Literature DB >> 25620530

Adherence to HIV care after pregnancy among women in sub-Saharan Africa: falling off the cliff of the treatment cascade.

Christina Psaros1, Jocelyn E Remmert, David R Bangsberg, Steven A Safren, Jennifer A Smit.   

Abstract

Increased access to testing and treatment means HIV can be managed as a chronic illness, though successful management requires continued engagement with the health care system. Most of the global HIV burden is in sub-Saharan Africa where rates of new infections are consistently higher in women versus men. Pregnancy is often the point at which an HIV diagnosis is made. While preventing mother to child transmission (PMTCT) interventions significantly reduce the rate of vertical transmission of HIV, women must administer ARVs to their infants, adhere to breastfeeding recommendations, and test their infants for HIV after childbirth. Some women will be expected to remain on the ARVs initiated during pregnancy, while others are expected to engage in routine testing so treatment can be reinitiated when appropriate. The postpartum period presents many barriers to sustained treatment adherence and engagement in care. While some studies have examined adherence to postpartum PMTCT guidelines, few have focused on continued engagement in care by the mother, and very few examine adherence beyond the 6-week postpartum visit. Here, we attempt to identify gaps in the research literature and make recommendations on how to address barriers to ongoing postpartum HIV care.

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Year:  2015        PMID: 25620530      PMCID: PMC4370783          DOI: 10.1007/s11904-014-0252-6

Source DB:  PubMed          Journal:  Curr HIV/AIDS Rep        ISSN: 1548-3568            Impact factor:   5.071


  34 in total

1.  Reasons for loss to follow-up among mothers registered in a prevention-of-mother-to-child transmission program in rural Malawi.

Authors:  L D Bwirire; M Fitzgerald; R Zachariah; V Chikafa; M Massaquoi; M Moens; K Kamoto; E J Schouten
Journal:  Trans R Soc Trop Med Hyg       Date:  2008-05-16       Impact factor: 2.184

2.  Looking to the future: South African men and women negotiating HIV risk and relationship intimacy.

Authors:  Deborah Mindry; Suzanne Maman; Admire Chirowodza; Tshifhiwa Muravha; Heidi van Rooyen; Thomas Coates
Journal:  Cult Health Sex       Date:  2011-05

3.  Exploring socio-economic conditions and poor follow-up rates of HIV-exposed infants in Johannesburg, South Africa.

Authors:  S A Jones; G G Sherman; C A Varga
Journal:  AIDS Care       Date:  2005-05

4.  PMTCT from research to reality--results from a routine service.

Authors:  G G Sherman; S A Jones; A H Coovadia; M F Urban; K D Bolton
Journal:  S Afr Med J       Date:  2004-04

Review 5.  Adherence to antiretroviral therapy during and after pregnancy in low-income, middle-income, and high-income countries: a systematic review and meta-analysis.

Authors:  Jean B Nachega; Olalekan A Uthman; Jean Anderson; Karl Peltzer; Sarah Wampold; Mark F Cotton; Edward J Mills; Yuh-Shan Ho; Jeffrey S A Stringer; James A McIntyre; Lynne M Mofenson
Journal:  AIDS       Date:  2012-10-23       Impact factor: 4.177

6.  Women's expectations of treatment and care after an antenatal HIV diagnosis in Lilongwe, Malawi.

Authors:  Jennifer M Levy
Journal:  Reprod Health Matters       Date:  2009-05

Review 7.  Community strategies that improve care and retention along the prevention of mother-to-child transmission of HIV cascade: a review.

Authors:  Yabsera Marcos; Benjamin Ryan Phelps; Gretchen Bachman
Journal:  J Int AIDS Soc       Date:  2012-07-11       Impact factor: 5.396

8.  Prevention of mother-to-child transmission of HIV infection: views and perceptions about swallowing nevirapine in rural Lilongwe, Malawi.

Authors:  Deirdre A O'Gorman; Lot J Nyirenda; Sally J Theobald
Journal:  BMC Public Health       Date:  2010-06-21       Impact factor: 3.295

9.  Realities and Challenges of a Five Year Follow Up of Mother and Child Pairs on a PMTCT Program in Zimbabwe.

Authors:  E N Kurewa; G Q Kandawasvika; F Mhlanga; M Munjoma; M P Mapingure; P Chandiwana; M Z Chirenje; S Rusakaniko; B Stray-Pedersen
Journal:  Open AIDS J       Date:  2011-06-14

Review 10.  A systematic review of health system barriers and enablers for antiretroviral therapy (ART) for HIV-infected pregnant and postpartum women.

