death and ridding themselves of stigma and shame; (2) the influential role of provider communication - patients reported that information and feedback that was personalised to their needs and lifestyles was the most effective for improving adherence to treatment; (3) facilitators of treatment adherence and completion - social, emotional and practical support improved adherence and completion, as did temporarily ceasing employment; (4) barriers to treatment adherence and completion - these included side effects, stigma, a complicated dosing schedule and limitations of the public healthcare system.
CONCLUSION: To increase treatment adherence and completion rates, a patient-centred approach is required that addresses patients' social, practical, and emotional support needs and adaptive coping strategies.

Entities:  

Keywords:  Hepatitis C treatment; Hepatitis C virus; coping strategies; qualitative research; treatment adherence

Mesh:

Substances:

Year:  2015        PMID: 25622699     DOI: 10.1080/08870446.2015.1012195

Source DB:  PubMed          Journal:  Psychol Health        ISSN: 0887-0446


  20 in total

1.  Value of Sustained Virologic Response in Patients with Hepatitis C as a Function of Time to Progression of End-Stage Liver Disease.

Authors:  Thomas Ward; Jason Gordon; Beverley Jones; Hayley Bennett; Samantha Webster; Anupama Kalsekar; Yong Yuan; Michael Brenner; Phil McEwan
Journal:  Clin Drug Investig       Date:  2017-01       Impact factor: 2.859

2.  HCV treatment barriers among HIV/HCV co-infected patients in the US: a qualitative study to understand low uptake among marginalized populations in the DAA era.

Authors:  Tessa M Nápoles; Abigail W Batchelder; Ada Lin; Lissa Moran; Mallory O Johnson; Martha Shumway; Anne F Luetkemeyer; Marion G Peters; Kellene V Eagen; Elise D Riley
Journal:  J Public Health (Oxf)       Date:  2019-12-20       Impact factor: 2.341

3.  Determinants of Hepatitis C Treatment Adherence and Treatment Completion Among Veterans in the Direct Acting Antiviral Era.

Authors:  Krupa Patel; Susan L Zickmund; Harleigh Jones; Andrea Reid; Linda Calgaro; Arielle Otero; Tami Coppler; Shari S Rogal
Journal:  Dig Dis Sci       Date:  2019-03-22       Impact factor: 3.199

Review 4.  Hepatitis C Virus Elimination in the Human Immunodeficiency Virus-Coinfected Population: Leveraging the Existing Human Immunodeficiency Virus Infrastructure.

Authors:  Meredith E Clement; Lauren F Collins; Julius M Wilder; Michael Mugavero; Taryn Barker; Susanna Naggie
Journal:  Infect Dis Clin North Am       Date:  2018-06       Impact factor: 5.982

5.  Determinants of stigma among patients with hepatitis C virus infection.

Authors:  M Elle Saine; Julia E Szymczak; Tyler M Moore; Laura P Bamford; Frances K Barg; Jason Schnittker; John H Holmes; Nandita Mitra; Vincent Lo Re
Journal:  J Viral Hepat       Date:  2020-06-23       Impact factor: 3.517

6.  Factors influencing treatment outcome in hepatitis C virus minority patients at an inner-city hospital: A STROBE-complaint article.

Authors:  Zaki A Sherif; Mehdi Nouraie; Rehana Begum; Ali Afsari; Babak Shokrani; Edward Lee; Adeyinka O Laiyemo; Hassan Brim; Hassan Ashktorab
Journal:  Medicine (Baltimore)       Date:  2020-04       Impact factor: 1.817

7.  The common sense model applied to hepatitis C: a qualitative analysis of the impact of disease comparison and witnessed death on hepatitis C illness perception.

Authors:  Stella A Safo; Abigail Batchelder; Deena Peyser; Alain H Litwin
Journal:  Harm Reduct J       Date:  2015-06-20

8.  Exploring Patient-Reported Costs Related to Hepatitis C on the Medical Crowdfunding Page GoFundMe®.

Authors:  T Joseph Mattingly; Karen Li; Arnold Ng; Tieu-Long Ton-Nu; Jennifer Owens
Journal:  Pharmacoecon Open       Date:  2020-09-30

9.  Perceived physical health outcomes of direct-acting antiviral treatment for hepatitis C: a qualitative study.

Authors:  Stelliana Goutzamanis; Danielle Horyniak; Joseph S Doyle; Margaret Hellard; Peter Higgs
Journal:  Harm Reduct J       Date:  2021-07-15

10.  A systematic review of community based hepatitis C treatment.

Authors:  Amanda J Wade; Vanessa Veronese; Margaret E Hellard; Joseph S Doyle
Journal:  BMC Infect Dis       Date:  2016-05-16       Impact factor: 3.090

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