Literature DB >> 25620854

Heme oxygenase-1-mediated host cell response inhibits the susceptibility of prostate cancer cells to retroviral infection and retards their proliferation.

Zhao-Hua Zhou1, Namita Kumari2, Jennifer Catalano3, Sergei Nekhai2, Jasen Wise4, Kenneth M Yamada5, Subhash Dhawan6.   

Abstract

Xenotropic murine leukemia virus-related virus (XMRV) resembles endogenous murine leukemia virus and was used in this study as a model for a new retrovirus infecting human cells. We demonstrate that induction of an HO-1-mediated host cell response inhibited the susceptibility of LNCaP prostate cancer cells to XMRV infection and efficiently retarded the growth of these prostate cancer cells. Our studies delineate a role of HO-1 in the host defense against retroviral infections and may provide novel therapeutic strategies for the treatment of HO-1-sensitive prostate cancer.

Entities:  

Keywords:  XMRV infection; gene expression; heme oxygenase-1; host factors

Year:  2013        PMID： 25620854      PMCID： PMC4302767     

Source DB:  PubMed          Journal:  Curr Trends Immunol        ISSN： 0972-4567


  11 in total

1.  Treatment of recurrent allograft dysfunction with intravenous hematin after liver transplantation for erythropoietic protoporphyria.

Authors:  Evan S Dellon; Zbigniew M Szczepiorkowski; Walter H Dzik; Fiona Graeme-Cook; Alain Ades; Joseph R Bloomer; A Benedict Cosimi; Raymond T Chung
Journal:  Transplantation       Date:  2002-03-27       Impact factor: 4.939

2.  Acute porphyria: treatment with heme.

Authors:  R Tenhunen; P Mustajoki
Journal:  Semin Liver Dis       Date:  1998       Impact factor: 6.115

3.  Failure to confirm XMRV/MLVs in the blood of patients with chronic fatigue syndrome: a multi-laboratory study.

Authors:  Graham Simmons; Simone A Glynn; Anthony L Komaroff; Judy A Mikovits; Leslie H Tobler; John Hackett; Ning Tang; William M Switzer; Walid Heneine; Indira K Hewlett; Jiangqin Zhao; Shyh-Ching Lo; Harvey J Alter; Jeffrey M Linnen; Kui Gao; John M Coffin; Mary F Kearney; Francis W Ruscetti; Max A Pfost; James Bethel; Steven Kleinman; Jerry A Holmberg; Michael P Busch
Journal:  Science       Date:  2011-09-22       Impact factor: 47.728

4.  Calcitonin increases tumorigenicity of prostate cancer cells: evidence for the role of protein kinase A and urokinase-type plasminogen receptor.

Authors:  Shibu Thomas; Srinivasulu Chigurupati; Muralidharan Anbalagan; Girish Shah
Journal:  Mol Endocrinol       Date:  2006-03-30

Review 5.  Evidence and controversies on the role of XMRV in prostate cancer and chronic fatigue syndrome.

Authors:  Luis Menéndez-Arias
Journal:  Rev Med Virol       Date:  2010-11-26       Impact factor: 6.989

6.  XMRV: usage of receptors and potential co-receptors.

Authors:  Mohan Kumar Haleyur Giri Setty; Krishnakumar Devadas; Viswanath Ragupathy; Veerasamy Ravichandran; Shixing Tang; Owen Wood; Durga Sivacharan Gaddam; Sherwin Lee; Indira K Hewlett
Journal:  Virol J       Date:  2011-09-06       Impact factor: 4.099

7.  Hemin activation ameliorates HIV-1 infection via heme oxygenase-1 induction.

Authors:  Krishnakumar Devadas; Subhash Dhawan
Journal:  J Immunol       Date:  2006-04-01       Impact factor: 5.422

8.  Detection of an infectious retrovirus, XMRV, in blood cells of patients with chronic fatigue syndrome.

Authors:  Vincent C Lombardi; Francis W Ruscetti; Jaydip Das Gupta; Max A Pfost; Kathryn S Hagen; Daniel L Peterson; Sandra K Ruscetti; Rachel K Bagni; Cari Petrow-Sadowski; Bert Gold; Michael Dean; Robert H Silverman; Judy A Mikovits
Journal:  Science       Date:  2009-10-08       Impact factor: 47.728

9.  Identification of XMRV infection-associated microRNAs in four cell types in culture.

Authors:  Ketha V K Mohan; Krishnakumar Devadas; Shilpakala Sainath Rao; Indira Hewlett; Chintamani Atreya
Journal:  PLoS One       Date:  2012-03-16       Impact factor: 3.240

10.  Susceptibility of human primary neuronal cells to xenotropic murine leukemia virus-related (XMRV) virus infection.

Authors:  Veerasamy Ravichandran; Eugen O Major; Carol Ibe; Maria Chiara Monaco; Mohan Kumar Haleyur Girisetty; Indira K Hewlett
Journal:  Virol J       Date:  2011-09-20       Impact factor: 4.099
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  6 in total

1.  Hemin activation of innate cellular response blocks human immunodeficiency virus type-1-induced osteoclastogenesis.

Authors:  Kazuyo Takeda; Rewati Adhikari; Kenneth M Yamada; Subhash Dhawan
Journal:  Biochem Biophys Res Commun       Date:  2015-05-19       Impact factor: 3.575

2.  Nrf2-dependent induction of innate host defense via heme oxygenase-1 inhibits Zika virus replication.

Authors:  Hanxia Huang; Barry Falgout; Kazuyo Takeda; Kenneth M Yamada; Subhash Dhawan
Journal:  Virology       Date:  2017-01-06       Impact factor: 3.616

3.  Defective iron homeostasis in human immunodeficiency virus type-1 latency.

Authors:  Hanxia Huang; Zhao-Hua Zhou; Rewati Adhikari; Kenneth M Yamada; Subhash Dhawan
Journal:  Curr Trends Immunol       Date:  2016

4.  Non-coding RNAs and heme oxygenase-1 in vaccinia virus infection.

Authors:  Clement A Meseda; Kumar Srinivasan; Jasen Wise; Jennifer Catalano; Kenneth M Yamada; Subhash Dhawan
Journal:  Biochem Biophys Res Commun       Date:  2014-10-18       Impact factor: 3.575

5.  Therapeutic potential of the heme oxygenase-1 inducer hemin against Ebola virus infection.

Authors:  Hanxia Huang; Krishnamurthy Konduru; Veronica Solovena; Zhao-Hua Zhou; Namita Kumari; Kazuyo Takeda; Sergei Nekhai; Sina Bavari; Gerardo G Kaplan; Kenneth M Yamada; Subhash Dhawan
Journal:  Curr Trends Immunol       Date:  2016

6.  Hemin activation abrogates Mycoplasma hyorhinis replication in chronically infected prostate cancer cells via heme oxygenase-1 induction.

Authors:  Hanxia Huang; Alena Dabrazhynetskaya; Jacob Pluznik; Jiwen Zheng; Yong Wu; Vladimir Chizhikov; Paul W Buehler; Kenneth M Yamada; Subhash Dhawan
Journal:  FEBS Open Bio       Date:  2021-09-09       Impact factor: 2.693
  6 in total

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