Authors:  Christopher J Colvin; Sarah Konopka; John C Chalker; Edna Jonas; Jennifer Albertini; Anouk Amzel; Karen Fogg
Journal:  PLoS One       Date:  2014-10-10       Impact factor: 3.240

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  44 in total

1.  A Self-Reported Adherence Measure to Screen for Elevated HIV Viral Load in Pregnant and Postpartum Women on Antiretroviral Therapy.

Authors:  Tamsin Phillips; Kirsty Brittain; Claude A Mellins; Allison Zerbe; Robert H Remien; Elaine J Abrams; Landon Myer; Ira B Wilson
Journal:  AIDS Behav       Date:  2017-02

2.  Decreases in Self-Reported ART Adherence Predict HIV Viremia Among Pregnant and Postpartum South African Women.

Authors:  Tamsin K Phillips; Ira B Wilson; Kirsty Brittain; Allison Zerbe; Claude A Mellins; Robert H Remien; Catherine Orrell; Elaine J Abrams; Landon Myer
Journal:  J Acquir Immune Defic Syndr       Date:  2019-03-01       Impact factor: 3.731

3.  A Systematic Review and Meta-analysis of Antiretroviral Therapy (ART) Adherence Interventions for Women Living with HIV.

Authors:  Jennifer A Pellowski; Devon M Price; Abigail D Harrison; Emily L Tuthill; Landon Myer; Don Operario; Mark N Lurie
Journal:  AIDS Behav       Date:  2019-08

4.  Retention in HIV Care During Pregnancy and the Postpartum Period in the Option B+ Era: Systematic Review and Meta-Analysis of Studies in Africa.

Authors:  Brandon A Knettel; Cody Cichowitz; James Samwel Ngocho; Elizabeth T Knippler; Lilian N Chumba; Blandina T Mmbaga; Melissa H Watt
Journal:  J Acquir Immune Defic Syndr       Date:  2018-04-15       Impact factor: 3.731

Review 5.  Mother and child both matter: reconceptualizing the prevention of mother-to-child transmission care continuum.

Authors:  Margaret L McNairy; Chloe A Teasdale; Wafaa M El-Sadr; Vidya Mave; Elaine J Abrams
Journal:  Curr Opin HIV AIDS       Date:  2015-11       Impact factor: 4.283

6.  Retention in HIV Care Among HIV-Seropositive Pregnant and Postpartum Women in Uganda: Results of a Randomized Controlled Trial.

Authors:  Lora L Sabin; Nafisa Halim; Davidson H Hamer; Elizabeth M Simmons; Sivani Jonnalagadda; Anna Larson Williams; Harriet Chemusto; Allen L Gifford; Rachael Bonawitz; Philip Aroda; Mary DeSilva; Julia Gasuza; Barbara Mukasa; Lisa J Messersmith
Journal:  AIDS Behav       Date:  2020-11

7.  "You must leave but I didn't want to leave": qualitative evaluation of the integration of ART into postnatal maternal and child health services in Cape Town, South Africa.

Authors:  Jennifer A Pellowski; Alison Z Weber; Tamsin K Phillips; Kirsty Brittain; Allison Zerbe; Elaine J Abrams; Landon Myer
Journal:  AIDS Care       Date:  2019-08-27

8.  Cryptococcosis in pregnancy and the postpartum period: Case series and systematic review with recommendations for management.

Authors:  Katelyn A Pastick; Elizabeth Nalintya; Lillian Tugume; Kenneth Ssebambulidde; Nicole Stephens; Emily E Evans; Jane Frances Ndyetukira; Edwin Nuwagira; Caleb Skipper; Conrad Muzoora; David B Meya; Joshua Rhein; David R Boulware; Radha Rajasingham
Journal:  Med Mycol       Date:  2020-04-01       Impact factor: 4.076

9.  Vulnerable at Each Step in the PMTCT Care Cascade: High Loss to Follow Up During Pregnancy and the Postpartum Period in Tanzania.

Authors:  Cody Cichowitz; Festo Mazuguni; Linda Minja; Prosper Njau; Gretchen Antelman; James Ngocho; Brandon A Knettel; Melissa H Watt; Blandina T Mmbaga
Journal:  AIDS Behav       Date:  2019-07

10.  Childbirth experiences of women living with HIV: a neglected event in the prevention of mother-to-child transmission care continuum.

Authors:  Cody Cichowitz; Melissa H Watt; Blandina T Mmbaga
Journal:  AIDS       Date:  2018-07-17       Impact factor: 4.177

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