Literature DB >> 25622093

Mohangamides A and B, new dilactone-tethered pseudo-dimeric peptides inhibiting Candida albicans isocitrate lyase.

Munhyung Bae1, Heegyu Kim, Kyuho Moon, Sang-Jip Nam, Jongheon Shin, Ki-Bong Oh, Dong-Chan Oh.   

Abstract

Mohangamides A and B (1-2) were discovered from a marine Streptomyces sp. collected in an intertidal mud flat. The structures of the compounds were elucidated as novel dilactone-tethered pseudodimeric peptides bearing two unusual acyl chains and 14 amino acid residues based on comprehensive spectroscopic analysis. The absolute configurations of the mohangamides were determined by chemical derivatizations, followed by chromatographic and spectroscopic analyses. Mohangamide A displayed strong inhibitory activity against Candida albicans isocitrate lyase.

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Year:  2015        PMID： 25622093     DOI： 10.1021/ol5037248

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  21 in total

1.  Application of 3D NMR for Structure Determination of Peptide Natural Products.

Authors:  Fan Zhang; Navid Adnani; Emmanuel Vazquez-Rivera; Doug R Braun; Marco Tonelli; David R Andes; Tim S Bugni
Journal:  J Org Chem       Date:  2015-08-21       Impact factor: 4.354

Review 2.  The Future of Antifungal Drug Therapy: Novel Compounds and Targets.

Authors:  Caroline Mota Fernandes; Deveney Dasilva; Krupanandan Haranahalli; J Brian McCarthy; John Mallamo; Iwao Ojima; Maurizio Del Poeta
Journal:  Antimicrob Agents Chemother       Date:  2021-01-20       Impact factor: 5.191

Review 3.  Potential Targets for Antifungal Drug Discovery Based on Growth and Virulence in Candida albicans.

Authors:  Xiuyun Li; Yinglong Hou; Longtao Yue; Shuyuan Liu; Juan Du; Shujuan Sun
Journal:  Antimicrob Agents Chemother       Date:  2015-07-20       Impact factor: 5.191

4.  Youssoufenes A2 and A3, Antibiotic Dimeric Cinnamoyl Lipids from the ΔdtlA Mutant of a Marine-Derived Streptomyces Strain.

Authors:  Jing Liu; Huayue Li; Zengzhi Liu; Tong Li; Fei Xiao; Wenli Li
Journal:  Mar Drugs       Date:  2022-06-15       Impact factor: 6.085

5.  Taeanamides A and B, Nonribosomal Lipo-Decapeptides Isolated from an Intertidal-Mudflat-Derived Streptomyces sp.

Authors:  Jinsheng Cui; Eunji Kim; Dong Hyun Moon; Tae Ho Kim; Ilnam Kang; Yeonjung Lim; Daniel Shin; Sunghoon Hwang; Young Eun Du; Myoung Chong Song; Munhyung Bae; Jang-Cheon Cho; Jichan Jang; Sang Kook Lee; Yeo Joon Yoon; Dong-Chan Oh
Journal:  Mar Drugs       Date:  2022-06-16       Impact factor: 6.085

Review 6.  Antimicrobial compounds from marine actinomycetes.

Authors:  Cong Wang; Yuanyu Lu; Shugeng Cao
Journal:  Arch Pharm Res       Date:  2020-07-20       Impact factor: 4.946

Review 7.  Marine Microbial-Derived Antibiotics and Biosurfactants as Potential New Agents against Catheter-Associated Urinary Tract Infections.

Authors:  Shuai Zhang; Xinjin Liang; Geoffrey Michael Gadd; Qi Zhao
Journal:  Mar Drugs       Date:  2021-04-29       Impact factor: 5.118

8.  QM-HiFSA-Aided Structure Determination of Succinilenes A-D, New Triene Polyols from a Marine-Derived Streptomyces sp.

Authors:  Munhyung Bae; So Hyun Park; Yun Kwon; Sang Kook Lee; Jongheon Shin; Joo-Won Nam; Dong-Chan Oh
Journal:  Mar Drugs       Date:  2017-02-14       Impact factor: 5.118

9.  Hormaomycins B and C: New Antibiotic Cyclic Depsipeptides from a Marine Mudflat-Derived Streptomyces sp.

Authors:  Munhyung Bae; Beomkoo Chung; Ki-Bong Oh; Jongheon Shin; Dong-Chan Oh
Journal:  Mar Drugs       Date:  2015-08-14       Impact factor: 5.118

Review 10.  Recent updates of marine antimicrobial peptides.

Authors:  Mohammad H Semreen; Mohammed I El-Gamal; Shifaa Abdin; Hajar Alkhazraji; Leena Kamal; Saba Hammad; Faten El-Awady; Dima Waleed; Layal Kourbaj
Journal:  Saudi Pharm J       Date:  2018-01-04       Impact factor: 4.330
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